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MCW Research News - Basic Sciences

$6 million grant funds National EPR Center

May 15 - The National Biomedical Electron Paramagnetic Resonance (EPR) Center at the Medical College of Wisconsin (MCW) has received a five-year, $6 million renewal grant from the National Institute of Health’s National Institute of Biomedical Imaging and Bioengineering. The EPR Center was established in 1976, and has been continuously funded since. It is classified as a Biomedical Technology Resource Center, and is one of eight federally-designated research centers at MCW.

Brain and spinal cord Injury research programs at VA

May 14 - The Medical College of Wisconsin and the Clement J. Zablocki VA Medical Center are collaborating to improve the lives of those with traumatic brain injuries and spinal cord injuries.

Sean Scherer, M1, receives AGA Student Fellowship Award for research on CVS

May 14 - Sean Scherer, a first year medical student at the Medical College of Wisconsin (MCW), has been awarded the 2013 American Gastroenterological Association’s Student Research Fellowship Award. This award provides monetary support for students in the hope of stimulating interest in careers pertaining to digestive diseases.

College to honor National VA Research Week May 13-17

May 13 - The week of May 13-17 is VA Research Week, and the Medical College of Wisconsin will be observing the event with a series of articles that highlight the research collaboration between the College and the Clement J. Zablocki VA Medical Center.

Dr. Hessner Receives NIH Grant to Develop Assay to Detect Type 1 Diabetes

May 7 - Martin J. Hessner, PhD, received a three-year, $857,000 grant from the National Institute of Diabetes and Digestive and Kidney Diseases to continue to develop an assay shown to detect inflammation linked to the development of Type 1 diabetes before patients are symptomatic. WauwatosaNOW

Researchers to study socioeconomic factors in breast cancer mortality rates

May 07 - The Medical College of Wisconsin (MCW) has received a $1.1 million, three year grant from the National Institutes of Health National Cancer Institute to study socioeconomic disparities in breast cancer outcomes.

Predicting type 1 diabetes at a molecular level

May 03 - The Medical College of Wisconsin and Children’s Hospital of Wisconsin Research Institute received a three-year, $857,000 grant from the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases to continue to develop an assay shown to detect inflammation linked to the development of Type 1 diabetes (T1D) before patients are symptomatic.

Dr. Kim Receives $1.5 Million NIH Grant to Study Enzymes involved in Fatty Acid Oxidation

May 1 - Jung-Ja Kim, PhD, received a four-year, $1.5 million grant from the National Institute of General Medical Sciences to study the structure and function of enzymes involved in fatty acid oxidation. WauwatosaNOW

Neuroscience Research Center requests proposals for pilot grants

May 03 - The Neuroscience Research Center plans to fund four categories of pilot grants to enhance research capacity in the area of neuroscience research. The largest awards will fund collaborative projects involving two or three faculty members.

Researcher to investigate enzymes involved in fatty acid oxidation

Apr 25 - The Medical College of Wisconsin received a four-year, $1.5 million award from the National Institute of General Medical Sciences, National Institutes of Health to study the structure and function of enzymes involved in fatty acid oxidation.

Dr. Hudson Receives $476,000 NIH Grant to Study Immune Response to Herpesviruses

April 16 - Amy Hudson, PhD, received a two-year, $476,000 grant from the National Institute of Allergy and Infectious Disease to study immune response to certain herpesviruses. WauwatosaNOW

Final Vision Science Distinguished Lecture planned for April 22

Apr 18 - The Department of Ophthalmology is presenting the final Vision Science Distinguished Lecture of the 2012-2013 series on Monday, April 22, from 12-1 p.m. in the lower level of the Froedtert & The Medical College of Wisconsin Eye Institute. Jeffrey L. Goldberg, MD, PhD, Professor of Ophthalmology and Director of Research at the Shiley Eye Center at the University of California – San Diego, will give a presentation titled, Retinal Ganglion Cell Survival and Regeneration.

