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  3.0 Tesla GE Short-Bore Excite MRI System

The GE 3T MR750 system is a 60-cm bore, clinically certified MRI system that is dedicated to research. This scanner is housed at the Froedtert Pavillion and operated by the Center for Imaging Research. Visit the CIR's equipment page for additional details about this system.

  Mock Scanner

This resource mimics the spatial and aural environment of a functioning scanner. It is used for subject training and psychophysical studies. It is operated by the MCW General Clinical Research Center.

  9.4 T Bruker BioSpec 94/30 USR In-vivo Spectroscopy Imaging System

The Bruker BioSpec system has an actively shielded 9.4 Tesla magnet with a 31-cm warm bore. This system is operated by the Center for Imaging ResearchVisit the CIR's equipment page for additional details about this system.

  microSPECT/CT Scanner

This instrument is a hybrid four-detector microSPECT with integrated X-ray CT module (FLEX Triumph [microSPECT/CT], Gamma Medica – Ideas).

microCT

The integrated cone-beam X-ray CT system is situated on same axis as the SPECT system, providing attenuation correction and co-registered X-ray CT and SPECT tomographic images. Technical features of the CT are as follows: The X-OT, CT sub-system, is equipped with an advanced CMOS digital X-ray detector technology and has the flexibility to perform a wide range of scanning. The X-OTM system allows researchers to image a large range of test subjects with its 9.3 cm diameter by 9.7 cm axial field of view, 118.4 mm x 112 mm X-ray CMOS detector with 368 x 2240 pixels and 50 μm pitch X-ray generator tunable from 50 to 80 kVp. Scout View for graphically assigning acquisition and reconstruction ROIs.  Live Fluoro View for X-ray guided animal positioning.  Delivered X-ray dose is < 2 cGy (continuous rotation mode). User selectable CT reconstruction options optimize soft tissue contrast or spatial resolution. User selectable X-ray detector binning from 1 x 1 to 4 x 4 optimize resolution and scanning speed. Acquisition graphical user interface displays projection data during a scan. User is able to select step or continuous rotation scan mode.

microSPECT

Features of the microSPECT scanner include broadband NaI(Tl) SPECT detectors with user interchangeable multipinhole aperture plates and parallel hole collimators, and volumetric reconstruction with various filtering/reconstruction algorithms. The multipinhole (5 pinholes per detector) SPECT imaging will enable a sensitivity level of greater than 1000 cps/MBq for dynamic studies of fast kinetic biological events. The multiplexed SPECT imaging with overlapping image projections on the detectors allows a maximized image magnification with sub-mm spatial resolution. The system has gated imaging and list-mode with dynamic imaging capabilities for quantitative SPECT imaging and dual- and multi-isotope studies.

  Biochemical Equipment
  • Liquid nitrogen and liquid helium equipment
  • Update Instruments Precision Syringe-Ram
  • Hewlett-Packard 1050 Series HPLC with UV/visible, fluorescence, and electrochemical detection with HP station integration software
  • Hewlett-Packard 8453 general purpose UV/visible spectrophotometer with software for biochemical analysis, thermostat-controlled cell holder, and a Fisher refrigerated water circulator (Model 1006P)
  • Beckman Paragon Electrophoresis System
  • Microscopes
    • Zeiss fluorescence-microscopy photometer system
    • Nikon phase-contrast
    • Bausch & Lomb Stereo-Zoom 5
  • Centrifuges
    • Beckman Airfuge ultra-centrifuge
    • Sorvall RC-5B refrigerated superspeed centrifuge
  • Extruder (Lipex Biomembranes, Inc.) for preparation of liposomes
  • UV-VIS Light Sources
    • 200 W Hg high-pressure compact arc lamp (Oriel Model 6137)
    • 300 W XE high-pressure compact arc lamp (Eimac Model VIX 300UV)
  • Monochromator (Bausch & Lomb 33-86 Series)
  • Radiometer (Yellow Springs Instrument Model 65-A) for measurement of the fluence rate of the illuminating radiation
  • BioTek Instruments UV/visible microplate reader and fluorescence
  • Varian 3700 gas chromatograph unit with thermal conductivity detection
  • Jasco 710 spectropolarimeter
  • ABI 310 genetic analyzer
  • Insight II Molecular Modeling Environment including modules for molecular dynamics simulations, homology modeling and quantum mechanics engines
  Electronic Equipment

Extensive electronic test equipment including:

  • Agilent E5501B Phase Noise Measurement System
  • HP3577A Network Analyzer (5 Hz–200 MHz)
  • HP8510B Network Analyzer (10 MHz–20 GHz)
  • HP8722D Network Analyzer (50 MHz–40 GHz)
  • HP8566A Spectrum Analyzer (100 Hz–22 GHz)
  • HP8596E Spectrum Analyzer (9 KHz–12.8 GHz)
  • HP8564E Spectrum Analyzer (9KHz–40 GHz)
  • HP54100A Digitizing Oscilloscope
  • Frequency counters to 40 GHz
  • Ansoft High Frequency Structure Simulator (HFSS)
    • This state-of-the-art computer program running on an HP735 workstation is used for solution of Maxwell's equations. It permits objective (rather than intuitive) design of surface coils and may be useful for modeling rf field distributions in the brain during fMRI studies.
  Equipment for Small Animal Research
  • Two-channel dual probe, PO2, EEG, and laser Doppler flow monitor (Oxy Flo:Oxy Lite), Oxford Optronix Inc.
  • Laser-Doppler Flowmeter, EEG-recording, Oxford Array
  • Blood Gas Analyzer, Radiometer ABL3
  • Video Records (3), JVC
  • Small-Animal Ventilator, CWE 830
  • Rodent capnograph, Stoelting
  • Temperature controller, YSI 73A
  • Stereotaxic apparatus, Kopf 9001
  • Infusion pumps, Harvard Apparatus
  • Analytical balance, Mettler AB 104, H10T
  • Anesthetic monitor, Criticare POETII
  • Polygraph, Astro-Med MT 950001
  • Surgical microscope, Bausch & Lomb
  • North American Drager Anesthetic Vaporizers (3)
  • Medical gas analyzer, Perkin-Elmer 1100 FHC OTS
  • FM data recorder, A.R. Vetter 620 (2)
  • Black & white video camera Dage-MTI CCD –72
  • 10-channel polygraphs, Grass Model 7 (2)
  • Color video monitor Sony Trinitron PVM-1353
  • Microscope, Nikon Optiphot
  • X-ray developer and dark room
  • RC5B high speed centrifuge
  • Forma -80 degree freezer
  • Syringe pump, Harvard 4400
  • Reichert Jung Model 2200 cryostat
  • AIS Imaging Research Computerized Microdensitometer
  • S48 Stimulator, Grass Telefactor
  • Isoflurane Vaporizer, Model 100F

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