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Images are at the heart of our science, and we have selected some of our favorite images to share with you.  If you would like a high-resolution version or would like to discuss permission to reproduce, please contact the AOIP via email.

Keyword

Condition

Imaging Modality

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OCT image from a subject with Achromatopsia

ACHM_OCT.jpg

This is an OCT image from a subject with Achromatopsia. Some photoreceptor disruption at the fovea is seen in this image.

Condition
  • Achromatopsia
Imaging Modality
  • OCT-Bioptigen
Confocal, split-detector and color merged photoreceptor image

Achromat-25-um-scalebar.jpg

Adaptive optics confocal image (left), split-detector image (middle) and color merged image (right - confocal is displayed in orange, split-detector is shown in blue) of the photoreceptor mosaic in a patient with achromatopsia at 2° from fixation. Scale bar 25µm

Condition
  • Achromatopsia
Imaging Modality
  • Adaptive Optics
Albinism hypoplasia OCT

Albinism hypoplasia OCT

OCT image through the central retina of a patient with X-linked ocular albinism, illustrating the absence of a foveal pit (foveal hypoplasia)

Condition
  • Albinism
Imaging Modality
  • OCT-Bioptigen
AO flood voronoi

AO flood voronoi

Image of the human cone mosaic, with the Voronoi domain of each cone superimposed. Voronoi analyses are used to characterize the packing geometry of the cone mosaic.

Condition
  • Normal
Imaging Modality
  • Adaptive Optics
AOSLO fovea periphery

AOSLO fovea periphery

The top images are of the cones at the center of the fovea, while the bottom images are of the peripheral retina (small cells are rods, larger cells are cones).

Condition
  • Normal
Imaging Modality
  • Adaptive Optics
AOSLO peripheral mosaic

AOSLO peripheral mosaic

Peripheral photoreceptor mosaic image generated by registering and averaging images taken over a span of 2 hours.

Condition
  • Normal
Imaging Modality
  • Adaptive Optics
AOSLO Retinitis Pigmentosa foveal cone magnified

AOSLO Retinitis Pigmentosa foveal cone magnified

Magnified image of the normal appearance of the central foveal cone mosaic in a patient with retinitis pigmentosa (RP).

Condition
  • Retinitis Pigmentosa
Imaging Modality
  • Adaptive Optics
Apodized rods and cones

Apodized Rods and Cones

Image of cone and rod photoreceptors taken with and without (pupil apodization) a technique demonstrated by Yusufu Sulai and Alfredo Dubra to enhance the contrast of rod photoreceptors. [PDF]

Condition
  • Normal
Imaging Modality
  • Adaptive Optics
Basal Laminar Drusen fluorescein angiography

Basal Laminar Drusen fluorescein angiography

Fluorescein angiography image of a patient with basal laminar drusen.

Condition
  • Basal Laminar Drusen
Imaging Modality
  • Fluorescein Angiography
Best Disease AOSLO image with lesion

Best Disease AOSLO image with lesion

Montage of the photoreceptor mosaic in a patient with Best disease, obtained with an adaptive optics scanning light ophthalmoscope.

Condition
  • Best Disease
Imaging Modality
  • Adaptive Optics
Best Disease Color Fundus

Best Disease Color Fundus

Color fundus image from a patient with Best disease, showing the classic "egg-yolk" lesion.

Condition
  • Best Disease
Imaging Modality
  • Color Fundus - Visucam
Best Disease OCT fovea

Best Disease OCT fovea

OCT image through the fovea in a patient with Best disease, allowing visualization of the extent of the elevated lesion.

Condition
  • Best Disease
Imaging Modality
  • OCT-Bioptigen
Choroideremia carrier FAF Optos

Choroideremia carrier FAF Optos

Wide-field autofluorescence image from a female carrier of choroideremia obtained using the Optos imaging system.

Condition
  • Choroideremia
Imaging Modality
  • Autofluorescence - Optos
Choroideremia carrier FAF Spectralis

Choroideremia carrier FAF Spectralis

Fundus autofluorescence image from a female carrier of choroideremia obtained using the Spectralis imaging system.

Condition
  • Choroideremia
Imaging Modality
  • Autofluorescence - Spectralis
Choroideremia FAF

Choroideremia FAF

Fundus autofluorescence image from a patient with choroideremia obtained using the Spectralis imaging system.

Condition
  • Choroideremia
Imaging Modality
  • Autofluorescence - Spectralis
Choroideremia OCT ORT

Choroideremia OCT ORT

Volume intensity projection (VIP) image from a patient with advanced choroideremia, with corresponding horizontal and vertical OCT B-scans.

Condition
  • Choroideremia
Imaging Modality
  • OCT-Bioptigen
CHD color fundus - visucam

choroideremiafundus1.jpg

Color fundus - Visucam image from a patient with choroideremia.

