Pediatrics: Hematology Oncology BMT

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Research

The Division of Hematology/Oncology/Blood and Marrow has a long-standing commitment to basic and translation research that stems from the work carried out in our basic science laboratories, participation in co-operative group trials, as well as in epidemiology and outcomes research.

 

Basic Research Faculty

  • Andrew M. Chan, PhD - cancer cell signaling and developing mouse models of human gliomas.

  • Veronica H. Flood, MD - coagulation defects and von Willebrand disease.

  • Jill Gershan, PhD - development of cell-based vaccine for the treatment of breast cancer and breast cancer stem cells.

  • Joan C. Gill, MD - molecular and clinical biology of von Willebrand disease, coumadin pharmacogenetics in children, immunology of inhibitor formation in hemophilia, T-cell responses to hepatitis C synthetic peptides in HCV-infected hemophilic patients, replacement therapy in hemophilia.

  • Sandra L. Haberichter, PhD - cell biology and molecular mechanisms of von Willebrand disease.

  • Cheryl A. Hillery, MD - mechanisms of vaso-occlusion and vascular dysfunction in human and murine sickle cell disease, including roles of inflammation, coagulation pathways, hemolysis and oxidative injury. Effect of co-morbid asthma in murine and human sickle cell disease. Nociceptive mechanisms underlying sickle cell pain.

  • Bryon Johnson, PhD - bone marrow transplantation, immune memory, immune therapy for cancer, pediatric malignancies, neuroblastoma, tumor vaccines.

  • Robert R. Montgomery, MD - molecular and clinical biology of VWD, gene therapy of hemophilia.

  • Qizhen Shi, MD, PhD - hemophilia, the association between VWF and FVIII, gene therapy, immune response in hemophilia gene therapy.

  • Fritz Sieber, PhD - development of novel anti-cancer agents, prevention, and mitigation of damage to normal tissue in patients undergoing radiation therapy.

  • Nancy Wandersee, PhD - red blood cell membrane/membrane skeleton; hereditary spherocytosis and elliptocytosis; sickle cell disease; hemolysis and vascular injury;mouse models; pathophysiology of stroke, thrombosis, and vascular dysfunction

 

Research Affiliations

  • The Blood Research Institute of the BloodCenter of Wisconsin and the Pediatric Hematology/Oncology/Blood and Marrow Transplant Division at the Medical College of Wisconsin have an ongoing collaboration that has contributed to an invaluable network of scientific discovery and patient care.

  • The Center for International Blood and Marrow Transplant Research is a combined research program of the National Marrow Donor Program and the Medical College of Wisconsin working to collect and study data on blood and bone marrow transplants worldwide.  More than 500 international transplant centers collaborate with the CIBMTR to conduct research studies, collect, maintain, and share outcomes data on more than 300,000 transplant recipients, provide statistical expertise to researchers, and to provide education, guidelines, and training.

  • The Children's Research Institute advances state-of-the-art pediatric health care through translational research programs to find life-saving discoveries and cures in the disease that affect children and interventions that enhance quality of life for children and families living with chronic health conditions.

  • The Medical College of Wisconsin Cancer Center is the only academic-based cancer research and patient care group in Southeastern Wisconsin.  It is a matrix cancer center with clinical facilities at Froedtert Hospital, Children's Hospital of Wisconsin, and Zablocki VA Medical Center.

  • The MACC Fund, Midwest Athletes Against Childhood Cancer, Inc., a Milwaukee based charitable organization, works very closely with the Pediatric Hematology/Oncology/Blood and Marrow Transplant Division and the Medical College of Wisconsin to fight pediatric cancer and related blood disorders through research funding.  Since its inception in 1976, the MACC Fund has contributed nearly $30 million to the College’s pediatric cancer and blood disorder research.  This unique and exceptional affiliation provides researchers in the resources needed to fight against childhood cancer and related blood disorders.

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Page Updated 09/28/2012