Researcher to study evasive immune strategies of herpesviruses

Apr 15 - The Medical College of Wisconsin has received a two-year, $476,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to study immune response to certain herpesviruses.

Researcher to study mechanisms of coronary artery disease

Apr 10 - The Medical College of Wisconsin has received a four-year, $1.7 million grant from the National Institutes of Health’s National Heart, Lung and Blood Institute to study the mechanisms and agents influencing blood flow to the heart.

Primorigin Biosciences: Madison Firm Receives $1.2 Million NIH Grant; Company Partners with MCW

April 4 - The NIH awarded a $1.2 million Phase 2 Small Business Innovation Research Grant to Primorigin Biosciences in Madison. Wisconsin State Journal

M Magazine Profiles Three Cancer Researchers

April 4 - M Magazine profiles three MCW cancer research studies underway at Froedtert and Children’s Hospital of Wisconsin: Dr. Stuart Wong’s research on drug therapies for advanced stage melanoma; Dr. Monica Thakar’s research on natural killer white cells in the treatment of solid tumors; and Dr. Jill Gershan’s research on the use of T cells in the treatment of multiple myeloma. M Magazine

Dr Hudson Receives $476,000 NIH Grant to Study Immune Response to Human Herpesviruses

March 25 - Amy Hudson, PhD, (Microbiology and Molecular Genetics) received a two-year, $476,000 grant from the National Institute of Allergy and Infectious Disease to study immune response to two forms of human herpesvirus. WauwatosaNOW

Alumni/Students/Patients in Wisconsin

Wisconsin map of Alumni, Students and Patients

Teng Receives NIH Grant to Study Protection of Newborn Lungs

March 20 - Dr. Ru-Jeng Teng received a two-year, $150,000 grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development to study the use of a compound to protect the lungs of newborns against damage from exposure to excessive levels of oxygen. WauwatosaNOW

MCW Researcher to Study Evasive Immune Strategies of Herpesviruses

Mar 21 - The Medical College of Wisconsin has received a two-year, $476,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to study immune response to certain herpesviruses.

Metabolism research workshop planned for April 11

Mar 19 - The Bioenergetics Shared Resource is hosting a workshop on metabolism research on Thursday, April 11, from 9 a.m. to 4 p.m. This event is hosted by the MCW Cancer Center, and is open to researchers from MCW and other institutions.

Preventing lung injury in newborns

Mar 13 - The Medical College of Wisconsin and Children’s Hospital of Wisconsin Research Institute received a two-year, $150,000 award from the National Institutes of Health’s Eunice Kennedy Shriver National Institute of Child Health and Human Development. The award will fund an investigation into the use of a compound to protect the lungs of newborns against damage from exposure to excessive levels of oxygen.

Impact of Sequestration on MCW

March 12 - Sequestration will force $5-9 million in federal funding cuts to MCW. Milwaukee Journal Sentinel & The Badger Herald

16 CTSI Grants Awarded for 2013 Totaling $775,000

March 5 - The Clinical and Translational Science Institute of Southeast Wisconsin is funding 16 new projects in 2013 totaling $775,000. Newly-funded projects include research on cancer, cardiovascular disease, the neurosciences, diabetes, and arthritis. WauwatosaNOW

Cardiovascular, blood research on common ground

Researchers from the Medical College of Wisconsin and the BloodCenter of Wisconsin collaborate on cardiovascular research to address many pressing disorders of the blood and vascular system.

Teams study impact of environment on child health

A partnership between UW-Milwaukee, Children's Research Institute of Children's Hospital and Health System, and the Medical College is dedicated to understanding how environmental factors relate to reproductive and childhood diseases and finding ways to prevent them.

Web Extra: Interest in brain research led student to joint PhD program

In 2004, Jeannette Vizuete began in the PhD program in Functional Imaging jointly offered by the Medical College of Wisconsin and Marquette University. Jeannette is now nearing completion of the program and the achievement of her PhD. In this Q and A, Jeannette talks about her research and the program.

