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Selected Publications:
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Van Orman JR, Si-Tayeb K, Duncan SA, Lough J. (2009) Induction of cardiomyogenesis in human embryonic stem cells (hESCs) by hESC-derived definitive endoderm. In Revision, 2009
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Zhao M, Barron MR, Li Z, Koprowski S, Hall CL, Lough J. Making Stem Cells Infarct Avid. In press, In press, Cell Transplant., 2009
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Rufer ES, Hacker T, Flentke GR, Drake VJ, Brody MJ, Lough J, Smith SM. Altered Cardiac Function and Ventricular Septal Defect in Avian Embryos Exposed to Low-Dose Trichloroethylene. In press, Toxicol. Sci., 2009
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Hu Y, Fisher JB, Koprowski S, McAllister D, Kim MS, Lough J. Homozygous disruption of the Tip60 gene causes early embryonic lethality. Dev. Dynamics 238:2912-2921, 2009
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Van Orman JR, Weihrauch D, Warltier DC, Lough J. Myocardial interstitial fluid inhibits proliferation and cardiomyocyte differentiation in pluripotent embryonic stem cells. Am J Physiol Heart Circ Physiol. 297:H1369-1376, 2009
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Li Z, Barron MR, Lough J, Zhao M. Rapid single-step separation of pluripotent mouse embryonic stem cells from mouse feeder fibroblasts. Stem Cells Dev. 17:383-387, 2008
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Gorrini C, Squatrito M, Wark L, Martinato F, Sardella D, Bennett S, Marchesi F, Scanziani E, Mai S, Lough J, Amati B. Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response. Nature 448:1063-1067, 2007
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Nelson TJ, Ge ZD, Van Orman J, Barron M, Rudy-Reil D, Hacker TA, Misra R, Duncan SA, Auchampach JA, Lough JW. Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells. Anat Rec 288:1216-1224, 2006
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Kim, M-S, X Merlo, C Wilson and J Lough. Co-activation of the atrial natriuretic factor promoter by Tip60 and serum response factor. J Biol Chem 281:15082-15089, 2006.
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Rudy-Reil D and J Lough. Avian precardiac endoderm/mesoderm induces cardiac myocyte differentiation in murine ES cells. Circ Res 94:e107-e116, 2004.
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Wendler CC, A Schmoldt, GR Flentke, LC Case, L Quadro, WS Blaner, J Lough and SM Smith. Increased fibronectin deposition in embryonic hearts of retinol-binding protein-null mice. Circ Res 92:920-928, 2003.
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