Matthew Riese, M.D., Ph.D.
Assistant Professor of Medicine
Matthew Riese, M.D., Ph.D., is an Assistant Professor of Medicine, in the Division of Hematology and Oncology, Department of Medicine at the Medical College of Wisconsin. Dr. Riese graduated with M.D and Ph.D. degrees from the Medical College of Wisconsin in 2004 and then completed an internship and residency in internal medicine at Brigham and Women’s Hospital at Harvard Medical School in Boston, Massachusetts. He went on to complete a fellowship in hematology/oncology at the University of Pennsylvania in Philadelphia, Pennsylvania. Dr. Riese is board certified in Internal Medicine and Medical Oncology. He has authored numerous manuscripts and maintains an active research lab focused on augmenting immune-based therapies in the treatment of malignancy. Dr. Riese is interested in investigating immune therapies for genitourinary cancers. He specializes in the treatment of genitourinary malignancies at Froedtert Hospital.
PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation.
Bobrovnikova-Marjon E, Pytel D, Riese MJ, Vaites LP, Singh N, Koretzky GA, Witze ES, Diehl JA.
Mol Cell Biol. 2012 Jun;32(12):2268-78.
Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses.
Wu GF, Corbo E, Schmidt M, Smith-Garvin JE, Riese MJ, Jordan MS, Laufer TM, Brown EJ, Maltzman JS.
Eur J Immunol. 2011 Jul;41(7):2064-73. doi: 10.1002/eji.201040809. Epub 2011 Jun 7.
Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses.
Riese MJ, Grewal J, Das J, Zou T, Patil V, Chakraborty AK, Koretzky GA.
J Biol Chem. 2011 Feb 18;286(7):5254-65. Epub 2010 Dec 7.
Chemotherapy for patients with poor prognosis germ cell tumors.
Riese MJ, Vaughn DJ.
World J Urol. 2009 Aug;27(4):471-6. Epub 2009 Mar 28. Review.
Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.
Janzen V, Fleming HE, Riedt T, Karlsson G, Riese MJ, Lo Celso C, Reynolds G, Milne CD, Paige CJ, Karlsson S, Woo M, Scadden DT.
Cell Stem Cell. 2008 Jun 5;2(6):584-94.