Web Extra: National and Global Collaborations

Medical College faculty and staff have collaborations on six continents and nearly all states in the nation. For details on specific collaborations, see the following information, which is conservative summary of the continuously expanding collaborations in all missions of the Medical College.

PhD program joins bioscience and engineering

The Medical College of Wisconsin and Marquette University jointly offer a PhD program in Functional Imaging, which integrates experience in biomedical science and applied engineering in studies related to the brain.

Biomedical sciences student learns by doing

MD-PhD student Max Cayo has accomplished the rare feat of obtaining an NIH grant as a student, and with his mentor, Stephen Duncan, PhD, is advancing research to improve treatments for cardiovascular diseases.

Drs. Robinson and McNally Receive NIH Grant to Study Tuberculosis Immunity

Feb. 19 - Richard T. Robinson, PhD, and Mark McNally, PhD, received a two-year, $420,000 NIH grant to study tuberculosis immunity. WauwatosaNOW

MCW researchers to study tuberculosis immunity

Feb 12 - The Medical College of Wisconsin has received a two year, $420,000 grant from the National Institutes of Health to study proteins associated with tuberculosis immunity.

MCW Researcher studies promising treatment for rare muscle disease

Jan. 25 - A collaborative team of researchers led by Michael Lawlor, MD, PhD, assistant professor of pathology, found promising results for a treatment of a rare, severe muscle disease. Milwaukee Journal Sentinel

Enzyme replacement therapy shows promising results in X-Linked myotubular myopathy

Jan 22 - A collaborative research team including a Medical College of Wisconsin pediatric neuropathologist successfully mitigated some of the effects of a muscular disease by using a new targeted enzyme replacement therapy strategy from 4s3 Bioscience.

College’s NIH funding rank among medical schools highest in more than a decade

Jan. 11 - The Medical College of Wisconsin was ranked 42nd among the nation’s 136 medical schools receiving National Institutes of Health (NIH) research and training support in FY 12 (2011-12). This is the highest rank the Medical College of Wisconsin has received in more than ten years.

NIH Grant to for Diabetes Gene Research Identified as One of Wisconsin’s Top Brainstorms

Jan. 7 - The Milwaukee Journal Sentinel identifies a $4.3 million NIH grant awarded to MCW as one of 15 Wisconsin brainstorms for 2012. Milwaukee Journal Sentinel

Researcher to study non-alcohol fatty liver disease

Dec. 10 - Nita H. Salzman, MD, PhD, a pediatric gastroenterology researcher at the Medical College of Wisconsin (MCW) and Children’s Hospital of Wisconsin, received a five-year, $7 million grant from the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases. The award will fund an investigation into the link between intestinal bacteria and non-alcoholic fatty liver disease (NAFLD).

Students seasoned for science

A record number of students participated this year in the Medical College’s Medical Student Summer Research Program, which pairs first- and second-year students with a faculty mentor for a laboratory-based research experience. The program gives future doctors perspective on how new discoveries are translated into the tools and treatments of tomorrow.

Medical College of Wisconsin researchers to investigate spinal disc degeneration

Nov., 07 - A research team at the Medical College of Wisconsin received a three-year, nearly $400,000 AOSpine Research Network award from AOSpine International of Davos, Switzerland, to study imaging methods of spinal disc degeneration.

Celebrating Brad Chili Cook-off on Dec. 8 to benefit MCW cancer research

Nov. 05 - The Celebrating Brad Foundation is holding a chili cook-off on Saturday, Dec. 8, from 5-10 p.m. at Flux Design, 811 E. Vienna in Milwaukee. Proceeds from the event will support cancer research at the Medical College of Wisconsin.