Condition
  • Choroideremia
Imaging Modality
  • Color Fundus - Visucam
Dark-field Image of RPE Cell Mosaic

Dark-field Image of RPE Cell Mosaic

The dark-field RPE imaging technique is able to resolve nearly all cells in the fovea in some volunteers using near-infrared light.

Condition
  • Normal
Imaging Modality
  • Adaptive Optics
Drusen Multimodal Imaging

Drusen Multimodal Imaging

Multimodal imaging - top left is a magnified fundus autofluorescence, top right is the corresponding photoreceptor mosaic, bottom is an OCT B-scan of the same druse.

Condition
  • Drusen
Imaging Modality
  • Multimodal
Drusen OCT

Drusen OCT

High-resolution Bioptigen OCT image from a patient with multiple large drusen.

Condition
  • Drusen
Imaging Modality
  • OCT-Bioptigen
Fluorescein Angiography AOSLO Normal

Fluorescein Angiography AOSLO Normal

Fluorescein angiography image obtained using an adaptive optics scanning light ophthalmoscope, courtesy of Dr. Richard Rosen, New York Eye & Ear Infirmary.

Condition
  • Normal
Imaging Modality
  • Adaptive Optics - Angiography
Fovea variation OCT

Fovea variation OCT

OCT B-scans (left) and topographical thickness maps (right) showing the normal variability in the size and shape of the foveal pit.

Condition
  • Normal
Imaging Modality
  • OCT-Cirrus
LIAVA AOSLO

LIAVA AOSLO

Image of the parafoveal photoreceptor mosaic in a patient with red-green color blindness due to a specific mutation in the L/M opsin genes (LIAVA).

Condition
  • Color Blindness
Imaging Modality
  • Adaptive Optics
MacHole postop OCT

MacHole postop OCT

OCT B-scan from a patient 9 months following successful macular hole surgery.

Condition
  • MacHole postop
Imaging Modality
  • OCT-Bioptigen
Normal vessels, retinal function imager (RFI)

Normal vessels, retinal function imager (RFI)

Retinal vascular map obtained from the retinal function imager (RFI) from a healthy retina.

Condition
  • Normal
Imaging Modality
  • Motion contrast – RFI
Adaptive optics, confocal and split-detector photoreceptor mosaic

Normal-25-um-scalebar.jpg

Adaptive optics confocal image (left) and split-detector image (right) of the photoreceptor inner segment mosaic acquired at 10° of visual angle from fixation in a healthy volunteer. Scale bar 25µm

Condition
  • Normal
Imaging Modality
  • Adaptive Optics
Color fundus - optos ocular albinism

OcularAlbinismOptos.jpg

Color fundus - Optos image from a patient with ocular albinism.

Condition
  • Albinism
Imaging Modality
  • Color Fundus - Optos

parkinsonsfundus1.jpg

Color fundus - Visucam image from a patient with Parkinson's disease.

Condition
  • Parkinson's Disease
Imaging Modality
  • Color Fundus - Visucam

parkinsonsOCT1.jpg

OCT - Bioptigen image from patient with Parkinson's disease.

Condition
  • Parkinson's Disease
Imaging Modality
  • OCT-Bioptigen
Retinitis Pigmentosa (RP) CME OCT

Retinitis Pigmentosa (RP) CME OCT

Bioptigen OCT image showing CME in a patient with retinitis pigmentosa (RP).

Condition
  • Retinitis Pigmentosa
Imaging Modality
  • OCT-Bioptigen
Retinitis Pigmentosa Adaptive Optics

Retinitis Pigmentosa Adaptive Optics

The bubbled appearance of the top image (AO image of the photoreceptor mosaic) is caused by the presence of numerous cystic structures in the inner retina (seen in the lower OCT image).

Condition
  • Retinitis Pigmentosa
Imaging Modality
  • Adaptive Optics
  • Multimodal
  • OCT-Bioptigen
Retinitis Pigmentosa FAF Optos

Retinitis Pigmentosa FAF Optos

Wide-field autofluorescence image from a patient with retinitis pigmentosa obtained using the Optos imaging system.

Condition
  • Retinitis Pigmentosa
Imaging Modality
  • Autofluorescence - Optos
Retinitis Pigmentosa fundus optos

Retinitis Pigmentosa fundus optos

Wide-field fundus image from a patient with retinitis pigmentosa obtained using the Optos imaging system.

Condition
  • Retinitis Pigmentosa
Imaging Modality
  • Color Fundus - Optos

stargardtsAF1.jpg

Autofluorescence - Spectralis image from a patient with Stargardt disease.

Condition
  • Stargardt Disease
Imaging Modality
  • Autofluorescence - Spectralis

stargardtsAF2.jpg

Autofluorescence - Spectralis image from a patient with Stargardt disease.

Condition
  • Stargardt Disease
Imaging Modality
  • Autofluorescence - Spectralis

stargardtsOCT1.jpg

OCT - Bioptigen image from a patient with Stargardt disease.

Condition
  • Stargardt Disease
Imaging Modality
  • OCT-Bioptigen

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