MCW Genetics News

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Photo from Human and Molecular Genetics Center Illustrates Article on Research Funding

July 15 - The World Economic Forum Agenda uses a photo of scientists working in MCW’s Human and Molecular Genetics Center’s Sequencing Core to illustrate an article on which nations spend the most on research and development. Israel ranked first; the United States and Austria were tied for 11th place. World Economic Forum Agenda

Identical twins needed to study effects of genes and environment on blood pressure

July 14 - Froedtert Hospital and the Medical College of Wisconsin (MCW) are recruiting identical twins for a clinical study that will determine what kind of modifications to one’s genetic code would lead to higher blood pressures. Mingyu Liang, PhD, professor of Physiology, and Srividya Kidambi MD, assistant professor of Medicine at the Medical College of Wisconsin, are the lead investigators for the study.

Dr. Imig Expects Companies to Invest in Drugs Targeted to Gene Mutations

July 13 - John Imig, PhD, (Pharmacology & Toxicology) tells International Business Times that he expects the debut of the PCSK-9 inhibitors (which targets a mutation in the PCSK-9 gene, which causes high cholesterol) will spur companies to invest in this area as scientists continue their search for genetic factors underlying major diseases. International Business Times

Whole-Genome Sequencing First Done in Milwaukee Now Performed Nationwide

July 8 - An article in GEN magazine on the field of genetics notes that whole-genome sequencing was first successfully used at MCW in 2010, and that the procedure is now being used at pediatric hospitals nationwide. GEN Magazine

Family to Speak before Congress on Need for Special Needs Programs

June 15 - A Hales Corner family traveled to Washington, D.C., to speak before Congress on the need to fund child health and health care programs modeled on Children’s Hospital of Wisconsin’s special needs program. The family’s daughter was born with a genetic abnormality so rare that only three people in the world have the disorder. WISN

WBCS, Inc. to fund three breast cancer researchers

May 29 - Three researchers at the Medical College of Wisconsin (MCW) have each received a two-year, $100,000 grant from WBCS, Inc. (Wisconsin Breast Cancer Showhouse) to study cancer risks and potential new therapies.

MCW researcher to study gene therapies for hemophilia

May 26 - A researcher at the Medical College of Wisconsin (MCW) has received a four-year, $1.5 million dollar grant from the National Institutes of Health’s National Heart, Lung, and Blood Institute to continue her study of blood platelet gene therapies for hemophilia A, a genetic bleeding disorder.

MCW/VA collaborate on Million Veterans Program to determine how genetics impact health

May 20 - One large project aimed at helping improve Veterans’ health that involves Medical College of Wisconsin faculty is the Million Veterans Program (MVP). MVP is a national, voluntary program funded by the Department of Veterans Affairs aimed at determining how genetics impact health.

American Heart Association funds epigenetic hypertension research at MCW

May 19 - Diet and other lifestyle and environmental factors can change your genes, which could make you susceptible to high blood pressure, or hypertension, and could be inherited. Now, researchers and physicians at the Medical College of Wisconsin (MCW) are working to determine exactly how that happens—and why.

Dr. Flister Receives $1.75 Million NCI Grant to Study Factors that Impact Breast Cancer Risk

May 13 - Michael Flister, PhD, (Physiology) received a five-year, $1.75 million grant from the National Cancer Institute to identify factors in the microenvironment of tumors that impact breast cancer risk. The goal of this project is to develop a new genetic model to assess breast cancer risk in the tumor microenvironment. Milwaukee Journal Sentinel

Genetic mapping for breast cancer risk

May 6 - The Medical College of Wisconsin (MCW) has received a five-year, $1.75 million dollar grant from the National Institutes of Health’s National Cancer Institute to identify factors in the microenvironment of tumors that impact breast cancer risk.

Dr. Jacob Accepts Position with Alabama Biotechnology Institute

Apr. 16 - MCW said that it will continue its commitment to genomics and personalized medicine following the announcement that Howard Jacob, PhD, (Human & Molecular Genetics Center; Physiology) has accepted a position with HudsonAlpha Institute for Biotechnology in Alabama. Milwaukee Journal Sentinel, Milwaukee Business Journal, and WAAYTV.

