Functional and physical interactions of small GTPases with SmgGDS in the hopes of better understanding the cell signaling pathways leading to cancer.
Advisor: Carol Williams, PhD, Department of Pharmacology & Toxicology
BA, 2010, Washington University in St. Louis
Washington University in St. Louis, 2007-2010
Advisor: Dr. Carolyn Anderson
Project: PET Imaging of the Pre-Metastatic Niche with 64Cu-CB-TE2A-LLP2A, a High Affinity Ligand for Integrin α4β1, High Throughput Assays for Screening alpha-v beta-3-Targeted Nanoparticles, 64Cu-RGD and microPET/CT as an Imaging Biomarker for Osteoclast Number in Mouse Models of Negative and Positive Osteoclast Regulation
Schuld, NJ., Hauser, AD., Gastonguay, AJ., Wilson, JM, Lorimer, EL., and Williams, CL. SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers. Cell Cycle. 2014 Mar 15.
Zimmerman NP*, Roy I*, Hauser AD, Wilson JM, Williams CL, Dwinell MB. Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells. Mol Carcinog. 2013 Sep 24. (Epub Ahead of Print)
Monica Shokeen, Alexander Zheleznyak, Jessica M. Wilson, Kim Nguyen, Ruiwu Liu, Lynne Collins, Riccardo Ferdani, David Piwnica-Worms, Kit S. Lam, Carolyn Anderson, “PET Imaging of the Pre-Metastatic Niche with 64Cu-CB-TE2A-LLP2A, a High Affinity Ligand for Integrin α4β1.” Abstract. World Molecular Imaging Conference Journal, 2009 and Molecular Imaging and Biology Journal, 2009.
Jessica M. Wilson. “Regulation of Small GTPase Membrane Localization and Prenylation Through G-Protein Coupled Receptor Activation.” Oral Presentation and Poster Presentation. 29th Annual National MD/PhD Conference. July 20, 2014.
Jessica M. Wilson*, Andrew D. Hauser*, Carmen Bergom, Nathan J. Schuld, Xiuxu Chen, Ellen L. Lorimer, Jian Huang, A. Craig Mackinnon, and Carol L. Williams."SmgGDS-558 Promotes Breast Cancer Malignancy through Activation of RhoA." FASEB SRC Protein Lipidation, Signaling and Membrane Domains. Poster Presentation. July 17, 2013.
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