Cancer Center

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Cancer Center Seed Grant Awardees 

During FY13, the MCW Cancer Center will award well over $1 Million in peer-reviewed research grants to its members.  This includes previously awarded grants for Novel Cancer Research Grants, American Cancer Society Pilot Research Grants, and Large Center Planning Grants as well as new grants from the Rosenberg Family and Froedtert Hospital Foundation, and seed grants from the Cancer Center research programs.  

 
Dr. Robert Truitt, Cancer Center associate director of research resources, was instrumental in developing the Cancer Center seed grant program and portfolio, and in reviewing and awarding cancer-related seed funding.  Dr. Truitt is retiring on June 30.  His work with the Cancer Center has helped develop new projects, young investigators, and new science in the prevention, causes, detection, and treatment of cancer. 

Thank you Dr. Truitt, and congratulations to all of the awardees.  

 


THOMAS A. and LORRAINE M. ROSENBERG AWARD FOR TRANSLATIONAL CANCER RESEARCH ($80,000 for 2 years)

  • Denise Uyar, MD, Associate Professor of Obstetrics and Gynecology, with James Verbsky, MD, PhD (Pediatrics) and Martin Hessner, PhD (Pediatrics)

“Serum Induced Gene Expression Analysis and Endometrial Cancer”


LARGE CENTER PLANNING GRANTS ($100,000 each)

"Leukemia: Molecular and Cellular Mechanisms of Pathogenesis and Immunotherapy"

  • Demin Wang, PhD, Senior Investigator, Blood Research Institute
  • Sridhar Rao. MD, PhD, Assistant Professor, Department of Pediatrics
  • Subra Malarkannan, PhD, Associate Professor, Department of Medicine
  • Monica Thakar, MD, Assistant Professor, Department of Pediatrics

“Mechanisms, Treatment and Prevention of Metastasis in Breast Cancer”

  • Carol Williams, PhD, Professor, Department of Pharmacology & Toxicology
  • Alan Bloom, PhD, Professor, Department of Pharmacology & Toxicology
  • Chris Chitambar, MD, Professor, Department of Medicine
  • Mike Dwinell, PhD, Associate Professor, Department of Microbiology & Molecular Genetics
  • Balaraman Kalyanaraman, PhD, Professor & Chair, Department of Biophysics

WISCONSIN BREAST CANCER SHOWHOUSE BASIC SCIENCE SEED GRANTS IN BREAST or PROSTATE CANCER

($50,000 for 1 year)

  • Haris Vikis, PhD, Assistant Professor, Department of Pharmacology 

"Evaluation of Myeloperoxidase in Mediating the Anti-Metastatic Effects of Neutrophils in Breast Cancer"

  • Qing (Robert) Miao, PhD, Assistant Professor, Department of Pediatric Surgery

“Roles of Nogo-B Receptor (NgBR) in Breast Cancer Initiation and Progression”

  • Yan-Qing Ma, PhD, Associate Investigator, Blood Research Institute, BloodCenter of Wisconsin

“Kindlin-2 is a Novel Target for Breast Cancer Therapeutics” 


NOVEL CANCER RESEARCH GRANTS ($30,000 for 1 year)

  • Andrey Sorokin, PhD, Professor, Department of Medicine 

“Novel Regulation of Cox-2 Activity in Prostate Cancer”

  • Brian A. Link, PhD, Professor, Department of Cell Biology, Neurobiology & Anatomy

“Using Zebrafish to Characterize Hippo Pathway Associated Genes in Cancer”

  • Sam T. Hwang, MD, PhD, Professor and Chairman, Department of Dermatology, with Chris Chitambar, MD, Professor of Medicine and Xuesong Wu, MD, PhD, Postdoctoral Fellow

“Novel Gallium Compound as Mono- and Combination Therapy for Treatment of Cutaneous T Cell Lymphoma”

  • Jay Tichelaar, PhD, Assistant Professor, Department of Pharmacology & Toxicology

“Role of CCR4 in Lung Tumor Immune Surveillance”


AMERICAN CANCER SOCIETY PILOT RESEARCH GRANTS ($30,000 for 1 year)

  • Jeanne Palmer, MD, Assistant Professor, Department of Medicine (Hem/Onc)

“A Phase II Study of Tocilizumab for Steroid Refractory Chronic GVHD”

  • Matthew Riese, MD, PhD, Assistant Professor, Department of Medicine (Hem/Onc)

“Targeting Diacylglycerol Kinases toward Enhancing Anti-Tumor Responses in vivo in CAR-Transduced T Cells”

