Medical College of Wisconsin
Department of Cell Biology, Neurobiology & Anatomy
8701 Watertown Plank Road
Milwaukee, WI 53226-3548
(414) 937-6284 (fax)
BS, Molecular Biology, University of Wisconsin-Madison, 2010
Faculty Advisor: Sridhar Rao, MD, PhD
Research Area: Stem cell transcriptional regulation, epigenetics, hematopoiesis
As an undergraduate with an interest in developmental biology, I joined a research lab that studies the spatio-temporal transcriptional regulatory properties that control floral patterning in developing flower buds. After graduation, I enriched my research experience by studying a human induced pluripotent stem cell (iPSC) model at MCW. In Dr. John Lough’s lab, I induced cardiomyogenesis in human iPSCs based on our understanding of in vivo cardiac development. Our goal was to identify the earliest lineage specific cardiogenic markers. I rapidly developed an interest using transcription factor markers to map cell fate. As a MSTP student in the Rao lab, I’m currently unifying my expanding interests in stem cells and transcriptional regulation and studying them in clinically relevant model. Specifically, we are interested in a class of non-coding RNAs, enhancer transcribed RNAs (eRNA), and delineating their role in lineage specific gene expression during hematopoietic commitment of pluripotent stem cells.
In sum, I continue to admire the genetic complexities that make a flower beautiful, yet I very much want to use this knowledge and insight to help us better understand human biology and to improve human health.