Human Vascular Function Affinity Group
The Cardiovascular Center has initiated AFFINITY GROUPS to stimulate and foster greater interaction and collaborations between CVC investigators and other investigators from MCW departments and outside institutions, such as Marquette University, the University of Wisconsin Milwaukee and the University of Georgia.
This group includes Michael Earing, MD, David Gutterman, MD, Anne Hoch, DO, Srividya Kidambi, MD, Margaret Samyn, MD, David Saudek, MD, J.C. Smith, Scott Strath, PhD, Denise Teves, MD, and Michael Widlansky, MD, MPH. The group centers its research efforts on applying tools to measure the health of blood vessels to determine novel inﬂuences on blood vessel health. These tools, including high-resolution ultrasound and pulse analysis, have been shown to be able to predict the risk for future heart attacks and strokes. Studies being performed by investigators in this group include:
- Determination of the effects of increasing physical activity on blood vessel function.
- Assessment of the effect of Vitamin D supplements on blood vessel function in patients with kidney disease.
- Determination of the importance of alterations in mitochondria (an important cell component) on blood vessel function in persons with diabetes.
- Measurement of the impact of increases in moderate physical activity on blood vessel function in healthy older adults.
- Determination of the mechanisms of blood vessel dysfunction in humans with high blood pressure.
Many of these studies look to determine:
- Whether novel mechanisms of heart attacks and strokes discovered in animal models or isolated cell studies are relevant to human vascular physiology; and/or
- Whether novel associations between risk factors and heart disease from large population studies are linked through alterations in the health of blood vessels.
These studies are performed by researchers from a large variety of disciplines, including adult and pediatric Cardiology, adult and pediatric Endocrinology, Orthopedic Surgery, Exercise Physiology, and Nephrology. The group includes investigators based both at the Medical College of Wisconsin and the University of Wisconsin-Milwaukee.
This group continues to grow its collaborative networks, leveraging the extensive assets of the Cardiovascular Center to translate novel ﬁndings into the realm of human subjects’ research.
Cardiovascular Annual Report 2010
Contact the CVC for additional information