Biostatistics

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Biostatistics Consulting Service

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Faculty and students often work with the Consulting Service to provide researchers assistance with research studies.  Services offered include Planning, Data Collection, Analysis, and Reporting.

Recent Publications from Consulting Projects:

2009:

Publications:

Crosby MA, Tward JD, Szabo A, Lee CM, and Gaffney DK, Does brachytherapy improve survival in addition to external beam radiation therapy in patients with high risk stage I and II endometrial carcinoma?, International Journal of Gynecology and Obstetrics; [Submitted], 2009.

Dunn BE, Choi H, Recla DL, Kerr SE, and Wagenman BL, Robotic surgical telepathology between the Iron Mountain and Milwaukee Department of Veterans Affairs Medical Centers: A twelve year experience, Human Pathology; 40(8):1092-9, 2009.

Ellinas EH, Eastwood DC, Patel SN, and Maitra-D’Cruze AM, The effect of obesity on neuraxial anesthesia difficulty in pregnant patients: A prospective, observational study, Anesthesia & Analgesia; 109(4):1225-31.

Everson CA and Szabo A, Recurrent restriction of sleep and inadequate recuperation induce both adaptive changes and pathological outcomes, American Journal of Physiology: Regulatory, Integrative and Comparative Physiology; 2009 Aug 19 [Epub ahead of print].

Hitchcock YJ, Tward JD, Szabo A, Bentz BG, and Shrieve DC, Relative contributions of radiation and cisplatin-based chemotherapy to sensorineural hearing loss in head-and-neck cancer patients, International Journal of Radiation Oncology Biology Physics; 73 (3): 779-88, 2009.

Holzhauer JK, Reith V, Sawin KJ, and Yen K, Evaluation of temporal artery thermometry in children 3–36 months old, Journal for Specialists in Pediatric Nursing; 14 (4): 239-44, 2009.

Kandiah P, Jacob S, Dhruvil P, Roger F, Karczewski C, Tan M, Smith H, Dye A, Ahn KW, Khan A, and Nanchal R, Novel use of Dexmedetomidine in 7 adults with severe alcohol withdrawal syndrome in the ICU, Critical Care Medicine; [Submitted], 2009.

Klatt T, Factors associated with recurrent bacterial vaginosis, The Journal of Reproductive Medicine, [Accepted], 2009.

Konop KA, Strifling KM, Wang M, Cao K, Schwab JP, Eastwood D, Jackson S, Ackman JD, Harris GF, Upper extremity kinetics and energy expenditure during walker-assisted gait in children with cerebral palsy, Acta Orthopaedica et Traumatolociga Tucica; 43(2):156-64, 2009.

Konop KA, Strifling KM, Wang M, Cao K, Schwab JP, Eastwood D, Jackson S, Ackman JD, and Harris GF, A biomechanical analysis of upper extremity kinetics in children with cerebral palsy using anterior and posterior walkers, Gait and Posture; 30(3):364-9, 2009.

Korkor AB, Eastwood D, and Bretzmann C, Effects of gender, alcohol, smoking, and dairy consumption on bone mass in Wisconsin adolescents, Wisconsin Medical Journal; 108 (4): 181-188, 2009.

Liu Q, Wong-Riley MTT, Postnatal changes in the expressions of serotonin 1A, 1B, and 2A receptors in ten brain stem nuclei of the rat: Implication for a sensitive period, Neuroscience; 2009 Oct 2, [Epub ahead of print].

Long J, Harris G, Eastwood D, Graf A, and Wesley M, Repeatability and sources of variability in multi-center assessment of segmental foot kinematics in normal adults, Gait and Posture; [Accepted], 2009.

McGuire J, Szabo A, Jackson S, Bradley TG, and Okunseri C, Erosive tooth wear among children in the United States: Relationship to race/ethnicity and obesity, International Journal of Paediatric Dentistry; 19 (2):01-98, 2009.

McMullin BT, Rhee JS, Pintar FA, Szabo A, and Yoganandan N, Facial fractures in motor vehicle collisions:  Epidemiological trends and risk factors, Archives of Facial Plastic Surgery; 11(3):165-70, 2009.

Migrino RQ, Ahn KW, Brahmbhatt T, Harmann L, Jurva J, and Pajewski N, 2D strain echocardiography predicts segmental viability following myocardial infarction: Optimization using Bayesian spatial modeling, American Journal of Cardiology; 104(8):1023-9, 2009.