Scientists explore novel ways to mitigate neuroinflammation in Parkinson’s disease model

Nov., 01 - Balaraman Kalyanaraman, PhD, Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research and Chairman of Biophysics, and his research team were co-authors on a study, Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson’s disease, published in the online version of the Journal of Neuroinflammation.

Crash Tests Performed by MCW Researchers Help Determine Car Safety Ratings

Some vehicle safety ratings are based on information gathered at the Medical College of Wisconsin and provided to the National Highway Traffic Safety Administration. FOX 6 News

MCW and Children’s Hospital of Wisconsin to study genetics of Type 1 diabetes

Oct. 26 - The Medical College of Wisconsin (MCW) and Children’s Hospital of Wisconsin Research Institute received a four-year, $4.3 million grant from the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases to investigate the genes involved in type 1 diabetes (T1D).

MCW receives $10,000 for foundation researching therapies for rare abdominal cancer

October 16 - Hundreds of people participated in a 5K run on September 29th to raise money for the Sebastian Raclaw Abdominal Cancer Research Fund, named for the Milwaukee police officer battling Pseudomyxoma Peritonei. FOX 6 News

MCW researcher receives grant to investigate autoantibody production in autoimmune disorders

Stephen Gauld, PhD, MCW assistant professor of pediatrics in allergy and immunology, and microbiology and molecular genetics, will study the factors involved in regulating the production of autoantibodies, which target an individual’s own tissues and are linked to autoimmune disorders like lupus and rheumatoid arthritis. Health News Digest

MCW, Children’s Hospital of Wisconsin to investigate autoantibody production in autoimmune disorders

Oct. 09 - The Medical College of Wisconsin and Children’s Hospital of Wisconsin Research Institute received a one-year award for more than $375,000 from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases. The award will fund an investigation of the factors involved in regulating the production of autoantibodies, which are antibodies that target an individual’s own tissues. These autoantibodies are linked to autoimmune disorders like lupus and rheumatoid arthritis.

Milwaukee Police Sergeant Battling Rare Abdominal Cancer Raising Money to Support Research at MCW

More than 500 people participated in a 5K run to show support for Officer Sebastian Rawclaw and raise money for research and treatment. FOX6 News

MCW Receives $75,000 from the Greater Milwaukee Foundation for Cardiovascular Disease Research

One project will investigate how inflammatory cells are linked to heart failure in patients with high blood pressure. Two other studies will look at predicting heart failure and reversing damage. Milwaukee Business Journal

Researcher to investigate tuberculosis bacterium

Sept. 24 - The Medical College of Wisconsin (MCW) received a two-year award for more than $400,000 from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to study how the bacterium which causes tuberculosis (TB) survives inside the human body in a latent state which is less susceptible to antibiotics

MCW Researcher Creates Career Planning Tool for Scientists

Philip S. Clifford, PhD, associate dean for postdoctoral education in the Graduate School of Biomedical Sciences and professor of anesthesiology and physiology at MCW, creates an interactive career planning tool to help budding scientists develop step-by-step plans to reach their goals. Science Careers

Medical College of Wisconsin Receives Grant to Study Heart Failure

Jennifer Strande, MD, PhD, assistant professor of cardiovascular medicine and Shama Mirza, PhD, assistant professor of biochemistry, received a $50,000 grant from the Clinical and Translational Science Institute of Southeast Wisconsin to study a specific type of heart failure and to identify biomarkers that might allow clinicians to diagnose and treat earlier. Milwaukee Business Journal

MCW Research Finds Lack of Sleep Affects Bone Health and Bone Marrow Activity

Lead researcher Carol Everson, PhD, professor of neurology, cell biology, neurobiology and anatomy, says chronic sleep restriction leads to an arrest in bone remodeling that could potentially affect healing. Science Daily

Researcher to study Lou Gehrig’s Disease

Sept 14 - The Medical College of Wisconsin has received a $40,000 grant from the ALS Association’s Jeff Kaufman Fund to study the impact of skeletal muscle on the progression of ALS, or Lou Gehrig’s Disease, as it’s commonly known.

