Natural History Study of the Development of Type 1 Diabetes
Type 1 Diabetes TrialNet is a global network of researchers and immunology experts dedicated to the study, prevention, and early treatment of type 1 diabetes. It is supported by the Department of Health and Human Services National Institutes of Health, Juvenile Diabetes Research Foundation International, and the American Diabetes Association.
The Max McGee National Research Center for Juvenile Diabetes* is an Affiliate Site for the Natural History Study of the Development of Type 1 Diabetes. This study screens relatives of people with type 1 diabetes to find out if family members are at risk for developing diabetes.
The purpose of this study is to gain more information about how type 1 diabetes develops. Then studies can be designed for people who are at risk for developing type 1 diabetes or have just been told they have type 1 diabetes. The more information scientists have, the better they can design studies to find possible treatment and prevention options for type 1 diabetes. But first, the Natural History Study may help find more information about the disease.
TrialNet also has prevention studies and intervention studies. If you are enrolled in the Natural History Study and learn you are at risk for developing type 1 diabetes, you may qualify to be enrolled in a prevention study. If you develop diabetes during the study, you may qualify for an intervention study.
You may be able to take part in this study if you are:
Between 1 and 45 years old and have a brother, sister, child or parent who has been diagnosed with type 1 diabetes
Between 1 and 20 years old and have a cousin, niece, nephew, aunt, uncle, half sibling, or grandparent who has been diagnosed with type 1 diabetes
You may not be able to participate if you:
have diabetes already
have a previous history of being treated with insulin or oral diabetes medications
are currently using systemic immunosuppressive agents (topical or inhaled agents are acceptable
have any known serious diseases
You may contact the study coordinator for more information:
Trialnet Study Coordinator
Max McGee National Research Center for Juvenile Diabetes
Children’s Hospital of Wisconsin/ Medical College of WI
8701 Watertown Plank Road
Milwaukee, WI 53226
Type 1 Diabetes Research Studies at TrialNet Brochure (Adobe PDF)
A visit to Children’s Hospital of WI to donate a blood sample which will be screened for diabetes-related antibodies
Answering a few medical history questions
Possible follow-up: individuals with a positive antibody result may be offered further testing to determine their risk of developing diabetes over the next 5 years. You would need to give additional permission to participate in the next stage of testing.
National Institute of Diabetes & Digestive & Kidney Disease (NIDDK)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Child Health and Human Development (NICHD)
National Center for Research Resources (NCRR)
Juvenile Diabetes Research Foundation International (JDRF)
American Diabetes Association (ADA)
*The Max McGee National Research Center for Juvenile Diabetes is affiliated with the Medical College of Wisconsin and Children’s Hospital of Wisconsin.