Perform intravital multiphoton imaging for neuroscience studies. The project will use in vivo multiphoton imaging and activity-dependent reporters to investigate neural ensembles engaged by drug and non-drug motivated behavior.
The successful candidate will have published proficiency in intravital imaging and motivation to develop techniques to image superficial and subcortical structures. Candidates should have strong communication skills, a record of scientific productivity, and a desire to work both independently and as part of a team.
The Neuroscience Research Center is home to over 100 neuroscientists and the Medical College of Wisconsin has numerous core facilities and other resources to promote scientific training and multidisciplinary research.
Develop and conduct experiments to study neural ensembles in mesocorticolimbic circuitry engaged by self-administration of drugs of abuse and/or non-drug rewards. Develop protocols to enable long-term studies involving repeated in vivo multiphoton imaging.
Perform experiments under the direction of the Principle Investigator, including other studies involving drug and non-drug motivated behaviors.
Develop and conduct laboratory procedures including timely data analysis and archiving of data obtained in one or more areas of laboratory investigation.
Adapt to general laboratory procedures to accomplish specific experimental goals of the laboratory, working closely in team setting with other members of the lab team.
Participate in meetings with PI and other laboratory personnel to discuss and evaluate research being undertaken and in progress.
Perform surgical procedures and behavioral experiments.
Perform other duties as assigned. Some experiments may require work on the weekends, although this is not routine.
Qualifications | Minimum Position Qualifications
Required background: PhD in Neuroscience, Cell Biology, Engineering or other relevant field. Experience with intravital imaging.
A postdoctoral position is available for an enthusiastic, hard-working individual to develop innovative research programs in the area of synaptic plasticity. The successful candidate will carry out pharmacological and structural-functional studies on recombinant receptors expressed in organotypic hippocampal cultures or in vivo. The laboratory has a strong multidisciplinary vocation. State-of-the-art electrophysiology and imaging technologies will be combined with molecular biology approaches in order to understand how individual molecules contribute to neuronal function.
Applicants should have a good background on molecular biology and/or electrophysiology. Experience in cellular biology techniques and animal handling are also desirable, but extensive training will be provided.
Send or fax your CV and references to Nashaat Gerges, PhD at the address or FAX below.
Medical College of Wisconsin
Department of Cell Biology, Neurobiology & Anatomy
8701 Watertown Plank Road
Milwaukee, WI 53226-0509
Fax: (414) 955-6517
The Stucky laboratory is looking for a postdoctoral fellow with significant molecular biology experience. Valued skills include knowledge and experience with qPCR, microarrays, RNAseq, cloning, and transgenic animal generation. In turn, the postdoctoral fellow will have an opportunity to become an expert in electrophysiology by learning teased fiber recordings, patch clamp recordings, as well as calcium imaging techniques.
Ongoing projects in the lab include mechanisms underlying mechanotransduction in sensory neurons and keratinocytes, inflammatory hypersensitivity, sickle cell disease pain, Crohn’s disease pain and mechanisms of pain in aging. Projects utilize a variety of resources to probe mechanisms of somatosensation, such as conditional transgenic lines, retrograde tracing and optogenetics.
Qualified applicants should have a recently obtained PhD or MD/PhD in neuroscience, molecular biology, immunology, cell biology or physiology. US Citizenship or Permanent Residency is required. Interest in writing independent grant applications and prior writing experience is favorable.
Please contact Dr. Stucky and include your CV and brief description of your research experience, interests and goals:
Cheryl L. Stucky, PhD
Cell Biology, Neurobiology and Anatomy
Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226
(414) 955-8373 | Fax: (414) 955-6517
The Department of Plastic Surgery at the Medical College of Wisconsin is seeking a highly motivated individual to fill a postdoctoral position in functional magnetic resonance imaging (fMRI) and biomechanical engineering. This individual is expected to develop hardware and software for a project comparing biomechanical metrics of motor-task performance with functional brain response as measured by fMRI in both healthy individuals and subjects with peripheral nerve injuries of the hand. Motor-task performance will be measured using a commercially available fiber-optic sensor glove system. The position will be based out of the Medical College of Wisconsin’s Center for Imaging Research.
The Center for Imaging Research has state-of-the-art imaging facilities, including two research-dedicated GE 3 T whole-body scanners, a Bruker 9.4 T/30 cm small-animal MRI scanner, an MEG scanner, and a microSPECT/CT. A whole-body GE 7 T human MRI scanner will be delivered early next year.
This position requires an MD or a doctoral degree in an appropriate field of biomedical engineering, mechanical engineering, biophysics, medical physics, neuroscience, computer science, or a related science field. The ideal candidate should have a strong background in MR neuroimaging techniques and methodologies, proficiency in MATLAB, and excellent written and oral communication skills. Experience with MATLAB programs Simulink, Stateflow, and xPC Target is preferred but not required. Knowledge of the biomechanics of the hand and fMRI data analysis software (AFNI, FSL, Freesurfer, etc.) is also highly desirable.
Interested candidates should submit their CV, a cover letter describing relevant qualifications and research interests, and contact information for three (3) references to Christopher Pawela, PhD, at firstname.lastname@example.org.