Migrino RQ, Christenson R, Szabo A, Bright M, Truran S, and Hari P, Prognostic implication of late gadolinium enhancement on cardiac MRI in light chain (AL) amyloidosis on long term follow up, BMC Medical Physics; 9:5, 2009.

Migrino R, Mareedu R, Eastwood D, Bowers M, Harmann L, and Hari P, Left ventricular ejection time on echocardiography predicts long-term mortality in light chain amyloidosis, Journal of the American Society of Echocardiography; [Accepted], 2009.

Nicolosi AC, Lilly RE, Cristoforo M, Almassi GH, Tarima S, Xiang Q, Iacovino D, Topical application of autologous platelet rich plasma does not reduce sternal wound infection after cardiac surgery, Annals of Thoracic Surgery; (submitted).

Noyce M, Szabo A, Pajewski NM, Jackson S, Bradley TG and Okunseri C, Primary language spoken at home and children’s dental utilization in the United States, Journal of Public Health Dentistry; 2009 Jun 22. [Epub ahead of print]

Okunseri C, Szabo A, Jackson S, Pajewski NM, and Garcia RI, Increased children’s access to fluoride varnish treatment by involving medical care providers: Effect of Medicaid policy change, Health Services Research; 44(4):1144-56, 2009.

Panepinto JA, Pajewski NM, Foerster LM, Sabnis S, and Hoffmann RG, Impact of family income and sickle cell disease on the health-related quality of life of children, Quality of Life Research; 18 (1):5-13, 2009.

Salzman NH, Hung K, Haribhai D, Chu H, Karlsson-Sjöberg J, Amir E, Teggatz P, Barman M, Hayward M, Eastwood D, Stoel M, Zhou Y, Sodergren E, Weinstock GM, Bevins CL, Williams C, and Bos NA, Enteric defensins are essential regulators of intestinal microbial ecology, Nature Immunology, 2009 Oct 22. [Epub ahead of print]

Smith PA, Hassani S, Graf A, Flanagan A, Reiners K, and Harris GF, Brace evaluation in children with diplegic cerebral palsy with a jump gait pattern, Journal of Bone and Joint Surgery; 91(2):356-65, 2009.

Stiehl J, Long-term periprosthetic remodeling in THA shows structural preservation, Clinical Orthopaedics and Related Research; 467(9):2356-61, 2009.

Stiehl JB, Jackson S, and Szabo A, Multi-factorial analysis of time efficiency in total knee arthroplasty, Computer Aided Surgery; 26:1-5, 2009.

Storvik SG, Stemper BD, Yoganandan N, and Pintar FA, Population-based estimates of whiplash injury using nass cds data - biomed 2009, Biomedical Sciences Instrumentation; 45:244-9, 2009.

Trivedi H, Daram S, Szabo A, Bartorell AL and Marenzi G, High-Dose N-acetylcysteine for the Prevention of Contrast-induced Nephropathy, American Journal of Medicine; 122(9):874.e9-15, 2009.

Trivedi H, Xiang Q, and Klein JP, Risk Factors for Non-fatal myocardial infarction and cardiac death in incident dialysis patients, Nephrology and Dialysis Transplantation; 24(1):258-66, 2009.

Zhang R, Mio Y, Pratt PF, Lohr N, Warltier DC, Whelan HT, Zhu D, Jacobs ER, Medhora M, and Bienengraeber M, Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanism, Journal of Molecular and Cellular Cardiology; 46(1):4-14, 2009.

Zhi H, Yang XJ, Kuhnmuench J, Berg T, Thill R, Yang H, See WA, Becker CG, Williams CL and Li R, SmgGDS is up-regulated in prostate carcinoma and promotes tumour phenotypes in prostate cancer cells, Journal of Pathology; 217 (3):389-97, 2009.

Presentations/Abstracts:

Aufderheide TP, Lurie KG, Yannopoulos D, Allen SG, Pirrallo RG, Dye AM, Klein JP, and Provo TA, Ventilation Rate and Use of the Impedance Threshold Device are Correlated with Hemodynamics During CPR in Humans, Resuscitation Science Symposium and Scientific Sessions; Orlando, FL, Nov 2009. **AHA 2009 Resuscitation Best Abstract Award**

Bergom C, Kelly T, Xiang Q, Ahn KW, Morrow N, Wilson JF, and White J, Failure patterns after 3D conformal radiotherapy for whole breast irradiation in the prone position, Poster Session, Annual Meeting & Program Committee of the American Society for Radiation Oncology, Chicago, IL, Nov 2009.