  • Jennifer M. Knight, MD, Assistant Professor, Department of Psychiatry

“The Impact of Socioeconomic Status on Gene Expression in Leukocytes of Hematopoietic Stem Cell Transplant Recipients”

  • Bin Ren, MD, PhD, Assistant Professor, Department of Medicine (Hem/Onc) and BRI

“Epigenetic Regulation of Endothelial Cell CD36 Transcription by Lysophosphatidic Acid and Angiogenesis in Breast Cancer in Diet-induced Obese Mice”

  • Sridhar Rao, MD, PhD, Associate Investigator, BRI, and Assistant Professor of Pediatrics

“Identifying Shared Transcriptional Programs between Leukemic and Embryonic Stem Cells”

  • Lauren A. Wiebe, MD, Assistant Professor, Department of Medicine

“ePRO Data for Patients Receiving Chemotherapy for GI Cancer”


BASIC SCIENCES RESEARCH PROGRAM SEED GRANTS  ($50,000 for 1 year)

  • Vera Tarakanova, PhD, Assistant Professor, Department of Microbiology & Molecular Genetics, with John Corbett, PhD, Professor and Chair, Department of Biochemistry and Neil Hogg, PhD, Professor, Department of Biophysics

“Manipulation of Oxidative Stress in Gammaherpesvirus Infection”

  • Paula Traktman, PhD, Professor & Chair, Microbiology & Molecular Genetics and Alexander Craig MacKinnon, MD, Assistant Professor, Department of Pathology

“The Role of the Protein Kinase VRK1 in Human (Breast) Cancer”

  • Hartmut Weiler, PhD, Associate Professor, Department of Physiology and Demin Wang, PhD, Senior Investigator, Blood Research Institute

“Role Gimap5 In Mitochondrial Metabolism of Chronic Myeloid Leukemia Stem Cells”

  • Jill Gershan, PhD, Assistant Professor, Department of Pediatrics and Ramani Ramchandran, PhD, Professor, Department of Pediatrics

"Identification of Factors that Promote Invasion and Metastasis of Epithelial Tumor Cells."

  • Dian Wang, MD, PhD, Professor, Department of Radiation Oncology, MCW and Liang Wang, MD, PhD,  Department of Pathology 

“Finding of Exosomal RNAs that Predict Prostate Cancer Response to Hormone Therapy”


CANCER IMAGING PROGRAM SEED GRANTS ($10,000-$20,000 for 1 year)

  • X. Allen Li, Professor, Department of Radiation Oncology, with Tian Liu, PhD (Emory Univ.), Kal Fishman, CTO (Sensus Healthcare), and J. Frank Wilson, Professor & Chair (Radiation Oncology)

“Feasibility of Ultrasound Image Guided Superficial Radiation Therapy for Skin Cancer”

  • Mohit Maheshwari, MD, Assistant Professor, Department of Radiology, with Andrew Foy, MD (Neurosurgery), James Joers, PhD (Radiology), Sarchin Jogal, MD (Pediatrics), Teresa Kelly, MD (Radiology), and Jennifer Koop, PhD (Neurology) 

“Utility of DTI and MR Perfusion Parameters of Brain White Matter in Predicting Neurocognitive Changes in Pediatric Patients following Treatment of Cerebellar Tumors”

  • Marcio Malogolowkin, MD, Professor & Chief, Pediatric Hematology/Oncology/Transplant with Michael Kelly, MD, PhD (Pediatrics), Kathleen Schmainda, PhD (Radiology & Biophysics), Jason Jarzembowski, PhD (Pediatrics), James Joers, PhD (Radiology), and Peter La Violette, PhD (Biophysics)

“Diffusion-Weighted Imaging to Evaluate Cellularity of Solid Tumors in Children, Adolescents and Young Adults”


POPULATION SCIENCES PROGRAM SEEDS GRANTS ($25,000 for 1 year) 

  • Rafael Santana-Davila, MD, Assistant Professor, Department of Medicine

"How Do Patients with Metastatic Lung Cancer and their Oncologists Make Decisions about using Palliative Chemotherapy” 

  • Tina W. Yen, MD, MS, Associate Professor, Department of Surgery

"Variations in Patterns of Breast Cancer Care by Hospital Volume”


HEMATOLOGIC MALIGNANCY AND TRANSPLANTATION PROGRAM SEED GRANTS ($15,000 for 1 year)

  • Marcelo Pasquini, MD, Associate Professor, Department of Medicine, Hematology and Oncology

“Temporal Expression Analysis of PD-1 on T cells and PD-L1 on Plasma Cells in Bone Marrow from Patients with Myeloma”

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