Redox Biology Program

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Feb. 05, 2014

Redox Biology Program Awards Two Investigators Funding

The Medical College of Wisconsin (MCW) Redox Biology Program used its Advancing a Healthier Wisconsin (AHW) funding to award two Allison Ebert, PhD, and Andreas Beyer, PhD, $5,000 each for supplies and services for ‘new idea’ projects in the area of redox and oxidative biology.

Department of Cell Biology, Neurobiology and Anatomy Assistant Professor Allison Ebert will use her funding to buy supplies for her project, “Exploring Cell-Specific Mitochondrial Function in Neurological Disease.” The primary goal of her project is to determine if mitochondrial respiration can be measured in different cell types generated from pluripotent stem cells and if differences in respiration measures correlate to cell vulnerability in various neurodegenerative diseases.

Dr. Ebert, who earned a doctorate in neuroscience from Northwestern University, focuses on using induced pluripotent stem cells (iPSCs) derived from patient tissue to understand disease mechanisms and therapeutic intervention. Specifically, her lab is investigating the cell death processes involved in motor neuron loss in spinal muscular atrophy (SMA).

While the Ebert laboratory focuses on neurodegenerative diseases, Dr. Beyer’s group studies small blood vessels that control blood flow and the role of these vessels in cardiovascular diseases such as hypertension, coronary artery disease (CAD) and atherosclerosis.

Dr. Beyer, an assistant professor in the Department of Cardiovascular Medicine, will use his $5,000 to buy supplies for his project, “Role of Endothelial Telomerase Activity as a Novel Regulator of Redox Hemostasis.” His proposal focuses on endothelial changes in relation to cellular localization of the telomerase subunit TERT.

“The proposed investigations will provide useful, novel tool data for future application of external funding. We believe this project is of great value to the greater community and is applicable for multiple disease studies,” he said.

Both investigators received funding because their projects aligned with the AHW five-year plan research priorities.

Advancing a Healthier Wisconsin is an endowment of the Medical College of Wisconsin committed to improving the health of Wisconsin residents.

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Page Updated 07/01/2014