1st Annual Organ Transplantation Research Retreat

October 2-3, 2013

On behalf of the Department of Surgery and the Solid Organ Transplantation (SOT) Joint Program at MCW-FH-CHW-BCW, Dr. Douglas B. Evans and Dr. Johnny C. Hong would like you to participate in the Surgical Grand Rounds and inaugural Organ Transplantation Research Retreat on October 2 and 3, 2013. For this year, Barry D. Kahan, PhD, MD, world renowned transplant surgeon and immunologist, is our SOT Visiting Professor.

Barry D. Kahan, PhD, MD served as Professor of Surgery and Director of the Division of Immunology and Organ Transplantation at The University of Texas Medical School at Houston and as Chief of the Organ Transplant Services at The Hermann Hospital in Houston for more than 30 years. He is currently Emeritus Professor and Director Emeritus of the Division of Immunology and Organ Transplantation at The University of Texas Medical School at Houston. He received both his PhD in physiology and his MD from the University of Chicago, and completed his internship and residency at Massachusetts General Hospital in Boston. Before his academic appointment at the University of Texas, Dr. Kahan held Assistant and Associate Professor positions in the Departments of Physiology and Surgery at Northwestern University Medical School in Chicago. He is Past President of the American Society of Transplant Surgeons.

Dr. Kahan is Editor-in-Chief of Transplantation Proceedings, serves on the editorial boards of numerous scientific publications, including Transplantation, Clinical Transplantation and Clinical Nephrology; and has acted as a consultant for several national advisory committees, including the F.D.A. Advisory Committees on Anesthesia and Life Saving Drugs, as well as on Antiviral and Immunosuppressive Agents. He served two terms on the Department of Health and Human Services Advisory Committee on Transplantation. One of the Top 100 Most Cited Researchers in the World (Clinical Medicine) according to the Institute for Scientific Information, Dr. Kahan has published more than 950 original research papers in such esteemed journals as The New England Journal of Medicine, Science, and The Lancet.

For more than three decades, Dr. Kahan has been actively engaged in the development of new immunosuppressive therapies to combat organ transplant rejection—cyclosporine and sirolimus. At present, he is interested in the development of synergistic immunosuppressive regimens. He was the first researcher to administer sirolimus to humans in pivotal clinical Phase I, II, and III trials of the drug to renal transplant recipients and subsequently applied a mathematical model, the median effect equation, to document synergy with cyclosporine in humans. Following FDA approval of sirolimus, Dr. Kahan identified FTY720 as a new synergistic agent with the cyclosporine-sirolimus regimen, and served as the lead investigator in the Phase I trials of multiple doses of this new agent. His recent investigations have focused on synthetic compounds that disrupt selectin-mediated cell surface interactions (such as a Phase I/II study being conducted on P-selectin antibody YSPSL) on second generation development of agents more selective in their actions on sphingosine-1-phosphate receptors than FTY720 and on lymphoid specific blockade of Janus kinase 3.

During his two- day visit on October 2 and 3, 2013, we invite you to participate in the following activities:

Wednesday, Oct. 2, 2013

7:30 a.m. to 8:30 a.m.

Surgical Grand Rounds

Location: Helfaer Auditorium, 1st Floor, Froedtert Hospital

“Surgical Challenges in Renal Transplantation: A 40 Year Journey”

Speaker: Barry D. Kahan, PhD, MD


9:00 a.m. to 5:00 p.m.

Organ Transplantation Research Retreat

Location: CHW East 6M Large Conference Room, 6th Floor, Children’s Hospital of Wisconsin

An interactive program that will showcase state of the art basic science and clinical/transplantation research works in organ transplantation and immunobiology by scientists and investigators from MCW, Froedtert Hospital, Children’s Hospital of Wisconsin and BloodCenter of Wisconsin.
A preliminary program is attached.


Thursday, Oct. 3, 2013

4:00 p.m. to 5:00 p.m.

Organ Transplantation Grand Rounds

Location: Helfaer Auditorium, 1st Floor, Froedtert Hospital

“Transplant Immunosuppression: Current State and Future Prospects”

Speaker: Barry D. Kahan, PhD, MD


We look forward to your participation in this year’s SOT Visiting Professor events. If you have any questions about this event, please feel free to contact Dana Schmidman, Program Coordinator II, Division of Education, Department of Surgery, at 414.805.5602 or Tracie Hutchison, Division of Transplant Surgery, at 414-955-6928.


Johnny C. Hong, MD, FACS
Associate Professor of Surgery
Mark B. Adams Chair in Surgery
Hepatobiliary Surgery & Organ Transplantation
Chief, Division of Transplant Surgery
Director, Solid Organ Transplantation

Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226
(414) 955-8296
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