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Jeffrey Medin, PhDJeffrey A. Medin, PhD, named MACC Fund Endowed Professor

We are very pleased to announce the appointment of Jeffrey A. Medin, PhD, as the MACC Fund Professor in the Department of Pediatrics at the Medical College of Wisconsin (MCW). Dr. Medin has a distinguished record of accomplishment in the field of pediatric cancers, and our research and clinical partners at the MACC Fund and Children’s Hospital of Wisconsin (Children’s) joined us as active participants in this crucial recruitment.

Dr. Medin’s appointment as the MACC Fund Professor represents the importance of fighting cancer as a strategic priority of MCW, and highlights how we work closely with our partners at the MACC Fund and Children’s to improve outcomes for children and families during some of the toughest moments of their lives. Founded in 1976 by former Milwaukee Buck Jon McGlocklin and Bucks announcer Eddie Doucette (whose then two-year old son had been diagnosed with cancer), the MACC Fund is the single largest private donor to MCW and the largest organizational donor to Children’s Hospital of Wisconsin – having provided a total of more than $45 million in support of basic science and clinical trials, as well as bringing research more quickly to the bedside and patient care. As a result of this exceptional generosity, Children’s named its pediatric oncology program the “MACC Fund Center” in 2013. Support from the MACC Fund also played a significant role in Children’s becoming the only designated Phase 1 Center for clinical trials in the state undertaken by the Children’s Oncology Group, and one of only 21 nationwide.

The MACC Fund established The MACC Fund Chair to recruit a distinguished researcher to MCW who would encourage the growth of our basic science investigations and further develop our translational research efforts with Children’s. Dr. Medin’s background as a research innovator and scientific leader make him uniquely well qualified to serve at the first MACC Fund Professor.

At MCW, Dr. Medin also will hold the titles of Vice Chair of Research Innovation for the Department of Pediatrics, and Research Director within the Section of Pediatric Hematology/Oncology – where he is expected to expand the Pediatric Hematology-Oncology-Transplant program. Further, Dr. Medin will serve as Director, Cell Processing Laboratories, Medical College of Wisconsin Adult and Pediatric Blood and Marrow Transplant Program. Dr. Medin also will hold appointments in the MCW Cancer Center and the Blood Research Center. Additionally, Dr. Medin will be the Good Manufacturing Practice (GMP) Facility Director. MCW is committed to building a state-of-the-art GMP facility (to serve as a campus-wide core), as cellular therapy is a priority for both the Department of Pediatrics and the MCW Cancer Center. Dr. Medin will assume his full duties on January 1, 2016.

Dr. Medin received a Bachelor of Science degree from the University of Wisconsin-Parkside in 1985. In 1991, he received a PhD in Biochemistry from the University of Kentucky, where he studied protein expression and enzymology. Dr. Medin was employed with the National Institutes of Health from 1992-1998, in the following roles: National Research Council Biotech Fellow with the Laboratory of Molecular Growth Regulation, National Institute of Child Health and Human Development (1992-1993); Intramural Research Fellow with the Molecular and Medical Genetics Section, Development and Metabolic Neurology Branch (DMNB), National Institute of Neurological Disorders and Stroke (NINDS) (1994-1996); and Senior Staff Fellow in the DMNB, NINDS (1996-1998). Among Dr. Medin’s areas of research at the NIH were gene transcription, Lysosomal Storage Disorders, and gene therapy.

From 1998-2001, Dr. Medin was Assistant Professor of Medicine and an Affiliate Member of the Department of Biochemistry and Molecular Biology at the University of Illinois at Chicago. Dr. Medin relocated to Toronto in 2001, where he held the following appointments: Scientist, Ontario Cancer Institute, Division of Stem Cell and Developmental Biology (2001-2006); Associate Professor, Department of Medical Biophysics, Faculty of Medicine, University of Toronto (2001-2008); Affiliated Scientists, Division of Experimental Therapeutics, Toronto General Research Institute (2001-2012); and Senior Scientist, Ontario Cancer Institute (2006-2012).

Dr. Medin’s laboratory currently focuses on the development and implementation of gene therapy using integrating viral vectors for inherited and acquired disorders. Dr. Medin has applied for 20 patents since

2001 and has co-registered 16 inventions during the past decade.

