600 MHz NMR spectrometer. Cryoplatform is visible to the left of the magnet, RF console and workstation to the right.
We operate and maintain one Bruker Avance III 500 and two Bruker Avance 600 NMR spectrometers, each equipped with 1H/13C/15N cryoprobes for enhanced sensitivity in biomolecular applications.
All three instruments are located in a dedicated facility that was specifically designed and outfitted with environmental control, electrical, computer network and other systems appropriate for optimal NMR performance. All NMR instrumentation and computers are protected by UPS. A closed-loop cooling water system supplies the cryoprobe helium compressors. Oxygen level monitors control an auxiliary exhaust system for safety considerations in the event of large-scale cryogen release.
MCW investigators interested in learning more about the potential applications for high-resolution NMR spectroscopy to questions of biomolecular structure and dynamics are encouraged to contact Brian Volkman at bvolkman@mcw.edu