Pediatrics: Developmental Biology

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Developmental Biology Graduate Students

Brett Deml, a graduate student in Dr. Semina’s laboratory, joined the PhD program in Basic and Translational Sciences and IDP after four years of working in a clinical genetics lab. He is also enrolled in the PHD Program in Basic and Translational Science. His project focuses on anophthalmia, microphthalmia and ocular coloboma, using whole exome sequencing to identify novel factors involved in these disorders. A number of genes have been shown to be involved in these disorders but a large proportion of cases remain unexplained.

Kathryn Hendee, a graduate student in Dr. Semina's laboratory, is also a part of the PhD program in Basic and Translational Sciences and IDP. Her project focuses on study of the PITX transcription factor family and identification of novel genetic factors involved in anterior segement dysgenesis conditions. Her scientific passion is being in the lab performing experiments and making discoveries and she values the opportunity to see her work have a direct influence on improving the lives of patients.

Kevin Wright, a graduate student in Dr. Shim’s laboratory, is enrolled in the IDP. His scholastic interests are in developmental biology and genetics, and he is currently working to understand the molecular signals that control specification of inner ear cells. His aim in the Shim lab is to use both mouse genetics and an in vitro embryonic stem cell model to get a more precise understanding of the functions of multiple signals that induce inner ear cells. The long-term goal of these studies is to inform efforts to better differentiate inner ear cells in culture for use in the treatment of hearing deficits.

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Page Updated 12/02/2014