Cardiovascular Center

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Healing Begins with Discovery

Pushing the frontiers of research to help those who suffer

The following medical advances were discovered by Medical College of Wisconsin cardiovascular researchers:

Discovered substances produced by brain cells to trigger the growth of new blood vessels, an important clue as to how the brain works to combat the effects of a stroke.

Discovered how the body's reflexes control the heart and lung systems making general anesthesia safer.

Discovered the critical link between kidney blood flow regulation and the development of high blood pressure.

Discovered that female athletes experiencing amenorrhea (cessation of menstrual cycle) are at high risk for both cardiovascular disease and osteoporosis.

Discovered that automated external defibrillators, used in conjunction with cardiopulmonary resuscitation, double the chances of survival for cardiac arrest victims.

Discovered a gene that helps regulate triglyceride levels in the body. Elevated triglycerides, a fat component in the blood, are a significant risk factor in heart disease.

Discovered techniques used during surgery and after surgery that resulted in the nation's best outcomes for a form of pediatric heart surgery (hypoplastic left heart syndrome surgery).

Discovered higher levels of the hormone aldosterone in African Americans with high blood pressure. Aldosterone is secreted by the adrenal glands and causes salt retention by the kidneys.

Discovered that the transfer of the renin gene from a strain of rat resistant to hypertension into the genetic background of a hypertensive strain restores the relaxation of cerebral arteries.

Discovered novel genetic variants contributing to left ventricular hypertrophy in hypertensive individuals.

Discovered a way to create the first genetically modified rat using technology known as zinc finger nuclease, paving the way for the development of novel genetically modified animal models of human diseases.

Discovered that genes partially govern where the fatty deposits develop within the heart's arteries in patients.
© 2014 Medical College of Wisconsin
Page Updated 06/18/2014