Brinkerhoff B, Campbell B, Tripp P, Wong S, Pasquini M, Dye A, and Choong N, Impact of delaying initiation of chemoradiotherapy in patients with advanced-stage squamous cell carcinoma of the head and neck, Poster session, Multidisciplinary Head and Neck Cancer Symposium, February 25-27, 2010.

Brown J, Mulberry M, Margolis D, Eastwood D, Ahn KW, and Talano J, Comparing the incidence of veno occlusive disease of the liver in pediatric bone marrow transplant patients with heparin alone vs. heparin and ursodiol prophylaxis, Poster Presentation, 3rd Department of Pediatrics Summer Research Student Fair, August 2009.

Fullerton J, Kim J, Xiang Q, and Szabo A, Comparison of spectral domain OCT and time domain OCT for measurements of retinal thickness, Association for Research in Vision and Ophthalmology, Annual Meeting, Fort Lauderdale, FL, 2009.

Long J, Eastwood D, and Harris G, Inter-site Reliability of Multisegmental Foot Kinematics Assessed with the Milwaukee Foot Model (MFM), American Academy Of Orthopaedic Surgeons AAOS Annual Meeting Las Vegas, NV; February 22-25, 2009.

Migrino RQ, Harmann L, Brahmbhatt T, Jurva J, and Pajewski N, 2D strain echocardiography predicts segmental myocardial viability in coronary artery disease: Optimization using Bayesian logistic spatial modeling, Abstract American Society of Echocardiography meeting, June 2009.

Okunseri C, Pajewski NM, Jackson S, and Szabo A, Frequent users of emergency departments and physician offices for non traumatic dental conditions among Wisconsin Medicaid enrollees, 137th APHA Meeting and Exposition, November 2009.

Okunseri C, Szabo A, Jackson S, Pajewski N and Garcia R, Provision of Fluoride Varnish in Dental Health Professional Shortage Areas, International Organization for Dental Research, Miami, FL, 2009.

Pandya DJ, Lynch JR,Fitzsimmons BF, Kandiah PA, Wolfe T, Hussain S, and Zaidat OO, Safety and efficacy of second coil embolization for remnant intracranial aneursym after initial endovascular therapy, American Academy of Neurology, annual meeting, Seattle, 2009.

Patel A, Gawrieh S, Rizvi S, Xiang Q, Szabo A and Saeian K, Management Strategies Used for Nonalcoholic Fatty Liver Disease: Survey of AASLD Members, American Association for the Study of Liver Disease Digestive Disease week,  May 2009.

Radzienda M, Conti M, Szabo A, and Jackson S, Impact of behavioral modification on lab test utilization at an academic medical center, poster presentation at the Society of Hospital Medicine’s annual meeting; Chicago, IL, May 2009.

Samuels TL and Johnston N,  Pepsin as a causal agent of inflammation during nonacidic reflux, Otolaryngology - Head and Neck Surgery;  Annual Meeting of the American Academy of Otolaryngology-Head and Neck Surgery, San Diego, CA, Oct 4-7, 2009.

Self K, Girgis D, Jackson S, Tarima S, McGinley E, Abena A, and Okunseri CE, Perceived need for dental care among homeless persons in America. International Association of Dental Research, Miami, FL, Apr 2009.

Slavens B, Eastwood D, Sturm P, and Harris G, Lofstrand Crutch-Assisted Gait in Children with Myelomeningocele: Clinical Outcomes Assessment and Upper Extremity Dynamics, RESNA 2009 Annual Conference, New Orlens, LA, June 2009.

Storvik SG, Stemper BD, Yoganandan N, and Pintar FA Population-based estimates of whiplash injury using NASS CDS data - BIOMED 2009, 46th annual Rocky Mountain Bioengineering Symposium, 2009

Szabo A, Statistical Modeling for Biological Systems:  A Conference in Memory of Andrei Yakovlev, University of Rochester, NY, June 2009.

Tarima SS, Eastwood D, Xiang Q, Maguire A, The use of hierachical weighted least squares for multi-source parameter estimation: Analysis of Wisconsin unemployment data, 12th CDC/ATSDR Symposium on Statistical Methods, Decatur, GA, Apr 2009.

