Anthony PriscoAnthony Prisco

aprisco@mcw.edu

Research Interests

Regenerative Medicine (Angiogenesis, Stem Cells)
Ventricular Assist Device Design (Computational Fluid Dynamics)
Bioengineering (Quantum Mechanics, Monte Carlo Simulations, Artificial Intelligence) Signal Processing (Image Processing and Object Tracking)

Advisor: Andrew Greene, PhD, Department of Physiology

Current Appointments

OSR Representative, Class of 2012

Education

BS, 2008, Marquette University
Major: Biomedical Engineering

PhD, 2014, Medical College of Wisconsin
Thesis: The Engraftment Problem: TNFα Increases Adhesion and Migration of Endothelial Progenitor Cells to Vascular Endothelial Cells

Research Experience

Baxter Healthcare Corporation, 2007
Advisor: Hsinjin Yang, PhD
Project: Study of Peel Seal via Argon Plasma Treatment

Medical College of Wisconsin, 2005-2006
Advisor: Brian Shames, MD
Project: The Role of 20-HETE in Ischemic Acute Renal Failure

Bibliography

Manuscripts
Prisco, A. R., Bukowy, J. D., Hoffmann, B. R., Karcher, J. R., Exner, E. C., & Greene, A. S. (2014). Automated Quantification Reveals Hyperglycemia Inhibits Endothelial Angiogenic Function. PLOS ONE, 9(4), e94599.

Prisco, S. Z., Priestley, J. R., Weinberg, B. D., Prisco, A. R., Hoffman, M. J., Jacob, H. J., ... & Lazar, J. (2014). Vascular dysfunction precedes hypertension associated with a blood pressure locus on rat chromosome 12. American Journal of Physiology-Heart and Circulatory Physiology, 307(8), H1103-H1110.

Greene, A. S., Parker, S. J., Prisco, A. R., (2015). Broken Bones/Broken Heart: The Cardiovascular-Bone Marrow Axis. Shinzo, 47, 248-250

Prisco, A. R., Prisco, M. R., Carlson, B. E., & Greene, A. S. (2015). TNFα Increases Endothelial Progenitor Cell Adhesion to the Endothelium by Increasing Bond Expression and Affinity. American Journal of Physiology-Heart and Circulatory Physiology, 308, H1368-H1381.

Hoffmann, B. R., J. R. Wagner, A. R. Prisco, A. Janiak, and A. S. Greene, Vascular endothelial growth factor-A signaling in bone marrow-derived endothelial progenitor cells exposed to hypoxic stress. Physiol Genomics, 2013. 45(21): p. 1021-34.

Kaczorowski, C. C., T. J. Stodola, B. R. Hoffmann, A. R. Prisco, P. Y. Liu, D. N. Didier, J. R. Karcher, M. Liang, H. J. Jacob, and A. S. Greene, Targeting the endothelial progenitor cell surface proteome to identify novel mechanisms that mediate angiogenic efficacy in a rodent model of vascular disease. Physiol Genomics, 2013. 45(21): p. 999-1011.

Abstracts
Shames, B. D., Layman, R., Hilton, G., Prisco, A. R., Johnson, C. P., Pieper, G. M., & Nilakantan, V. (2006). Inherent resistance to acute ischemic renal injury in the Brown Norway rat is mediated by heme oxygenase-1. Journal of Surgical Research, 130(2), 207.

Prisco, A. R., Olson, L. Greene, A. S. “A Novel Way of Measuring Cell Interaction Strength.” FASEB J. March 17, 2011 25:820.12

Prisco, A. R., and A. S. Greene, Measurement of the Binding Strength of Endothelial Progenitor Cells to Vascular Endothelial Cells in Shear. The FASEB Journal, 2012. 26: p. 1129.7.

Hoffmann, B. R., J. R. Wagner, A. R. Prisco, and A. S. Greene, Vascular Endothelial Growth Factor-A signaling in Bone Marrow-Derived Endothelial Progenitor Cells Exposed to Hypoxia. The FASEB Journal, 2013. 27: p. 685.7.

Prisco, A. R., B. R. Hoffmann, C. C. Kaczorowski, and A. S. Greene, Targeted Proteomics: Endothelial Cell Membrane Response to TNF-α. The FASEB Journal, 2013. 27: p. 737.6.

Prisco, A. R., B. R. Hoffmann, C. C. Kaczorowski, and A. S. Greene, The Engraftment Problem: Identifying Proteins that Mediate Stem Cell Adhesion. The FASEB Journal, 2013. 27: p. 874.2.

Kaczorowski, C. C., T. J. Stodola, B. R. Hoffmann, A. R. Prisco, P. Lui, D. Didier, J. Karcher, M. Liang, H. Jacob, and A. S. Greene, Abstract 48: Targeting the Endothelial Progenitor Cell Surface Proteome to Identify Novel Mechanisms that Mediate Angiogenic Efficacy and Restore Angiogenesis in a Rodent Model of Vascular Disease. Hypertension, 2013. 62: p. A48.

Prisco, A. R., B. R. Hoffmann, J. D. Bukowy, J.R. Karcher, and A. S. Greene, Abstract 232: High Glucose Attenuates In Vitro Tube Growth of Microvascular Endothelial Cells. Hypertension, 2013. 62: p. A232.

