About the Adult Echocardiography Core
Consultation services are provided by one of two board-certified cardiologists with extensive backgrounds in cardiac imaging and clinical research. As one of the largest medical research facilities in Wisconsin, we are able to offer a wide range of expertise in cardiac and vascular imaging. The Interim Director of the Echo Core Lab, Jennifer Strande, MD, PhD provides consultation with investigators to optimize the acquisition of data and provide qualitative and quantitative results for a clinical trial or research study while maintaining compliance with regulatory guidelines.
Echocardiography is the cornerstone of the cardiovascular structure and hemodynamic assessment. Its highly versatile nature makes it the non-invasive tool of choice. This form of non-invasive assessment is ideal for performing serial evaluations of cardiac function or real-time monitoring during and after pharmacological or therapeutic intervention. Echocardiography has the versatility that allows for rapid and comprehensive evaluation of cardiac structure, myocardial function, valvular hemodynamics and vascular structure. Protocols are adaptable to the needs of the investigator.
Compliance, Confidentiality and Quality Assurance
All Core Lab studies follow the American Society of Echocardiography (ASE) Recommendations for the use of Echocardiography in Clinical Trials (JASE, 2004; 17:1086-1119) and the ASE Standards for Echocardiography Core Laboratories (JASE, 2009; 22:755-765.)
Standard Operating Procedures and protocols are unique to every study. Imaging protocols are developed upon consultation with the Principal Investigator or in accordance with sponsor written protocols.
A dedicated scanning room for all ultrasound studies to ensure subject comfort and privacy is located in the Specialty Clinics Building on the Medical College of Wisconsin/Froedtert Health Campus. In addition, a state-of-the-art Xcelera workstation is used for image analysis. This system allows import of DICOM compatible data and performs advanced imaging analysis such as: 3D, Advanced 3D Quantification, 2D and Doppler Strain and IMT.
To maintain confidentiality, subject records/data are stored in a locked cabinet in the Echo Core Lab office and on Medical College of Wisconsin Corporate password protected computers. Only investigators and study staff identified on an approved Institutional Review Board protocol are authorized access to study specific documents and data.
All ultrasound studies are preliminarily reviewed by a Registered Diagnostic Cardiac Sonographer with the final interpretation made by a board certified Cardiologist to ensure accuracy of the final report. We are able to provide blinded analysis for your study.