Yan J, Samuels TL, and Johnston N, Pepsin, at pH7 – in non-acidic laryngopharyngeal refluxate, significantly alters the expression of multiple genes implicated in carcinogensis, Annals of Otology, Rhinology, and Laryngology; Annual Meeting of the American Broncho-Esophagological Association, Bally's Las Vegas, Las Vegas, NV, April 28–May 2, 2010.

2008:

Publications:

Barman M, Unold D, Shifley K, Amir E, Hung K, Bos N and Salzman N, Enteric salmonellosis disrupts the microbial ecology of the murine gastrointestinal tract, Infection and Immunity; 76(3), 907-15, 2008.

Brown AP, Chen J, Hitchcock YJ, Szabo A, Shrieve DC, and Tward JD, The risk of second primary malignancies up to three decades after the treatment of differentiated thyroid cancer, Journal of Clinical Endocrinology & Metabolism; 93(2):504-15, 2008.

Del Bene F, Wehman AM, Link BA, and Baier H, Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradient, Cell; 134(6):1055-65, 2008.

Etzioni R, Tsodikov A, Mariotto A, Szabo A, Falcon S, Wegelin J, Ditommaso D, Karnofski K, Gulati R, Penson D, and Feuer E, Quantifying the role of PSA screening in the US prostate cancer mortality decline, Cancer Causes and Control; 19(2):175-81, 2008.

Kutty S, Brown K, Asnes JD, Rhodes JF and Latson, LA, Causes of recurrent focal neurologic events after transcatheter closure of patent foramen ovale with the CardioSEAL septal occluder, American Journal of Cardiology; 101(10), 1487-92, 2008.

Kutty S, Brown K, Qureshi AM, and Latson LA, Maximal potential patent foramen diameter does not correlate with the type or frequency of the neurologic event prior to closure, Cardiology; 113(2):111-115, 2008.\

Liu Q, Fehring C, Lowry TF and Wong-Riley MTT, Postnatal development of metabolic response to normoxia and acute hypoxia in rats: implication for a sensitive period, Journal of Applied Physiology; 106(4):1212-22, 2008.

Mio Y, Bienengraeber MW, Marinovic J, Gutterman DD, Rakic M, Bosnjak ZJ and Stadnicka A, Age-related attenuation of isoflurane preconditioning in human atrial cardiomyocytes: Roles for mitochondrial respiration and sarcolemmal adenosine triphosphate-sensitive potassium channel activity, Anesthesiology; 108(4):612-20, 2008.

Okunseri C, Pajewski NM, Brousseau DC, Tomany-Korman S, Snyder A, and Flores G, Racial and ethnic disparities in nontraumatic dental-condition visits to emergency departments and physician offices: A study of the Wisconsin Medicaid program, Journal of American Dental Association; 139(12):1657-66, 2008.

Panepinto JA, Pajewski NM, Foerster LM, and Hoffmann RG, The performance of the PedsQL generic core scales in children with sickle cell disease, Journal of Pediatric Hematology/Oncology; 30(9):666-73, 2008.

Rebella GS, Edwards JO, Greene JJ, Husen MT, and Brousseau DC, A prospective study of injury patterns in high school pole vaulters, The American Journal of Sports Medicine; 36(5):913-20, 2008.

Samuels TL, Handler E, Syring ML, Pajewski NM, Blumin JH, Kerschner JE, and Johnston N, Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux, Annals of Otolaryngology, Rhinology and Laryngology;117(9):688-95, 2008.

Sudakoff GS, Dunn DP, Guralnick ML, Hellman RS, Eastwood D, and See WA, Multidetector computerized tomography urography as the primary imaging modality for detecting urinary tract neoplasms in patients with asymptomatic hematuria, Journal of Urology; 79(3):862-7, 2008.

Szabo A and Boucher K, Oncogenetic trees, In Handbook of Cancer Models with Applications, eds Tan & Hanin; World Scientific, 2008.

Whitesides J, Pajewski NM, Bradley TG, Iacopino AM, and Okunseri C, Socio-demographics of adult orthodontic visits in the United States, American Journal of Orthodontics Dentofacial Orthopedics; 133(4):489.e9-14, 2008.

Presentations/Abstracts:

Brandow AM, Brousseau DC and A PJ, Functional Outcomes of Children with Sickle Cell Disease Treated for Vaso-Occlusive Painful Events, MCW Department of Pediatrics poster session; 2008.

Guralnick M, Grimsby G, Liss M, Szabo A and O'Connor RC, Correlation between urgency score, voiding diary and urodynamics, International Continence Society, Cairo, Egypt, 2008.

