Carol Moreno-Quinn, Ph.d., Assistant Professor, Physiology
Education: Universidad de Murcia, Murcia, Spain, M.D.,Universidad de Murcia, Murcia, Spain, Ph.D., Medical College of Wisconsin, Postdoc
Link to Physiology NIH BIOSKETCH
Complex diseases such as hypertension and renal failure are determined by the interaction of multiple genes with environmental factors. My research interest is focused on identification of the genetic determinants of hypertension and renal disease in rat models of hypertension. Our main strategy is to identify chromosomal regions containing the causative genes through linkage analysis in segregating populations of rats. By the use of consomic strains of rats, we are able to develop congenic strains for our region of interest in only two generations of breeding. Once the region containing the causative gene is small enough, we identify the candidate genes by comparative mapping, DNA sequencing and gene expression.