MCW Genetics News

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Marquette-Led Project Aims to Enhance Elder-Care Training for Health Professionals

Sept. 11 - Health Canal reports that MCW is a partner in the Marquette University-led GEAR UP (Geriatrics Equipped And Unsupervised Practice), a $2.55 million federally-funded project to enhance how Wisconsin health care professionals are trained to care for older adults. Other partners in the project are UW-Madison, Aurora Health Care, and the Southeastern Wisconsin chapter of the Alzheimer’s Association. Health Canal

Dr. Geurts is First Recipient of Steve Cullen Healthy Heart Scholar Award

Aug. 12 - Aron Geurts, PhD is the first recipient of the $25,000 Steve Cullen Healthy Heart Scholar Award. Dr. Geurts will use the scholarship funds in his accelerated efforts to model genetic variation in human stem cells which will lead to a better understanding of cardiovascular disease and new avenues for specific therapeutic approaches. The award is funded by proceeds from the annual Steve Cullen Healthy Heart Club Run/Walk. Lake Country Now

Workshop on genome resources for the rat community planned for Sept. 14-16

Aug. 11 - A three-day workshop on Genome Resources for the Rat Community will be held at the Medical College of Wisconsin on Monday, Sept. 14 – Wednesday, Sept. 16.

MCW physician/scientist receives grant to study graft versus host disease in hematopoietic stem cell transplant recipients

Aug. 10 - The Medical College of Wisconsin (MCW) has received a four-year $1.5 million grant from the National Institutes of Health’s (NIH) National Heart, Lung and Blood Institute to research the pathophysiology of graft versus host disease in allogeneic hematopoietic stem cell transplant recipients (HSCT).

MCW scientist to study novel regulatory mechanisms for a gene involved in vascular anomalies

Aug. 3 - The Medical College of Wisconsin (MCW) has received a four-year, $1.8 million dollar grant from the National Institutes of Health’s National Heart, Lung and Blood Institute to study the RNA regulatory mechanisms underlying genes involved in vascular anomalies.

Identical twins needed to study effects of genes and environment on blood pressure

July 29 - Froedtert Hospital and the Medical College of Wisconsin (MCW) are recruiting identical twins for a clinical study that will determine what kind of modifications to one’s genetic code would lead to higher blood pressures. Mingyu Liang, PhD, professor of Physiology, and Srividya Kidambi MD, assistant professor of Medicine at the Medical College of Wisconsin, are the lead investigators for the study.

Photo from Human and Molecular Genetics Center Illustrates Article on Research Funding

July 15 - The World Economic Forum Agenda uses a photo of scientists working in MCW’s Human and Molecular Genetics Center’s Sequencing Core to illustrate an article on which nations spend the most on research and development. Israel ranked first; the United States and Austria were tied for 11th place. World Economic Forum Agenda

Dr. Imig Expects Companies to Invest in Drugs Targeted to Gene Mutations

July 13 - John Imig, PhD, (Pharmacology & Toxicology) tells International Business Times that he expects the debut of the PCSK-9 inhibitors (which targets a mutation in the PCSK-9 gene, which causes high cholesterol) will spur companies to invest in this area as scientists continue their search for genetic factors underlying major diseases. International Business Times

Whole-Genome Sequencing First Done in Milwaukee Now Performed Nationwide

July 8 - An article in GEN magazine on the field of genetics notes that whole-genome sequencing was first successfully used at MCW in 2010, and that the procedure is now being used at pediatric hospitals nationwide. GEN Magazine

Family to Speak before Congress on Need for Special Needs Programs

June 15 - A Hales Corner family traveled to Washington, D.C., to speak before Congress on the need to fund child health and health care programs modeled on Children’s Hospital of Wisconsin’s special needs program. The family’s daughter was born with a genetic abnormality so rare that only three people in the world have the disorder. WISN

WBCS, Inc. to fund three breast cancer researchers

May 29 - Three researchers at the Medical College of Wisconsin (MCW) have each received a two-year, $100,000 grant from WBCS, Inc. (Wisconsin Breast Cancer Showhouse) to study cancer risks and potential new therapies.

MCW researcher to study gene therapies for hemophilia

May 26 - A researcher at the Medical College of Wisconsin (MCW) has received a four-year, $1.5 million dollar grant from the National Institutes of Health’s National Heart, Lung, and Blood Institute to continue her study of blood platelet gene therapies for hemophilia A, a genetic bleeding disorder.

MCW/VA collaborate on Million Veterans Program to determine how genetics impact health

May 20 - One large project aimed at helping improve Veterans’ health that involves Medical College of Wisconsin faculty is the Million Veterans Program (MVP). MVP is a national, voluntary program funded by the Department of Veterans Affairs aimed at determining how genetics impact health.

American Heart Association funds epigenetic hypertension research at MCW

May 19 - Diet and other lifestyle and environmental factors can change your genes, which could make you susceptible to high blood pressure, or hypertension, and could be inherited. Now, researchers and physicians at the Medical College of Wisconsin (MCW) are working to determine exactly how that happens—and why.

Dr. Flister Receives $1.75 Million NCI Grant to Study Factors that Impact Breast Cancer Risk

May 13 - Michael Flister, PhD, (Physiology) received a five-year, $1.75 million grant from the National Cancer Institute to identify factors in the microenvironment of tumors that impact breast cancer risk. The goal of this project is to develop a new genetic model to assess breast cancer risk in the tumor microenvironment. Milwaukee Journal Sentinel

Genetic mapping for breast cancer risk

May 6 - The Medical College of Wisconsin (MCW) has received a five-year, $1.75 million dollar grant from the National Institutes of Health’s National Cancer Institute to identify factors in the microenvironment of tumors that impact breast cancer risk.