Dr. Medin has significant teaching experience as a lecturer, course coordinator and section leader, and is a member of the Curriculum Committee of the Department of Medical Biophysics at the University of Toronto. He has been a member of numerous American and Canadian scientific societies and advisory committees in areas such as Biochemistry, Gene Therapy, Molecular and Cellular Biology, Prostate Cancer, Breast Cancer, and Hematology. Additionally, Dr. Medin is an Academic Founder and member of the Scientific Advisory Board (SAB) of AvroBio LTD. He also is a member of the SAB of Plexera Therapeutics and an editorial board member of the World Journal of Stem Cells and Biomedicines. Dr. Medin has published more than 100 peer-reviewed papers, edited an immunotherapy book, and presented at more than 100 invited conferences and workshops.

We plan to work closely with Children’s and the MACC Fund to provide Dr. Medin with a generous introduction to the community. Please join us in welcoming Dr. Medin to MCW.

Sincerely,

Joseph E. Kerschner, MD
Dean of the School of Medicine
Executive Vice President
Medical College of Wisconsin

Marc H. Gorelick, MD, MSCE
Chief Operating Officer, Children's Hospital of Wisconsin
Executive VP, Children's Hospital and Health System
Professor of Pediatrics (Emergency Medicine), Medical College of Wisconsin

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  MACC Fund Center for Cancer and Blood Disorders

The MACC Fund Center for Cancer and Blood Disorders at Children's Hospital is among the most experienced and largest programs in the United States centering on a multidisciplinary approach to the care of patients with hematological, oncological, and immunological diseases. The Center is located near key resources and related disciplines to provide the most efficient, personalized and comprehensive care. These resources are enhanced by collaboration with partners such as the Medical College of Wisconsin and Blood Center of Wisconsin.

  BMT Program

The pediatric blood and marrow transplant program is a joint venture between the Medical College of Wisconsin (MCW) and Children's Hospital of Wisconsin (CHW). The pediatric BMT Program is an integral part of the continuously FACT accredited MCW BMT Program which is a joint program integrating the transplant teams and services of Children’s Hospital of Wisconsin, Froedtert Hospital, The BloodCenter and MCW. The pediatric BMT program, initiated in 1980, has performed more than 900 transplants. The program is one of the largest and most experienced in the U.S. utilizing alternative donors such as unrelated individuals or mismatched family members as donors.

  Oncology Program

The Oncology Program at the Children’s Hospital of Wisconsin is among the most experienced and largest, specializing in the treatment of children with a wide variety of cancers. The Oncology Program focuses on offering new discoveries to our patients through clinical trial participation in consortium groups such as Children’s Oncology Group (COG), industry trials and investigator-initiated studies. The multidisciplinary oncology team includes highly trained specialists to diagnose and treat children's cancer and to help children and their families through the process. This is clinical expertise is paired with basic scientists with research foci including tumor immunology, cell signaling pathways in brain tumors and mitigation of therapy related injury by small molecules.

  Hematology Program

The Hematology Program offers comprehensive services for the treatment of children, adolescents and adults with acute and chronic blood diseases. The program includes general hematology services, the Wisconsin Sickle Cell Center and the Comprehensive Center for Bleeding Disorders, which are internationally known for their clinical care and research expertise. The program is a nationally recognized, federally funded center of excellence for bleeding and thrombotic disorders, and includes one of the country's leading basic research programs in hemophilia and von Willebrand disease. The Wisconsin Sickle Cell Center provides services comprehensive care for adults and children with SCD while striving to be at the forefront of basic, translational and outcomes related research in sickle cell disease. The center is one of only 11 sites nationwide awarded a National Institutes of Health Basic and Translational Research Program (BTRP). For our entire Hematology faculty, there is a close intertwining of research interests with clinical work to bring the lab to the bedside and the bedside to the lab.

  Research Program

Multidisciplinary teams within the section take problems encountered in the clinic back to the laboratory to better understand cellular and molecular mechanisms, then returning to the clinic with improved treatment strategies. Active translational research programs include experimental hematopoietic progenitor cell transplantation, cancer immunotherapy, mechanisms of vaso-occlusion in sickle cell disease and bleeding disorders, and the diagnosis and treatment of vascular tumors and anomalies.

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Pediatrics Hematology/Oncology/BMT
Medical College of Wisconsin
Department of Pediatrics
8701 Watertown Plank Road
MFRC 3020
Milwaukee, WI 53226

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(414) 955-4170 | (414) 955-6543 (fax)
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(414) 262-2930

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(414) 262-2420

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(414) 266-4850

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8701 Watertown Plank Road
Milwaukee, WI 53226
(414) 955-8296
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