Redox Biology Program

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Fall 2013

The Redox Biology Program hosts a monthly "Works-in-Progress" session.

In addition, Albert Girotti, PhD, sponsors a noon to 1 p.m. Thursday journal club each week in Room 376 of the Biochemistry Department.

The focus of the Oxidative Signaling Journal Club is to examine recent manuscripts regarding oxidative signaling pathways with responses ranging from cell proliferation to cell senescence or death. Novel sensing mechanisms and sensor proteins responding to ROS or RNS redox are of particular interest.


Oxidative Signaling Journal Club


Date and Speaker Title
Sept. 20
Albert Girotti, PhD,

Department of Biochemistry
Sanuphan A, Chunhacha P, Pongrakhananon V, Chanvorachote P.(2013). Long-term nitric oxide exposure enhances lung cancer cell migration BioMed Research International, art. no. 186972  
Sept. 27
Bryndon Oleson
Graduate Student

Department of Biochemistry
Chung SS, Kim M, Lee JS, Ahn BY, Jung, HS, Lee HM, Park KS. (2011). Mechanism for antioxidative effects of thiazolidinediones in pancreatic β-cells American Journal of Physiology - Endocrinology and Metabolism, 301(5):E912-E921.
Oct. 4
Witek Korytowski, PhD
Assistant Professor

Department of Biochemistry
Kim J, Won JS, Singh AK, Sharma AK, Singh I. (2013). STAT3 Regulation by S-Nitrosylation: Implication for Inflammatory Disease. Antioxid Redox Signal.  [Epub ahead of print]
Oct. 11
Neil Hogg, PhD

Department of Biophysics
Director, Redox Biology Program
Balosso S, Liu J, Bianchi ME, Vezzani A. (2013). Disulfide-containing HMGB1 promotes NMDA receptor function and excitotoxicity by activating TLR4-dependent signaling in hippocampal neurons. Antioxid Redox Signal. [Epub ahead of print]
Oct. 18
John Corbett, PhD
Chairman and Professor

Department of Biochemistry
Tripathi DN, Chowdhury R, Trudel LJ, Tee AR, Slack RS, Walker CL, Wogan GN. Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1. Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):E2950-7. Epub 2013 Jul 22.

Oct. 25
Savitha Sethumadavan
Postdoctoral Fellow

Department of Biophysics

Nagalingam RS, Sundaresan NR, Gupta MP, Geenen DL, Solaro RJ, Gupta M.  A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling.  J Biol Chem. 2013 Apr 19;288(16):11216-32. Epub 2013 Feb 27.
Nov. 1
Albert Girotti, PhD

Department of Biochemistry
Nomuraa K, Leea M, Banksa C, Leea G, Morrissa BJ. (2013) An ASK1-p38 signalling pathway mediates hydrogen peroxide-induced toxicity in NG108-15 neuronal cells. Neuroscience Letters. 549: 163-167.
Nov. 8
Nov. 15
Ching-Fang Chang
Graduate Student

Department of Biophysics
Dec. 6
James P. Thomas, MD, PhD
Section Head and Professor

Solid Tumor Oncology
Department of Medicine
Dec. 13
Jung-Ja Kim
Department of Biochemistry



Work-in-Progress Session


Date and Speaker Topic
Sept. 5
Madelyn Hanson, PhD
Postdoctoral Fellow
Department of Biophysics
Neutrophils in Sickle Cell Disease: A Red Cell Disorder with a White Cell Problem
Nov. 7
Dorothee Weihrauch, DVM, PhD
Associate Professor
Department of Anesthesiology
When Good Matrix Goes Bad
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