Dr. Routes Provides Expert Comment on “Bubble Boy Disease”

Mar. 27 - Dr. John Routes provides expert comment to Today Health on severe combined immunodeficiency, also known as “bubble boy disease.” The disorder occurs in approximately 1 in 50,000 live births. Today

Experimental Treatment Saves Life of Newborn with Metabolic Disorder

Mar. 26 - A Milwaukee Journal Sentinel investigative report on delays in processing newborn screening tests notes that MCW /Children’s physicians used an experimental treatment to successfully save the life of newborn with a dangerous metabolic disorder. It was only the seventh time the treatment had been used worldwide. Milwaukee Journal Sentinel

What is the clinical value of DNA sequencing?

Mar. 19 - David Dimmock, associate professor of pediatrics (genetics) and a geneticist at Children’s Hospital of Wisconsin, discusses new recommendations suggested by the American College of Medical Genetics and Genomics to define the "clinical utility" of next generation sequencing. GenomeWeb

Dr. Jacob Discusses Value of Rat Genome Database to Biomedical Research

Mar. 3 - Howard Jacob, PhD, (Human & Molecular Genetics Center) discusses the importance of the Rat Genome Database for biomedical research in an interview with Wisconsin Public Radio. Dr. Jacob recently received a five-year, $8 million NIH renewal grant for the Rat Genome Database, housed at MCW. In 2014, 180,000 visits to the database were recorded by scientists worldwide. WPR

Rat Genome Database Receives $8 Million Renewal Grant

Feb. 23 - The Rat Genome Database, based at MCW, received a four-year, $8 million renewal grant from the National Heart, Lung and Blood Institute. Howard Jacob, PhD is primary investigator for the Rat Genome Database, which has received more than $35 million since 1999. In 2014, the database was accessed by more than 180,000 users in 190 countries. Milwaukee Journal Sentinel and Health News Digest

Dr. Derse Advises Caution, More Study before Allowing Three-Parent Babies

Feb. 18 - In an interview with the Milwaukee Journal Sentinel, Dr. Arthur Derse recommends caution and further study before human studies are conducted on genetic modification of human embryos, so-called three-parent babies. Milwaukee Journal Sentinel

MCW bioethicist discusses controversial “three-parent baby” proposal

Feb. 9 - Art Derse, MD, JD, professor of emergency medicine and director of the Center for Bioethics and Medical Humanities, says caution is warranted in Great Britain’s proposal to allow “three-parent babies” to be created. The controversial proposal involves genetic manipulation of eggs to eliminate mitochondrial disease from embryos before implantation. Milwaukee Journal Sentinel

Dr. Xiong Discovers Gene Associated with Lung Cancer

Feb. 3 - Donghai Xiong, PhD was lead author of a study published in the American Journal of Human Genetics that identified a gene associated with lung cancer. Milwaukee Journal Sentinel, Fox 6 Now and Science Daily

Cancer Center researchers link Parkinson’s gene to lung cancer

Jan. 29 - Donghai Xiong, PhD, assistant professor of pharmacology and toxicology at MCW; and Ming You, MD, PhD, the Joseph F. Heil Jr. Professor of Oncogenesis and Director of the Cancer Center, have linked a gene associated with Parkinson’s Disease to familial lung cancer. Milwaukee Journal Sentinel

Parkinson’s gene linked to lung cancer

Jan. 29 - Researchers at the Medical College of Wisconsin (MCW), in collaboration with other colleagues of the Genetic Epidemiology of Lung Cancer Consortium (GELCC), have identified a gene that is associated with lung cancer.

Milwaukee Journal Sentinel Cites Pioneering Work in Genome Sequencing

Dec. 11 - The Milwaukee Journal Sentinel reports that doctors at Children's Mercy Kansas City have found that genome sequencing can lead to the diagnosis of neurologic and developmental disorders. Milwaukee Journal Sentinel

Dr. Michael E. Mitchell Named 2014 Health Care Hero

Nov. 25 - Milwaukee BizTimes named Dr. Michael E. Mitchell as a 2014 Health Care Hero in the category of Advancements in Health Care. Biz Times

Dr. Strong Discusses Ethical Issues Related to Genetic Information

Oct. 15 - Kimberly Strong, PhD provides expert comment to Genetic Engineering & Biotechnology News on ethical issues related to the scope and scale of genetic information that should be shared with patients and others. Genetic Engineering and Biotechnology News

MCW Part of University of Chicago-Led Consortium Studying Drug Abuse-Associated Behaviors

Oct. 15 - MCW is a collaborating partner in a new University of Chicago-led consortium studying drug abuse.

