Small Animal Echocardiography Core Facility

Diastolic Analysis

We routinely assess LV diastolic function in small animals based on three Doppler-derived parameters: E/E’, Vp, and IVRT/RR. Another index is E/A; however, distinct E and A peaks are generally not discernible in anesthetized rodents.

Doppler of Normal Mitral Valve Inflow	Tissue Doppler of Mitral Annular Velocities
Color M-mode of Mitral Velocity of Propagation (Vp)	Example of Isovolumic Relaxation Time