Research

Scanning Information

Before working with the MEG, researchers are required to gain approval from the MCW Institutional Review Board (IRB) and Froedtert Hospital’s Office of Clinical Research and Innovative Care Compliance (OCRICC). This means that no researcher will be allowed to work with any hardware, software, or devices in the MEG suite before they have been approved by both the IRB and OCRICC.

IRB Approval

  • MCW Researchers: All MCW researchers must be approved by the MCW IRB. This can be done by creating an IRB proposal in eBridge.
  • Non-MCW Researchers: All non-MCW researchers must have approval from their own institution’s IRB or comparable committee. Once approved, researchers must register with the MCW IRB to obtain an IRB project number.

OCRICC Approval

  • All researchers who wish to use the MEG scanner must have OCRICC approval. It is recommended that OCRICC approval be applied for at the same time as IRB approval. Approval can be requested by filling out the online forms, “OCRICC Project Application Form” and “PHI Checklist” at the OCRICC website. Please ask the MEG scheduler (rrohloff@mcw.edu) for the forms if you cannot download them, then email them directly to the OCRICC at ocricc@froedterthealth.org.

MEG Committee

  • All researchers must also gain approval from the MEG Committee before they may begin research. To be approved by the MEG Committee, researchers must email their proposal to Dr. Colin Humphries. chumphries@mcw.edu

Scheduling

To schedule a scan time with the MEG scanner you must have received approval from both the IRB at MCW and the OCRICC at Froedtert Hospital. Once you have approval you may email the MEG scheduler at rrohloff@mcw.edu. All researchers must schedule training/development (non-scanning) and testing times before they will be allowed to scan a subject in the MEG. Research scans may be scheduled for any week day after 1:00pm. The MEG will not be available Tuesday afternoons as the scanner undergoes weekly maintenance at that time. If absolutely necessary, weekend scans may be requested. Please email the MEG scheduler at rrohloff@mcw.edu.

 

Funding Opportunity

MEG Pilot Research Grants 2015

The MEG Research and Development Program at MCW, an initiative funded by the Advancing a Healthier Wisconsin (AHW) Research and Education Program (REP), is requesting applications for pilot research projects using magnetoencephalography (MEG) technology. As part of this initiative, the MEG Research Development Program will fund pilot projects utilizing MEG as a primary source of data. Details can be found from here:  Request For Applications.

 

Important Dates
RFA Release Date: March 2, 2015

Grants and Contracts Deadline:  April 3, 2015

Application Deadline:  April 10, 2015

Funding Start Date: August 3, 2015

 

Contacts: 

(1)   Robert S. Rohloff, Clinical Research Assistant, Department of Neurology, Medical College of Wisconsin, rrohloff@mcw.edu 414-955-4614

(2)   Colin Humphries, PhD, Assistant Professor, Department of Neurology, Medical College of Wisconsin, chumphri@mcw.edu, 414-955- 4660

 

Current Research Projects

Our core research activities focus on developing new methods, analysis techniques and software to promote MEG/EEG as a genuine functional brain imaging modality. The unique, superlative time resolution of MEG makes it a challenging endeavor, because of the high-density and multi-dimensional aspects of the data (3D space, time, frequencies, connectivity bonds between brain areas, etc.). This page briefly summarizes our methodological research and the clinical research projects we are developing with collaborators on and beyond the campus and the hospital partners.

Functional image reconstruction from MEG/EEG data with coregistration with MRI

Inverse image estimation, modeling, statistical appraisal.

MNE


Detection and characterization of neuromodulatory effects of Cortical and Deep Brain Stimulation (CS, DBS)

  • Movement disorders, Depression, Chronic pain, Tinnitus

direct causality

Functional imaging biomarkers of epilepsy

Investigating the brain's ongoing rhythms to reveal the origins and the characteristics of epileptic dysfunctions.

  • Collaboration with M. Raghavan (Neurology) and W. Mueller (Neurosurgery).

spiking recurrence

 

Anatomical and electrophysiological imaging models of deeper brain structures

  • Basal ganglia, hippocampus

deeper brain structures

 

Software Usage/developments

  • We use BrainStorm and other software
  • In-house development of MEG-Clinic
    • A comprehensive software solution for routine MEG analysis.

Froedtert & The Medical College of Wisconsin MEG Contact Information

Research investigators and clinical physicians are encouraged to contact us for further information on how to access our MEG Program and services.

  • Zhimin Li, PhD: Technical Manager
  • Jean Roccapalumba, CTRS, MBA: Program Manager

Mailing Address:

MEG Program
Department of Neurology
Medical College of Wisconsin
9200 W. Wisconsin Ave.
Milwaukee, WI 53226

MEG Program Site Map


If you are a physician and would like to inquire about or order a MEG study for your patients, please visit Froedtert Hospital MEG web pages for basic information about the procedure and/or contact Linda Allen, RN BSN, our Epilepsy Program Coordinator at (414) 805-3641 to refer your patient to our Program.

If you are a patient who is about to undergo an MEG procedure, please also visit Froedtert Hospital MEG web pages for useful information regarding the MEG routine.

Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226
(414) 955-8296
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© 2015

Page Updated 03/05/2015
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