Dr. Jacob Accepts Position with Alabama Biotechnology Institute

Apr. 16 - MCW said that it will continue its commitment to genomics and personalized medicine following the announcement that Howard Jacob, PhD, (Human & Molecular Genetics Center; Physiology) has accepted a position with HudsonAlpha Institute for Biotechnology in Alabama. Milwaukee Journal Sentinel, Milwaukee Business Journal, and WAAYTV.

Dr. Routes Provides Expert Comment on “Bubble Boy Disease”

Mar. 27 - Dr. John Routes provides expert comment to Today Health on severe combined immunodeficiency, also known as “bubble boy disease.” The disorder occurs in approximately 1 in 50,000 live births. Today

Experimental Treatment Saves Life of Newborn with Metabolic Disorder

Mar. 26 - A Milwaukee Journal Sentinel investigative report on delays in processing newborn screening tests notes that MCW /Children’s physicians used an experimental treatment to successfully save the life of newborn with a dangerous metabolic disorder. It was only the seventh time the treatment had been used worldwide. Milwaukee Journal Sentinel

What is the clinical value of DNA sequencing?

Mar. 19 - David Dimmock, associate professor of pediatrics (genetics) and a geneticist at Children’s Hospital of Wisconsin, discusses new recommendations suggested by the American College of Medical Genetics and Genomics to define the "clinical utility" of next generation sequencing. GenomeWeb

Dr. Jacob Discusses Value of Rat Genome Database to Biomedical Research

Mar. 3 - Howard Jacob, PhD, (Human & Molecular Genetics Center) discusses the importance of the Rat Genome Database for biomedical research in an interview with Wisconsin Public Radio. Dr. Jacob recently received a five-year, $8 million NIH renewal grant for the Rat Genome Database, housed at MCW. In 2014, 180,000 visits to the database were recorded by scientists worldwide. WPR

Rat Genome Database Receives $8 Million Renewal Grant

Feb. 23 - The Rat Genome Database, based at MCW, received a four-year, $8 million renewal grant from the National Heart, Lung and Blood Institute. Howard Jacob, PhD is primary investigator for the Rat Genome Database, which has received more than $35 million since 1999. In 2014, the database was accessed by more than 180,000 users in 190 countries. Milwaukee Journal Sentinel and Health News Digest

Dr. Derse Advises Caution, More Study before Allowing Three-Parent Babies

Feb. 18 - In an interview with the Milwaukee Journal Sentinel, Dr. Arthur Derse recommends caution and further study before human studies are conducted on genetic modification of human embryos, so-called three-parent babies. Milwaukee Journal Sentinel

MCW bioethicist discusses controversial “three-parent baby” proposal

Feb. 9 - Art Derse, MD, JD, professor of emergency medicine and director of the Center for Bioethics and Medical Humanities, says caution is warranted in Great Britain’s proposal to allow “three-parent babies” to be created. The controversial proposal involves genetic manipulation of eggs to eliminate mitochondrial disease from embryos before implantation. Milwaukee Journal Sentinel

Dr. Xiong Discovers Gene Associated with Lung Cancer

Feb. 3 - Donghai Xiong, PhD was lead author of a study published in the American Journal of Human Genetics that identified a gene associated with lung cancer. Milwaukee Journal Sentinel, Fox 6 Now and Science Daily

Cancer Center researchers link Parkinson’s gene to lung cancer

Jan. 29 - Donghai Xiong, PhD, assistant professor of pharmacology and toxicology at MCW; and Ming You, MD, PhD, the Joseph F. Heil Jr. Professor of Oncogenesis and Director of the Cancer Center, have linked a gene associated with Parkinson’s Disease to familial lung cancer. Milwaukee Journal Sentinel

Parkinson’s gene linked to lung cancer

Jan. 29 - Researchers at the Medical College of Wisconsin (MCW), in collaboration with other colleagues of the Genetic Epidemiology of Lung Cancer Consortium (GELCC), have identified a gene that is associated with lung cancer.

Milwaukee Journal Sentinel Cites Pioneering Work in Genome Sequencing

Dec. 11 - The Milwaukee Journal Sentinel reports that doctors at Children's Mercy Kansas City have found that genome sequencing can lead to the diagnosis of neurologic and developmental disorders. Milwaukee Journal Sentinel

Dr. Michael E. Mitchell Named 2014 Health Care Hero

Nov. 25 - Milwaukee BizTimes named Dr. Michael E. Mitchell as a 2014 Health Care Hero in the category of Advancements in Health Care. Biz Times

Dr. Strong Discusses Ethical Issues Related to Genetic Information

Oct. 15 - Kimberly Strong, PhD provides expert comment to Genetic Engineering & Biotechnology News on ethical issues related to the scope and scale of genetic information that should be shared with patients and others. Genetic Engineering and Biotechnology News

MCW Part of University of Chicago-Led Consortium Studying Drug Abuse-Associated Behaviors

Oct. 15 - MCW is a collaborating partner in a new University of Chicago-led consortium studying drug abuse.

Dr. Prokop Receives Grant through NIH’s “Big Data to Knowledge” Project

Oct. 14 - MCW is one of more than two dozen institutions receiving NIH grants through the Big Data to Knowledge project. Wauwatosa Now and The Chronicle of Higher Education

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Page Updated 10/05/2014