Guralnick M, Grimsby G, Liss M, Szabo A and O'Connor RC, Objective Differences Between Overactive Bladder Patients With And Without Urodynamically Proven Detrusor Overactivity, Society for Urodynamics and Female Urology; 2008.

Guralnick M, Grimsby G, Liss M, Szabo A and O'Connor RC, Urge Score Correlations With Urodynamics In Women With Overactive Bladder, Society for Urodynamics and Femal Urology; 2008.

Kalia J, Hussain S, Wolfe T, Kabbani M, Zaidat OO, American Academy of Neurology - 61st Annual Meeting Sensitivity and Specificity Analysis of CT Angiography for diagnosis of Atherosclerotic Diseases in Head and Neck Vessels American Academy of Neurology - 61st Annual Meeting, 2008.

Laud PW and Pajewski NM, Genetic Association Studies in the Presence of Population Structure Invited colloquium talk at the University of Kentucky. September 2008.

Long JT, Wang M, Winters JM, Harris GF, and Gerald F, A multisegmental foot model with bone-based referencing: Sensitivity to radiographic input parameters, Engineering in Medicine and Biology Society, 2008: 30th Annual International Conference of the IEEE; 879-882, 2008.

McGuire AM, Xiang Q, Eastwood D, and Tarima S, Health related barriers to employment: data from a welfare reform program, American Journal of Epidemiology; 41st meeting of the Society of Epidemiologic Research; 167:S83, 2008.

McMullin BT, Rhee JS, Pintar FA, Szabo A and Yoganandan N, Facial fractures in motor vehicle collisions: Epidemiological trends and risk factors, American Academy of Facial Plastic and Reconstructive Surgery, Chicago, IL, contributed talk, 2008.

Migrino RQ, Phillips SA, Bright M, Wang J, Pajewski N, Prost R, and Hari P, Adverse functional significance of delayed enhancement on cardiac MRI in primary systemic amyloidosis, Abstract Society for Cardiovascular Magnetic Resonance Scientific Session, Los Angeles, CA, Feb 2008.

Migrino RQ, Bright M, Pajewski N, Truran S, Gutterman DD, and Hari P, Late gadolinium enhancement on MRI is a prognostic marker of poor survival in light chain amyloidosis: Results from long-term follow up, Circulation; 118 (18): S718, 2008.

Migrino RQ, Pajewski N, Bright M, Malmsten C, Harmann L, and Hari P, Echocardiographic Predictors of 1-Year Mortality in Light Chain AL Amyloidosis, Journal of Cardiac Failure; 14(6 Supp 1):S93-S94, 2008.

Okunseri C, McGuire J, Jackson S, Bradley G and Szabo A, Factors Associated with Dental Erosion Among Children in the U.S., International Association for Dental Research Annual Meeting, Toronto, Canada, 2008.

Okunseri C, Noyce M, Jackson S, Pajewski NM, Bradley TG and Szabo A, Effect of Parental Language Spoken at Home on Children's Preventive and Regular Dental Services Utilization in the United States, American Public Health Association Annual Meeting, San Diego, CA, 2008.

Okunseri C, Pajewski N, Szabo A, Bradley T and Noyce M, The Effect of Parental Language Spoken at Home on Children's Preventive and Regular Dental Services Utilization in the United States, Academy Health 2008 Annual Research Meeting, poster, 2008.

Okunseri C, Szabo A, Jackson S, Pajewski N and Garcia R, Provision of Fluoride Varnish in Dental Health Professional Shortage Areas, International Organization for Dental Research, Miami, FL, 2009.

Pajewski NM, Panepinto JA, and Laud PW, A Bayesian Nonparametric Model for Health-Related Quality of Life Outcomes, Poster presentation at Bayesian Biostatistics Conference, M.D.Anderson, Cancer Center, Houston, Texas. January 2008.

Patel A, Gawrieh S, Rizvi S, Xiang Q, Szabo A and Saeian K, Management Strategies Used for Nonalcoholic Fatty Liver Disease: Survey of AASLD Members, American Association for the Study of Liver Disease, Digestive Disease week, 2008.

Slavens BA, Sturm PF, and Harris GF, Upper extremity kinetics of children with myelomeningocele during Lofstrand crutch-assisted gait, Engineering in Medicine and Biology Society, 2008: 30th Annual International Conference of the IEEE; 20-25 Aug 2008: 4583-4586.

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