MCW Biophysics News

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MCW researchers report potential mitochondrial drug therapy for pancreatic cancer

May 26 - Balaraman Kalyanaraman, PhD, chairman and professor of biophysics and Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research; Michael B. Dwinell, PhD, professor of microbiology and molecular genetics; and their international research team published an article in Cancer Research that describes a new redox-sensitive, mitochondrial-energy-sensor-mediated pathway of regression of pancreatic cancer cell growth.

Medical College of Wisconsin receives $5.5 million grant to study Alzheimer’s disease

May 2 - The Medical College of Wisconsin (MCW), in collaboration with the University of Wisconsin-Madison (UW-Madison), has received a four-year, $5.5 million grant from the National Institutes of Health’s (NIH) National Institute on Aging to study Alzheimer’s disease. The study, called the Alzheimer’s Disease Connectome Project, will use the Human Connectome Project approach, which is aimed at constructing a map of the neural connections within and across individuals, to perform brain imaging on 300 elderly individuals.

Wisconsin researchers land NIH dementia grant

Apr. 28 - Researchers at the Medical College of Wisconsin and the University of Wisconsin- Madison have received a four-year, $5.5 million grant to better understand how communication between parts of the brain changes as the result of normal aging or of dementia. Milwaukee Journal Sentinel

Dr. Balaraman Kalyanaraman co-authors paper on potential Parkinson’s disease treatment

Feb. 12 - Balaraman Kalyanaraman, PhD, chairman and professor of biophysics and Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research, co-authored a paper with Anumantha Kanthasamy, MS, MPhil, PhD, W.E. Lloyd Endowed Chair in Neurotoxicology and distinguished professor and chair of biomedical sciences at Iowa State University, in the Journal of Neuroimmune Pharmacology.

Biophysics researchers publish paper identifying novel inhibitors of NADPH oxidase enzymes

Feb. 11 - Drs. Balaraman Kalyanaraman, chairman and professor of biophysics and Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research, and Jacek Zielonka, research director of the Free Radical Research Center in the department of biophysics, recently published an article in the Journal of Biological Chemistry describing ways with which inhibitors of NADPH oxidase enzyme 2 (Nox2 isoform) are identified.

Drs. Candice Klug & Kathryn Schultz author paper published in Science

Feb. 9 - Candice Klug, PhD, professor of biophysics, and Kathryn Schultz, PhD, research scientist, are authors on a paper published in Science on Feb. 5 on the structure of a bacterial enzyme responsible for conferring resistance to polymyxin, an antibiotic used to treat infections. The paper represents collaborative research between MCW’s department of biophysics and Columbia University.

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