Human Molecular Genetics Center
The Human and Molecular Genetics Center at the Medical College of Wisconsin provides academic support for researchers at MCW who use the genomic sequence to understand disease and translate this information from the laboratory to the patient. Most of the research projects in the Center are funded by government agencies such as the National Institutes of Health. The research areas include various directions in genomics, high throughput sequencing and the development and use of single nucleotide polymorphisms (SNP's), microarray analysis and bioinformatics. Professor Tao Wang is associated with this Center.
Adamovic T, McAllister D, Wang T, Adamovic D, Rowe JJ, Moreno C, Lazar J, Jacob HJ, and Sugg SL, Identification of novel carcinogen-mediated mammary tumor susceptibility loci in the rat using the chromosome substitution technique, Genes, Chromosomes, and Cancer; 49(11):1035-45, 2010. PMC2943010
Grossberg S, Ogar J, Grossberg L, Gehcham A, and Klein JP, Frequency and magnitude of interferon β neutralizing antibodies in the evaluation of interferon β immunogenicity in multiple sclerosis patients, Journal of Interferon and Cytokine Research, 31 (3):337-44, 2011.
Klinker MW, Schiller JJ, Magnuson VL, Wang T, Basken J, Veth K, Pearce KI, Kinnunen L, Harjutsalo V, Wang X, Tuomilehto J, Sarti C, and Ghosh S, Single-nucleotide polymorphisms in the IL2RA gene are associated with age at diagnosis in late-onset Finnish type 1 diabetes subjects, Immunogenetics; 62(2):101-7, 2010.
Wang T, Jacob H, Ghosh S, Wang XJ and Zeng ZB, A joint association test for multiple SNPs in genetic case-control studies, Genetic Epidemiology; 33(2):151-163, 2009.
Wang T and Zeng ZB, Contribution of genetic effects to genetic variance components with epistasis and linkage disequilibrium, BMC Genet; 10(1):52, 2009.
Adamovic T, McAllister D, Rowe J, Wang T, Jacob HJ and Sugg SL, Genetic identification of loci controlling mammary tumor latency and multiplicity on chromosome 10 by direct physical mapping using a novel chemically induced SS/BN consomic rat model, Cancer Genetics and Cytogenetics; 186(1):41-48, 2008.