Medical College of Wisconsin researcher to study ear infections

Sept. 05 -The Medical College of Wisconsin and Children’s Hospital of Wisconsin Research Institute received a five-year, $1.6 million grant from the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders. The study will investigate ear infections and explore potential new treatments.

Medical College of Wisconsin Receives Grant to Study Ear Infections

Joseph Kerschner, MD, executive vice president and dean of the medical school, received a $1.6 million grant from the NIH to target new potential treatments for ear infections in children. BizTimes

Medical College researchers to study intestinal bacteria

Aug. 14 - The Medical College of Wisconsin received a two-year, $420,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to investigate the interactions between bacteria that live in the intestine and the intestinal immune system.

Medical College researcher to study target for treating depression

Aug. 02 - The Medical College of Wisconsin received a two-year, $420,000 grant from the National Institutes of Health’s National Institute of Mental Health to study the viability of a promising target for the pharmacological treatment of depression.

Medical College of Wisconsin researcher to study new treatment for chronic pain

July 26 - The Medical College of Wisconsin received a four-year, $1.1 million grant from the National Institutes of Health’s National Institute of Neurological Disorders and Stroke to study the use of genetically modified adult stem cells to treat neuropathic pain.

Cardiology fellow Dr. Sharath Subramanian is first author on new JAMA article

July 25 - Sharath Subramanian, MD, cardiology fellow at the Medical College of Wisconsin, is first author on a paper published in the July 25 online issue of "JAMA, the Journal of the American Medical Association." The paper, "Arterial Inflammation in Patients with HIV," investigated the role of arterial inflammation leading to increased cardiovascular disease in patients with human immunodeficiency virus (HIV).

Congratulations to the Class of 2012

The 99th annual commencement took place on May 18 at the Milwaukee Theatre, at which the Medical College of Wisconsin and its Graduate School of Biomedical Sciences awarded 202 MD, 38 PhD, 27 MS, 4 MA, and 18 Master of Public Health degrees, as well as bestowed numerous honors.

Medical College researcher to study protein linked to diabetes and liver disease

July 16 - The Medical College of Wisconsin received a four-year, $1.3 million grant from the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases to fund an investigation of a key regulatory protein linked to diabetes and liver disease.

Photochemically generated selenium kills leukemia and solid tumor cells

July 05 - Researchers at the Medical College of Wisconsin (MCW) and the Children's Research Institute in Milwaukee have found that extremely small particles of elemental selenium are highly toxic to leukemia and certain solid tumor cells but well tolerated by normal cells. The small particles are generated when certain selenium-containing dyes are exposed to light, and this small size appears to be essential for the anti-cancer effect.

Medical College researcher to study potential treatment for botulism

July 02 - The Medical College of Wisconsin (MCW) received a two-year, $420,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to investigate a promising biological avenue for treating nerves affected by botulism.

Medical College researcher to study new pathway for psoriasis

June 20 - The Medical College of Wisconsin received a two-year, $200,000 grant from the National Psoriasis Foundation to study the pathogenesis of psoriasis and to identify new drugs that may benefit patients.

Scientists Update Study on Microbes Within Us

John Baker, PhD, Professor of Cardiothoracic Surgery, Biochemistry, Pharmacology and Chemistry, discusses the Human Microbiome Project and its importance in both current and future health research. Milwaukee Journal Sentinel

Radiation Exposure Could Show up in our Genetic Script

John Baker, PhD, professor of surgery and biochemistry, found a link between radiation exposure and increases in certain type of bacteria in the body. Milwaukee Journal Sentinel

Novel biomarkers reveal evidence of radiation exposure

May 23 - Researchers at the Medical College of Wisconsin have identified novel biomarkers that could be used to confirm exposure to damaging radiation in large groups of people potentially exposed to unknown and variable doses for the purpose of triage and treatment.

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Page Updated 01/24/2013