Katherine Zappia

Katherine_ZappiaGraduate Student
Medical College of Wisconsin
Department of Cell Biology, Neurobiology & Anatomy
8701 Watertown Plank Road
Milwaukee, WI 53226-3548

(414) 955-8478
(414) 955-6517 (fax)

BS, Skidmore College, 2009

Faculty Advisor: Cheryl L. Stucky, PhD

Research Area: Pain and hypersensitivity in sickle cell disease

Overall, the Stucky lab studies mechanisms underlying pain and sensation, essentially how we sense the world around us. My current work is centered on sickle cell disease, a genetic disorder that causes red blood cells become rigid and fragile, and can sometimes block blood flow to tissues, causing a painful sickling crisis. In addition to these very painful crises, individuals with sickle cell disease often also have chronic pain. I am particularly interested in how the immune system interacts with the nervous system. Specifically, immune mediators appear to sensitize peripheral sensory neurons, leading to the development of chronic pain in sickle cell disease. Our goal is that understanding mechanisms driving this chronic pain may lead to novel or improved pain treatments.

Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226
(414) 955-8296
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