Gyujoon (Guy) Hwang, PhD

Publications

• Accelerated brain aging in prolonged grief disorder of later life: Influence of comorbid depression.

  (Hwang G, Blair NO, Claesges SA, Reynolds CF, Davatzikos C, Goveas JS.) J Affect Disord. 2026 Jun 01;402:121387 PMID: 41690630 SCOPUS ID: 2-s2.0-105030017096 02/15/2026

• Prolonged grief disorder in later life: advancing our understanding of biopsychosocial mechanisms to guide future personalized interventions.

  (Goveas JS, Hwang G, Blair NP, Stein EA, Reynolds CF.) Neuropsychopharmacology. 2026 Jan 23 PMID: 41577994 SCOPUS ID: 2-s2.0-105028578296 01/24/2026

• Iyengar yoga and health education interventions for prolonged grief disorder in later life: feasibility of a randomized controlled pilot trial.

  (Goveas JS, Hwang G, McAuliffe TL, Blair NP, Webber A, Claesges SA, Murphy LM, Chandler K, Reynolds CF, Hainsworth KR.) Sci Rep. 2025 Dec 24;15(1):44604 PMID: 41444366 PMCID: PMC12738772 SCOPUS ID: 2-s2.0-105025806898 12/25/2025

• Amygdala-Centered Emotional Processing in Prolonged Grief Disorder: Relationship With Clinical Symptomatology.

  (Hwang G, Blair NP, Ward BD, McAuliffe TL, Claesges SA, Webber AR, Hainsworth KR, Wang Y, Reynolds CF, Stein EA, Goveas JS.) Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Dec;10(12):1284-1293 PMID: 39725082 PMCID: PMC12185774 SCOPUS ID: 2-s2.0-105000420540 12/27/2024

• DLMUSE: Robust Brain Segmentation in Seconds Using Deep Learning.

  (Bashyam VM, Erus G, Cui Y, Wu D, Hwang G, Getka A, Singh A, Aidinis G, Baik K, Melhem R, Mamourian E, Doshi J, Davison A, Nasrallah IM, Davatzikos C, Alzheimer’s Disease Neuroimaging Initiative, iSTAGING Consortium.) Radiol Artif Intell. 2025 Nov;7(6):e240299 PMID: 40960397 PMCID: PMC12661376 09/17/2025

• Neuroimaging endophenotypes reveal underlying mechanisms and genetic factors contributing to progression and development of four brain disorders.

  (Wen J, Skampardoni I, Tian YE, Yang Z, Cui Y, Erus G, Hwang G, Varol E, Boquet-Pujadas A, Chand GB, Nasrallah IM, Satterthwaite TD, Shou H, Shen L, Toga AW, Zalesky A, Davatzikos C.) Nat Biomed Eng. 2025 Nov;9(11):1920-1937 PMID: 40481237 PMCID: PMC12955822 SCOPUS ID: 2-s2.0-105007361972 06/07/2025

• Disrupted Large-Scale Brain Network Connectivity in Prolonged Grief Disorder: Relationship With Grief-Related Avoidance, Yearning, and Intrusive Thoughts.

  (Blair NP, Hwang G, Ward BD, Claesges SA, Webber AR, Hainsworth KR, Wang Y, Reynolds CF 3rd, Stein EA, Goveas JS.) Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Aug 05 PMID: 40769298 PMCID: PMC12346161 SCOPUS ID: 2-s2.0-105020753594 08/07/2025

• Neuroimaging endophenotypes reveal underlying mechanisms and genetic factors contributing to progression and development of four brain disorders

  (Wen J, Skampardoni I, Tian YE, Yang Z, Cui Y, Erus G, Hwang G, Varol E, Boquet-Pujadas A, Chand GB, Nasrallah IM, Satterthwaite TD, Shou H, Shen L, Toga AW, Zalesky A, Davatzikos C.) Nature Biomedical Engineering. November 2025;9(11):1920-1937 SCOPUS ID: 2-s2.0-105007361972 11/01/2025

• Relationship between MRI brain-age heterogeneity, cognition, genetics and Alzheimer's disease neuropathology.

  (Antoniades M, Srinivasan D, Wen J, Erus G, Abdulkadir A, Mamourian E, Melhem R, Hwang G, Cui Y, Govindarajan ST, Chen AA, Zhou Z, Yang Z, Chen J, Pomponio R, Sotardi S, An Y, Bilgel M, LaMontagne P, Singh A, Benzinger T, Beason-Held L, Marcus DS, Yaffe K, Launer L, Morris JC, Tosun D, Ferrucci L, Bryan RN, Resnick SM, Habes M, Wolk D, Fan Y, Nasrallah IM, Shou H, Davatzikos C.) EBioMedicine. 2024 Nov;109:105399 PMID: 39437659 PMCID: PMC11536027 SCOPUS ID: 2-s2.0-85206914012 10/23/2024

• Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer's disease continuum.

  (Wen J, Yang Z, Nasrallah IM, Cui Y, Erus G, Srinivasan D, Abdulkadir A, Mamourian E, Hwang G, Singh A, Bergman M, Bao J, Varol E, Zhou Z, Boquet-Pujadas A, Chen J, Toga AW, Saykin AJ, Hohman TJ, Thompson PM, Villeneuve S, Gollub R, Sotiras A, Wittfeld K, Grabe HJ, Tosun D, Bilgel M, An Y, Marcus DS, LaMontagne P, Benzinger TL, Heckbert SR, Austin TR, Launer LJ, Espeland M, Masters CL, Maruff P, Fripp J, Johnson SC, Morris JC, Albert MS, Bryan RN, Resnick SM, Ferrucci L, Fan Y, Habes M, Wolk D, Shen L, Shou H, Davatzikos C.) Transl Psychiatry. 2024 Oct 05;14(1):420 PMID: 39368996 PMCID: PMC11455841 SCOPUS ID: 2-s2.0-85205758659 10/06/2024

• Dimensional Neuroimaging Endophenotypes: Neurobiological Representations of Disease Heterogeneity Through Machine Learning.

  (Wen J, Antoniades M, Yang Z, Hwang G, Skampardoni I, Wang R, Davatzikos C.) Biol Psychiatry. 2024 Oct 01;96(7):564-584 PMID: 38718880 PMCID: PMC11374488 SCOPUS ID: 2-s2.0-85195576462 05/09/2024

• The genetic architecture of multimodal human brain age.

  (Wen J, Zhao B, Yang Z, Erus G, Skampardoni I, Mamourian E, Cui Y, Hwang G, Bao J, Boquet-Pujadas A, Zhou Z, Veturi Y, Ritchie MD, Shou H, Thompson PM, Shen L, Toga AW, Davatzikos C.) Nat Commun. 2024 Mar 23;15(1):2604 PMID: 38521789 PMCID: PMC10960798 SCOPUS ID: 2-s2.0-85188443845 03/24/2024