Nov. 17 - A group of researchers led by Mayo Clinic has discovered that disclosing genetic risk for coronary heart disease (CHD) results in lower low-density lipoprotein cholesterol (LDL), also known as bad cholesterol. Dr. Broeckel is listed as a co-author. Science Daily
Nov. 3 - Mark Johnson and Kathleen Gallagher provide a follow up on Nic Volker, one of the first patients in the world to be saved by DNA sequencing. Milwaukee Journal Sentinel
Oct. 15 - Medical College of Wisconsin (MCW) biotech spin-off company, Protein Foundry LLC, has received an 18 month, $250,000 Small Business Innovation Research Contract (SBIR) from the National Institutes of Health National Heart, Lung and Blood Institute. This contract supports a collaborative project with Joseph T. Barbieri, PhD, professor and interim chair of microbiology and molecular genetics at MCW, to develop a safe and efficient method to deliver therapeutic proteins into nerve cells.
Sept. 11 - Health Canal reports that MCW is a partner in the Marquette University-led GEAR UP (Geriatrics Equipped And Unsupervised Practice), a $2.55 million federally-funded project to enhance how Wisconsin health care professionals are trained to care for older adults. Other partners in the project are UW-Madison, Aurora Health Care, and the Southeastern Wisconsin chapter of the Alzheimer’s Association. Health Canal
Aug. 12 - Aron Geurts, PhD is the first recipient of the $25,000 Steve Cullen Healthy Heart Scholar Award. Dr. Geurts will use the scholarship funds in his accelerated efforts to model genetic variation in human stem cells which will lead to a better understanding of cardiovascular disease and new avenues for specific therapeutic approaches. The award is funded by proceeds from the annual Steve Cullen Healthy Heart Club Run/Walk. Lake Country Now
Aug. 11 - A three-day workshop on Genome Resources for the Rat Community will be held at the Medical College of Wisconsin on Monday, Sept. 14 – Wednesday, Sept. 16.
Aug. 10 - The Medical College of Wisconsin (MCW) has received a four-year $1.5 million grant from the National Institutes of Health’s (NIH) National Heart, Lung and Blood Institute to research the pathophysiology of graft versus host disease in allogeneic hematopoietic stem cell transplant recipients (HSCT).
Aug. 3 - The Medical College of Wisconsin (MCW) has received a four-year, $1.8 million dollar grant from the National Institutes of Health’s National Heart, Lung and Blood Institute to study the RNA regulatory mechanisms underlying genes involved in vascular anomalies.
July 29 - Froedtert Hospital and the Medical College of Wisconsin (MCW) are recruiting identical twins for a clinical study that will determine what kind of modifications to one’s genetic code would lead to higher blood pressures. Mingyu Liang, PhD, professor of Physiology, and Srividya Kidambi MD, assistant professor of Medicine at the Medical College of Wisconsin, are the lead investigators for the study.
July 15 - The World Economic Forum Agenda uses a photo of scientists working in MCW’s Human and Molecular Genetics Center’s Sequencing Core to illustrate an article on which nations spend the most on research and development. Israel ranked first; the United States and Austria were tied for 11th place. World Economic Forum Agenda
July 13 - John Imig, PhD, (Pharmacology & Toxicology) tells International Business Times that he expects the debut of the PCSK-9 inhibitors (which targets a mutation in the PCSK-9 gene, which causes high cholesterol) will spur companies to invest in this area as scientists continue their search for genetic factors underlying major diseases. International Business Times
July 8 - An article in GEN magazine on the field of genetics notes that whole-genome sequencing was first successfully used at MCW in 2010, and that the procedure is now being used at pediatric hospitals nationwide. GEN Magazine
June 15 - A Hales Corner family traveled to Washington, D.C., to speak before Congress on the need to fund child health and health care programs modeled on Children’s Hospital of Wisconsin’s special needs program. The family’s daughter was born with a genetic abnormality so rare that only three people in the world have the disorder. WISN
May 29 - Three researchers at the Medical College of Wisconsin (MCW) have each received a two-year, $100,000 grant from WBCS, Inc. (Wisconsin Breast Cancer Showhouse) to study cancer risks and potential new therapies.
May 26 - A researcher at the Medical College of Wisconsin (MCW) has received a four-year, $1.5 million dollar grant from the National Institutes of Health’s National Heart, Lung, and Blood Institute to continue her study of blood platelet gene therapies for hemophilia A, a genetic bleeding disorder.