Dr. Prokop Receives Grant through NIH’s “Big Data to Knowledge” Project

Oct. 14 - MCW is one of more than two dozen institutions receiving NIH grants through the Big Data to Knowledge project. Wauwatosa Now and The Chronicle of Higher Education

MCW researcher receives funding from new “Big Data to Knowledge” initiative

Oct. 9 - The Medical College of Wisconsin (MCW) has received a five-year, $500,000 training grant from the National Institutes of Health’s (NIH) National Institute of Environmental Health Sciences to investigate the development of a tool to interpret the genetic data of humans affected with cardiovascular disease.

Editorial Cites Pioneering Work in Genome Sequencing

Oct. 8 - An editorial in Genetic Engineering & Biotechnology News discusses a presentation by Howard Jacob, PhD on MCW/Children’s Hospital of Wisconsin’s pioneering work in genome sequencing. Genetic Engineering and Biotechnology News

Human & Molecular Genetics Center Awarded $2.5 Million NIH Grant for Genome Sequencing

Oct. 7 - The NIH awarded a four-year, $2.5 million to MCW’s Human & Molecular Genetics Center and Illumina, Inc., to become one of two national centers to sequence the genomes of 1,625 patients and their families in the federal government’s Undiagnosed Disease Network. Milwaukee Journal Sentinel, GM Today, WISN and

Dr. Geurts to Discuss Engineered Proteins to Modify Animal Genomes

Oct. 2 - The Clinical and Translational Science Institute of Southeast Wisconsin announced upcoming free programs for its Science Cafés series to be held on the UWM Innovation Campus. Wauwatosa Now and Wauwatosa Now

Human and Molecular Genetics Center selected to run Undiagnosed Disease Network sequencing center

Sept. 29 - The Human and Molecular Genetics Center (HMGC) at the Medical College of Wisconsin (MCW), in collaboration with Illumina, has been selected as one of two National Institutes of Health genomic sequencing sites for the Undiagnosed Disease Network (UDN). The UDN was created to use DNA sequencing and other strategies to advance laboratory and clinical research and to aid in the diagnosis and treatment of patients with rare diseases.

Yale Genome Sequencing Study Builds on MCW’s Pioneering Research

The Milwaukee Journal Sentinel reports on a Yale University School of Medicine study published in Nature Genetics on the use of genome sequencing to diagnose a baffling disease that killed an infant, but saved his father and brother. Milwaukee Journal Sentinel

Dr. Woods Identifies New Gene Associated with Traits Involved in Diabetes

Sept. 22 - In a study published in Genetics, Leah Solberg Woods, PhD and colleagues reported that they had has identified a new gene associated with fasting glucose and insulin levels in rats, mice and in humans; traits involved in diabetes. Nature World News, Health Canal, Medical Xpress and Bio-Medicine

Drug discovery and genetic engineering: Science Café series scheduled

Sept. 19 - The Community Engagement program of the Clinical and Translational Science Institute of Southeast Wisconsin will hold a series of Science Cafés at the UWM Innovation Campus that are free and open to the public. Topics will include the drug discovery process and information about therapeutic targets, genomics, and genetic engineering. Each café will run from 6:00 – 7:30 p.m.

Researchers discover new gene responsible for traits involved in diabetes

Sept. 18 - A collaborative research team led by Medical College of Wisconsin scientists has identified a new gene associated with fasting glucose and insulin levels in rats, mice and in humans. The findings are published in the September issue of Genetics.

Dr. Broeckel Calls CDI Stem Cell Automation Process as Major Advancement

Sept. 03 - The Milwaukee Journal Sentinel reports that Cellular Dynamics International (CDI) in Madison received a U.S. patent on the automated production of cells that can be grown into any of the more than 200 types of cells in the body. Milwaukee Journal Sentinel

Stem cell patent to benefit MCW research

Aug. 29 - Cellular Dynamics International Inc., a Madison-based biotechnology company, was granted a patent for its stem cell production automation process. Ulrich Broeckel, MD, professor of pediatrics (genetics) and an investigator at the Children’s Hospital of Wisconsin Research Institute, discussed the importance of this patent and how it will help research at MCW. Milwaukee Journal Sentinel

Dr. Medhora is Co-Founder of Personal Genomics Clinic in India

Aug. 13 - Meetha Medhora, PhD is a co-founder of Positive Bioscience, a personal genomics clinic in Gurgaon, India. Pharma Biz, Hindustan Times and The Times of India

Dr. Dimmock Discusses Impact of Genome Sequencing for Identifying Rare Diseases

Aug. 04 - Dr. David Dimmock contributes to an article in The Telegraph (United Kingdom) on the benefits of genome sequencing for families afflicted by rare genetic disorders. The Telegraph

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Page Updated 10/05/2014