Allergy, Asthma and Clinical Immunology

Recent Publications

Abstracts

• Chen X, Leach D, Ehlenbach SJ, Grayson MH.  Role of lamina propria dendritic cells in translating murine norovirus infection into atopic disease. [Abstract].  J Allergy Clin Immunol.  2010; 125(2):AB193.
   
• Shakir E, Ehlenbach SJ, Grayson MH. Decay of FcεRI expression on murine lung conventional dendritic cells. [Abstract].  J Allergy Clin Immunol.  2010; 125(2):AB228.
   
• Vasudev M, Pincsak H, Dasu T, Schauer DW, Grayson MH. Developmental expression of FcεRI on human peripheral blood dendritic cell subsets. [Abstract].  J Allergy Clin Immunol.  2010; 125(2):AB228.
   
• Cheung DS, Ehlenbach SJ, Grayson MH. Neutrophil mediated upregulation of FcεRI on conventional dendritic cells is type I interferon dependent. [Abstract].  J Allergy Clin Immunol.  2010; 125(2):AB238.
   
• Cheung DS, Ehlenbach SJ, Grayson MH. Induction of the high-affinity receptor for IgE (FcεRI) on lung conventional dendritic cells by CD49d+ neutrophils is CD11b dependent. [Abstract].  Am J Respir Crit Care Med.  2010; 181:A3780.

Manuscripts

• Grayson MH.  Lung dendritic cells and the inflammatory response.  Ann Allergy Asthma Immunol.  2006; 96:643-652.
   
• Grayson MH, Holtzman MJ.  Emerging role of dendritic cells in respiratory viral infection.  J Mol Med.  2007;85(10):1057-68.
   
• Grayson MH, Ramos MS, Rohlfing MM, Kitchens R, Wang HD, Gould A, Agapov E, Holtzman MJ.  Controls for lung dendritic cell maturation and migration during respiratory viral infection.  J Immunol.  2007;179(3):1438-48.
   
• Grayson MH, Cheung D, Rohlfing MM, Kitchens R, Spiegel DE, Tucker J, Battaile JT, Alevy Y, Yan L, Agapov E, Kim EY, Holtzman MJ.  Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia.  J Exp Med.  2007;204(11):2759-2769.
   
• Akk A, Simmons PM, Chan H, Agapov E, Holtzman MJ, Grayson MH, Pham CTN.  Dipeptidyl peptidase I (DPPI)-dependent neutrophil recruitment modulates the inflammatory response to Sendai virus infection.  J Immunol.  2008;180:3535-3542.
   
• Silver E, Yin-DeClue H, Schechtman KB, Grayson MH, Bacharier LB, Castro M.  Lower levels of plasmacytoid dendritic cells in peripheral blood are associated with a diagnosis of asthma 6 years after severe respiratory syncytial virus bronchiolitis.  Pediatr Allergy Immunol.  2008.  Dec. 8.  DOI: 10.1111/j.1399-3038.2008.00818.x.
   
• Kim EY, Battaile JT, Patel AC, You Y, Agapov E, Grayson MH, Benoit L, Byers D, Alevy Y, Tucker J, Swanson S, Tidwell R, Tyner JW, Morton JD, Castro M, Polenini D, Patterson GA, Schwendener RA, Allard JD, Peltz G, Holtzman MJ.  Persistent activation of an innate NKT cell-macrophage immune axis translates respiratory viral infection into chronic inflammatory lung disease.  Nat Med.  2008;14:633-640.
   
• Park SS, Ehlenbach SJ, Grayson MH.  Lung dendritic cells and IgE: the link between virus and atopy.  Future Microbiol.  2008;3:241-245.
   
• Zindl CL, Kim TH, Zeng M, Archambault AS, Grayson MH, Choi K, Schreiber RD, Chaplin DD.  The lymphotoxin LTα₁β₂ controls postnatal and adult spleen marginal sinus vascular structure and function.  Immunity.  2009;30:408-420.
   
• Holtzman MJ, Byers DE, Benoit LA, Battaile JT, You Y, Agapov E, Park C, Grayson MH, Kim EY, Patel AC.  Immune pathways for translating viral infection into chronic airway disease.  Adv Immunol.  2009;102:245-276.
   
• Kumar A, Grayson MH.  The role of viruses in the development and exacerbation of atopic disease.  Ann Allergy Asthma Immunol.  2009;103:181-187.

• Hayat Khan S, Grayson MH. Cross-linking IgE augments human conventional dendritic cell production of CCL28.  J Allergy Clin Immunol.  2010;125:265-267.

• Shakir EM, Grayson MH. The mannose-binding lectin gene in Atopic Dermatitis:  lessons from genetics.  Ann Allergy Asthma Immunol.  2010;105:1-2.

• Cheung DS, Ehlenbach SJ, Kitchens RT, Riley DA, Thomas LL, Holtzman MJ, Grayson MH.  Cutting edge:  CD49d+ neutrophils induce FcεRI expression on lung dendritic cells in a mouse model of postviral asthma.  J Immunol.  2010.  In press.

• Shakir EM, Cheung DS, Grayson MH.  Mechanisms of immunotherapy: a historical perspective.  Ann Allergy Asthma Immunol.  2010.  In press.

• Cheung DS, Ehlenbach SJ, Kitchens T, Riley DA, Grayson MH.  Development of atopy: severe paramyxoviral infection is sufficient to induce atopic disease against non-viral antigens in a mouse model.  Ann Allergy Asthma Immunol.  2010.  In press.

Click here for Grayson Lab Publications on PubMed