May 20 - One large project aimed at helping improve Veterans’ health that involves Medical College of Wisconsin faculty is the Million Veterans Program (MVP). MVP is a national, voluntary program funded by the Department of Veterans Affairs aimed at determining how genetics impact health.
May 19 - Diet and other lifestyle and environmental factors can change your genes, which could make you susceptible to high blood pressure, or hypertension, and could be inherited. Now, researchers and physicians at the Medical College of Wisconsin (MCW) are working to determine exactly how that happens—and why.
May 13 - Michael Flister, PhD, (Physiology) received a five-year, $1.75 million grant from the National Cancer Institute to identify factors in the microenvironment of tumors that impact breast cancer risk. The goal of this project is to develop a new genetic model to assess breast cancer risk in the tumor microenvironment. Milwaukee Journal Sentinel
May 6 - The Medical College of Wisconsin (MCW) has received a five-year, $1.75 million dollar grant from the National Institutes of Health’s National Cancer Institute to identify factors in the microenvironment of tumors that impact breast cancer risk.
Apr. 16 - MCW said that it will continue its commitment to genomics and personalized medicine following the announcement that Howard Jacob, PhD, (Human & Molecular Genetics Center; Physiology) has accepted a position with HudsonAlpha Institute for Biotechnology in Alabama. Milwaukee Journal Sentinel, Milwaukee Business Journal, AL.com and WAAYTV.
Mar. 27 - Dr. John Routes provides expert comment to Today Health on severe combined immunodeficiency, also known as “bubble boy disease.” The disorder occurs in approximately 1 in 50,000 live births. Today
Mar. 26 - A Milwaukee Journal Sentinel investigative report on delays in processing newborn screening tests notes that MCW /Children’s physicians used an experimental treatment to successfully save the life of newborn with a dangerous metabolic disorder. It was only the seventh time the treatment had been used worldwide. Milwaukee Journal Sentinel
Mar. 19 - David Dimmock, associate professor of pediatrics (genetics) and a geneticist at Children’s Hospital of Wisconsin, discusses new recommendations suggested by the American College of Medical Genetics and Genomics to define the "clinical utility" of next generation sequencing. GenomeWeb
Mar. 3 - Howard Jacob, PhD, (Human & Molecular Genetics Center) discusses the importance of the Rat Genome Database for biomedical research in an interview with Wisconsin Public Radio. Dr. Jacob recently received a five-year, $8 million NIH renewal grant for the Rat Genome Database, housed at MCW. In 2014, 180,000 visits to the database were recorded by scientists worldwide. WPR
Feb. 23 - The Rat Genome Database, based at MCW, received a four-year, $8 million renewal grant from the National Heart, Lung and Blood Institute. Howard Jacob, PhD is primary investigator for the Rat Genome Database, which has received more than $35 million since 1999. In 2014, the database was accessed by more than 180,000 users in 190 countries. Milwaukee Journal Sentinel and Health News Digest
Feb. 18 - In an interview with the Milwaukee Journal Sentinel, Dr. Arthur Derse recommends caution and further study before human studies are conducted on genetic modification of human embryos, so-called three-parent babies. Milwaukee Journal Sentinel
Feb. 9 - Art Derse, MD, JD, professor of emergency medicine and director of the Center for Bioethics and Medical Humanities, says caution is warranted in Great Britain’s proposal to allow “three-parent babies” to be created. The controversial proposal involves genetic manipulation of eggs to eliminate mitochondrial disease from embryos before implantation. Milwaukee Journal Sentinel
Feb. 3 - Donghai Xiong, PhD was lead author of a study published in the American Journal of Human Genetics that identified a gene associated with lung cancer.
Milwaukee Journal Sentinel, Fox 6 Now and Science Daily
Jan. 29 - Donghai Xiong, PhD, assistant professor of pharmacology and toxicology at MCW; and Ming You, MD, PhD, the Joseph F. Heil Jr. Professor of Oncogenesis and Director of the Cancer Center, have linked a gene associated with Parkinson’s Disease to familial lung cancer. Milwaukee Journal Sentinel
Jan. 29 - Researchers at the Medical College of Wisconsin (MCW), in collaboration with other colleagues of the Genetic Epidemiology of Lung Cancer Consortium (GELCC), have identified a gene that is associated with lung cancer.
Dec. 11 - The Milwaukee Journal Sentinel reports that doctors at Children's Mercy Kansas City have found that genome sequencing can lead to the diagnosis of neurologic and developmental disorders. Milwaukee Journal Sentinel
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