Arshak R. Alexanian, PhD, VMD

Dr. Alexanian is an Associate Professor in the Department of Neurosurgery located at the Neuroscience Research Laboratories at the Zablocki Veterans Affairs Medical Center.  He also has secondary faculty appointment at the rank of Associate Professor of Cell Biology, Neurobiology and Anatomy in the Department of Cell Biology, Neurobiology and Anatomy of the Medical College of Wisconsin.  He specializes in stem cell plasticity and regeneration of the central nervous system.

References:

Alexanian, A.R., Bamburg, J.R.: Neuronal survival activity of S100ββ is enhanced by calcineurin inhibitors and requires activation of NF-kappaβ. FASEB 13(12):1611-1620, 1999.

Alexanian, A.R., Howard, N.O.: Proliferation and regeneration of retrogradely labeled adult rat corticospinal neurons in culture. Experimental Neurology 170(2):277-282, 2001.

Alexanian, A.R., Bamburg, J.R., Hidaka, H., Mornet, D.: Calcium-dependent regulation of interactions of caldesmon with calcium-binding proteins found in growth cones of chick forebrain neurons. Cellular and Molecular Neurobiology 21(5):437-451, 2001.

Alexanian, A.R., Sieber-Blum, M.: Differentiating adult hippocampal stem cells into neural crest derivatives. Neuroscience 118(1):1-5, 2003.

Alexanian, A.R., Kurpad, S.K.: Quiescent neural cells regain multipotent stem cell characteristics influenced by adult neural stem cells in co-culture. Experimental Neurology 119(1):193-197, 2005.

Alexanian, A.R., Crowe, M.J., Kurpad, S.N.: Efficient differentiation and integration of lineage-restricted neural precursors in traumatically injured adult cat spinal cord. Journal of Neuroscience Methods 150:41-46, 2005.

Alexanian, A.R.: Neural stem cells induce bone marrow-derived mesenchymal stem cells to generate neural stem-like cells via juxtacrine and paracrine interactions. Experimental Cell Research 310(2):383-391, 2006.

Macias, M.Y., Syring, M.B., Pizzi, M.A., Crowe, M.J., Alexanian, A.R., Kurpad, S.N.: Pain with no gain: Allodynia following neural stem cell transplantation in spinal cord injury. Experimental Neurology 201:335-48, 2006.

Alexanian, A.R.: Epigenetic modifiers promote efficient generation of neural-like cells from bone marrow-derived mesenchymal cells grown in neural environment. Journal of Cellular Biochemistry 100:362-371, 2007.

Alexanian, A.R., Maiman D.J., Kurpad, S.N., Gennarelli, T.A.: In vitro and in vivo characterization of neurally modified mesenchymal cells induced by epigenetic modifiers and neural stem cells environment. Stem Cells and Development 17: 2008.

How to contact

Alexanian Arshak
Associate Professor
Neuroscience Research Laboratories,
Department of Neurosurgery
VA Medical Center - Research 151
5000 West National Avenue
Milwaukee, Wisconsin 53295
Tel: (414) 384-2000 Ext. 41468
Fax: (414) 384-3493
E-mail: aalexan@mcw.edu