Small Animal Echocardiography Core Facility

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Diastolic Analysis

We routinely assess LV diastolic function in small animals based on three Doppler-derived parameters: E/E’, Vp, and IVRT/RR. Another index is E/A; however, distinct E and A peaks are generally not discernible in anesthetized rodents.

Pulsed wave Doppler Mitral Inflow Tissue Doppler Mitral Anulus
Doppler of Normal Mitral Valve Inflow Tissue Doppler of Mitral Annular Velocities
 Velocity of Propagation  IVRT
Color M-mode of Mitral Velocity of Propagation (Vp) Example of Isovolumic Relaxation Time
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Page Updated 01/09/2014