Associate Professor Department of Biophysics
Department of Biophysics Medical College of Wisconsin 8701 Watertown Plank Road Milwaukee, WI 53226-0509 Phone: 414-456-8095 Fax: 414-456-6512 Email: jvvivar@mcw.edu
Publications
Education University of Concepción, Concepción, Chile, Biochemistry (1988) University of São Paulo, São Paulo, Brazil Ph.D. in Biochemistry (1992) University of São Paulo, São Paulo, Postdoctoral Fellow in (1993-1996) Medical College of Wisconsin, Milwaukee, Postdoctoral Fellow, Department of Pathology (1996-1998)
Grants: Superoxide Generation from eNOS- The Role of Pterins is a four-year first renewal, $1.2 million award from the National Institute of Heart Lung Blood Institute to study the molecular mechanisms causing loss of NO production in the endothelium in conditions associated with increased lipid peroxidation. Tetrahydrobiopterin in Hypoxia-Ischemia Induced Fetal Brain Dysfunction is a R21, $375,000 award from the National Institute of Neurological Disorders and Stroke to study the link between hypoxia-ischemia or low oxygen supply and loss of tetrahydrobiopterin in the immature brain. Tetrahydrobiopterin is a key compound regulating several brain functions. This study will generate important information regarding the application of tetrahydrobiopterin in preventing fetal brain damage.
Research Interests: ● Superoxide generation from eNOS ● Regulation of NO production in the heart ● Tetrahydrobiopterin in fetal brain development
Research team: Jennifer Whitsett, Senior Research Technologist David Suster, Research Technologist