Shouguo Gao, PhD
My current research topics include the following:
(1) Gene networks and inference using Bayesian networks and causality analysis, and applications in elucidating disease pathways.
(2) Topological analysis pathways and protein-protein interactions, and identification of disease related pathways/modules.
(3) Integrative biology for candidate gene discovery for diabetes
For more information, please visit my Personal Homepage.
Publications:
1. Gao Shouguo, Xiang Bingren, An Dengkui, Application of Interactive Rank
Anihilation Factor Analysis in determination of lipid peroxides in Plasma, Computer
and Applied chemistry, 1997,13(13): 85.
2. Gao Shouguo, Xiang Bingren, An Dengkui, Pattern Recognition in determination
of Silicosis for Railway Tunnel Workers, New Trends in Chemometrics, 1997,
Zhangjiajie.
3. Gao Shouguo, Xiang Bingren, An Dengkui, Expert System in Pharmacy, Medicine
and Computer, 1998, (1): 20.
4. Zou Qiaogen, Gao Shouguo, Xiang Bingren, Application and Progress of Expert
System in Chinese Traditional Medicine, Progress in Pharmaceutical Sciences, 1999,
23(2):101.
5. Gao Shouguo, Xiang Bingren, An Dengkui, Prediction of Parameters of Retention
Equation in RP-HPLC with Robust Artificial Neural Networks, Computer and
Applied chemistry, 1999,16(5): 381.
6. Gao Shouguo, Xiang Bingren, An Dengkui, Application of Artificial Neural
Networks in Feature Extraction and Identification of Natural or Artificial Bezoar,
Computer and Applied chemistry, 2000,17(2).
7. Gao Shouguo, Xiang Bingren, Yue JInlian, The Database of High Performance
Liquid Chromatographic Methods in Pharmaceutical Analysis, Progress in
Pharmaceutical Sciences, 1999, 23(5): 287.
8. Li Rui, Gao Shouguo, Xiang Bingren, Prediction of Retention Index with Improved
Artificial Neural Networks, Computer and Applied chemistry, 2000,17(2): 113.
9. Gao Shouguo, Liu Guolin, Xiang Bingren, Establishment of NIR Modeling Center
on Internet, J. NIR Publication. not yet published.
10. Gao Shouguo, Sun Jiancheng, Xiang Bingren, Web Based Database of Separation
Condition for HPLC in Pharmaceutical Analysis, Materia Medica of Central China,
2001, 3(1): 13.
11.Gao Shouguo, Xie Zhaohui, Management Information System for OTC drug Store,
Medicine and Computer, 2000, (1): 31. 12. Gao Shouguo, Li Rui, Xiang Bingren, Application of FAM Networks in Recommendation of Mobile Phase for RP-HPLC, Acta Pharmaceutica Sinica, 2001, 36 (9): 676.
13. Gao Shouguo, Xiang Bingren, Fuzzy Artificial Neural Networks and Application
in QSAR, Computer and Applied chemistry, 2002, 10.
14. Gao Shouguo, Xiang Bingren, Web Based Simulative Test Questions for Certified
Apothecary, Medical Information, 2001, 14(10): 674.
15. Li Rui, Gao Shouguo, Xiang Bingren, Application of Fuzzy Artificial Neural
Networks in the Study of Quantitative Structure Retention Relationship for HPLC, J.
China Pharmaceutical University, 2001,32(8): 264.
16. Shouguo Gao, SIMCA method and application in prediction of protein secondary
structural classes, Computer and Applied chemistry, 2004, 21(5), 714
17. Shouguo Gao, Xuejun Kang, Qian Xu, To establish a networked examination
system for sanitary chemistry using JSP, Journal of southeast university, 2004, 23(1), 22
18. Yizhou Xie, Shouguo Gao, Vicki Magnuson, Soumitra Ghosh and Xujing Wang,
Genomic data mining to narrow down candidate disease genes for Type 1 Diabetes,
ASHG, 2005, Salt Lake City
19. Shouguo Gao, Xujing Wang, TAPPA: A Topological Analysis of Pathway
Association. submitted to Bioinformatics (In Revision).
20. Shuang Jia, Shouguo Gao, Na Lu, Martin Hessner, Xujing Wang, Quality
weighted mean and t-test in microarray analysis lead to improved accuracy in gene
expression measurements and circumvent the missing value problem. submitted to
Journal of Computational Biology. Joint first author
21. Shouguo Gao, Xujing Wang, Bayesian networks based on fuzzy theory and
application in reconstruction of genetic networks in pancreas development and growth,
in preparation.
Book Chapters:
1. Modern Pharmaceutical Analysis, Chinese Medical Technology Press, 2001(Part 6:
Artificial Neural Networks).
2. Jia, S., Gao, S., Hessner, M.J., Wang, X.,: Acquisition of accurate gene expression
information from microarray measurements. In Current Trends in Genetic Research,
World Scientific Publishing. 2006
Software:
Gene Expression Data Analysis Center on Internet (CGI, Perl and SQL Server).
Software Package for Computational Pharmacy (Visual C++).
Hybrid HPLC Expert System in HPLC(Visual C++, SQL Server).
Microarray data analysis pipeline (Java, Perl, mySQL, Tomcat).
TAPPA (Java).