Hoffmann, B. R., A. R. Prisco, J. Wang, T. M. Suboc, M. E. Widlansky, and A. S. Greene, Abstract 230: Evaluation of Hyperglycemia-Driven Alterations on Vascular Endothelial Function. Hypertension, 2013. 62: p. A230.

Hoffmann, B. R., A. R. Prisco, and A. S. Greene, Hyperglycemia-driven glycosylation of the AT1 receptor in the vascular endothelium (1086.8). The FASEB Journal, 2014. 28.

Prisco, A. R., B. R. Hoffmann, C. C. Kaczorowski, and A. S. Greene, TNFα regulates endothelial progenitor cell migration through the NF-κB pathway (1180.16). The FASEB Journal, 2014. 28.

Hoffmann, B. R., Prisco, A. R., Widlansky, M. E., & Greene, A. S. "Hyperglycemia-induced alterations of the vascular endothelium in type 2 diabetes mellitus." The FASEB Journal 29, 2015: 802-4.

McGah, P., Prisco, A. R., Garcia, G., Beckman, J. A., Mokadam, N. A., Mahr, C., Aliseda, A. “Computational Optimization of LVAD Outflow Graft Configuration.” ASAIO Journal 2015, 153: p. 64. 

Prisco, A. R., McGah, P., Garcia, G., Beckman, J. A., Mokadam, N. A., Aliseda, A., Mahr, C. “Influence of LVAD Inflow Cannula Placement Location on the Flow Stresses and Residence Time in the Left Ventricle.” ASAIO Journal 2015, 155: p. 65.  *Selected for oral presentation
 

Posters
Prisco, A. R. Humphrey, S. Schuckit, S. “Student-Guided Curriculum Design at the Medical College of Wisconsin.” Poster session presented at the 2009 AAMC National Conference.  2009, November 6-12; Boston, MA

Prisco, A. R. Ford, C. Humphrey, S. Simpson, DS. “Recipe for Success: What Influences Student Success in Academic Projects?” Poster session presented at the 2010 AAMC National Conference. 2010, November 5-11; Washington DC

Prisco, A. R. Prisco, M. R. Greene, A. S. “Fluid Dynamic Analysis of a Custom In-Vitro Flow Chamber.” Poster session presented at the 2011 BBC Innovation Day. 2011, February 10; Milwaukee, WI

Sheets, LM. Prisco, A. R. Ford, C. Simpson, DS. “Pathways to Public Health: Integrating Public Health into the Medical School Curriculum.” Poster session presented at the 2011 AAMC National Conference. 2011, Nov 4-11; Denver, CO

Mantha, A. Ray A. Prisco A. R. Bagwell, S. Deci, D. Schapiro, R. “Use of a Poverty Simulation in Medical Education.” Poster Presented at the 2012 AAMC Regional Conference, 2012, March 29-April 1; Clearwater Beach, FL

Priestley, J. R. C., Weinberg, B. D., Prisco, A. R., Endres, B., Casati, M., Geurts, A. M., Lombard, J. H., “Nrf2 Mutation Eliminates Vasoprotective Effects of Low Dose Angiotensin II Infusion in Sprague-Dawley Rats Fed High Salt Diet.” Poster Presented at the 2014 Experimental Biology Conference, 2014, April 26-April 30; San Diego, CA

Invited External Presentations
“Use of a Poverty Simulation in Medical Education.” Presented at the 2012 AAMC Regional Conference, March 30, 2012; Clearwater Beach, FL

“Heart Failure: New Treatments, Engineering, and Patients – Can a Single Person Integrate These?” Invited Lecturer for the Intro to Biomedical Engineering Class, Marquette University, April 22, 2014

“TNFα Regulates Endothelial Progenitor Cell Migration via CADM1 through the NF-kB Pathway.” Invited Speaker for the Department of Biomedical Engineering Seminar Series, Marquette University, May 9, 2014

Awards

2013 American Heart Association Scientific Sessions: Poster Competition Winner, New Orleans, LA
2011-2013 Medical College of Wisconsin: Travel Award Winner

Volunteering

Medical College of Wisconsin:
Biotechnology and Bioengineering Center (BBC) Educational Outreach Program, 2012 - Present
Engineering Mentor, Future Cities Competition (Students at Holy Apostles Middle School)
Science Mentor, Middle School Science Fair (Students at St. Matthias School)
Lecturer, Bioengineering for High School Teachers (BBC Summer Teacher Institute)
Workshop Leader, Proteomics Made Easy - Legos! (Waukesha Middle Schools Bioengineering Days at MCW BBC)

Leadership/Professional Activities

2015 - present, Reviewer, International Journal of Dermatology and Clinical Research
2014 - present, Reviewer, Journal of Stem Cell Research and Regenerative Medicine
2014 - present, Reviewer, Journal of Heart and Lung Transplantation
2009 - 2012, Medical College of Wisconsin, Class of 2012 AAMC OSR Representative
2009 - 2010, Medical College of Wisconsin, Student Assembly, Alumni Relations Committee Member
2009 - 2010, Medical College of Wisconsin, Student Assembly, Awards Committee Member
2008 - 2012, Medical College of Wisconsin, MSTP, Retreat Committee Member

Interests

cycling, woodworking, tinkering with cars/electronics in the garage

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Page Updated 08/28/2015
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