Radiation Oncology

Patient Care Emphases

• General Radiation Oncology
• Head and Neck Cancer
• Lung Cancer

Clinical Practice Locations

• Zablocki VA Medical Center: (414) 384-2000, ext. 42585
• Senator Joseph Andrea Cancer Center, Kenosha, at St. Catherine's Campus of United Healthcare Systems: (262) 577-8206

Research Interests

• Chemoradiation for lung cancer
• Radiation dose strategies in lung cancer
• Chemoradiation for locally advanced head and neck cancer
• Influence of comorbidities on treatment outcomes for lung cancer
• Role of prophylactic cranial irradiation in non-small cell and small cell lung cancer
• Stereotactic radioablation of early stage non-small cell lung cancer
• Management of respiratory motion in treating small conformal fields in early
  stage lung cancer 

Education

• Doctor of Medicine,  Medical College of Wisconsin, Milwaukee, WI (1968).

Training

• Board Certified American Board of Radiology (1973).
• Residency Radiation Oncology, St. Joseph Hospital, Denver, CO (1969-1972).
• Internship Radiation Oncology, St. Joseph Hospital, Denver, CO (1968-1969).

Representative Publications

• Byhardt, R. Toxicities in RTOG Combined Modality Trials for Inoperable Non-Small Cell Lung Cancer.  ONCOLOGY, 10 Suppl (5): 116-120, 1999.
  
• Movsas, B., Scott, C., Sause, W., Byhardt, R., Komaki, R., Cox, J., Johnson, D., Lawton, C., Dar, R., Wasserman, T., Roach, M., Lee, J., Andras, E.  The Benefit of Treatment Intensification is Age and Histology-Dependent in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC):  A Quality-Adjusted Survival Analysis of Radiation Therapy Oncology Group (RTOG) Chemoradiation Studies.  INT J RADIAT ONCOL BIOL PHYS 45 (5): 1143-9, 1999.
  
• Russell, A., Harris, J., Rosenberg, P., Sause, W., Fisher, B., Hoffman, J., Kraybill, W., Byhardt, R. Anal Sphincter Conservation for Patients with Adenocarcinoma of the Distal Rectum: Long-Term Results of RTOG 89-02.  INT J RADIAT ONCOL BIOL PHYS 46 (2): 313-322, 2000.
  
• Sause, W., Kolesar, P., Taylor, S., Johnson, D., Livingston, R., Komaki, R., Emami, E., Curran, W., Byhardt, R., and Fisher, B.: Final Results of Phase III Trial in Regionally Advanced Unresectable Non-Small Cell Lung Cancer:  Radiation Therapy Oncology Group (RTOG) 88-08 and Eastern Cooperative Oncology Group (ECOG) 4588.  CHEST 117 (2): 358-364, 2000.
  
• Trotti, A., Byhardt, R., Stetz, J., Gwede, C., Corn B., Fu, K., Gunderson, L., McCormick, B., Morrisintegral, M., Rich, T., Shipley, W., Curran, W.  Common Toxicity Criteria: Version 2.0. an Improved Reference for Grading the Acute Effects of Cancer Treatment:  Impact on Radiotherapy. INT J RADIAT ONCOL BIOL PHYS 47 (1): 13-47, 2000.
  
• Byhardt, R.   American College of Radiology Expert Panel on Radiation Oncology – Lung Work Group.  American College of ACR Appropriateness Criteria TM 2000.  RADIOLOGY 2000; 215 (Suppl), 1347-1375.
  
• Ko, B., Sause, W., Byhardt, R., Curran, W., Fuller, D., Graham, M., Komaki, R., Weisenburger, T., Kaiser, L., Leibel, S., Brown, R.  Staging of Non-Small Cell Lung Carcinoma.  American College of Radiology.  ACR Appropriateness Criteria.  RADIOLOGY 2000 Jun; 215 Suppl:  1281-94.
  
• Weisenburger, T., Graham, M., Sause W., Byhardt, R., Curran, W., Fuller, D., Ko, B., Komaki, R., Kaiser, L., Leibel, S.  Postoperative Radiotherapy in Non-Small Cell Lung Cancer.  American College of Radiology.  ACR Appropriateness Criteria.  RADIOLOGY 2000 Jun; 215 Suppl: 1295-318.
  
• Komaki, R., Sause, W., Byhardt, R., Curran, W., Fuller, D., Graham, M., Ko, B., Weisenburger, T., Kaiser, L., Leibel, S., Choi, N.  Non-Small Cell Lung Cancer, Nonsurgical, Aggressive Therapy.  American College of Radiology.  ACR Appropriateness Criteria.  RADIOLOGY 2000 Jun; 215 Suppl:  1319-30.
  
• Byhardt, R., Sause, W., Curran, W., Fuller, D., Graham, M., Ko, B., Komaki, R., Weisenburger, T., Kaiser, L., Leibel, S., Choi, N.  Neoadjuvant Therapy for Marginally Resectable (Clinical N2), Non-Small Cell Lung Cancer.  American College of Radiology.  ACR Appropriateness Criteria.  RADIOLOGY 2000 Jun; 215 Suppl: 1331-45.
  
• Graham, M., Byhardt, R., Sause, W., Curran, W., Fuller, D., Ko, B., Komaki, R., Weisenburger, T., Kaiser, L., Leibel, S.  Non-aggressive, Non-surgical Treatment of Inoperable Non-Small Cell Lung Cancer (NSCLC).  American College of Radiology.  ACR Appropriateness Criteria.  RADIOLOGY 2000 Jun; 215 Suppl; 1347-62.
  
• Sause, W., Byhardt, W., Curran, W., Fuller, D., Graham, M., Ko, B., Komaki, R., Weisenburger, T., Kaiser, L., Leibel, S., Brown, R.  Follow-up of Non-Small Cell Lung Cancer.  American College of Radiology.  ACR Appropriateness Criteria.  RADIOLOGY 2000 Jun; 215 Suppl:  1363-72.
  
• Werner-Wasik, M., Scott, C., Cox, J., Sause, W., Byhardt, W., Asbell, S., Russell, A., Komaki, R., Lee, J.  Recursive Partitioning Analysis of 1999 Radiation Therapy Oncology Group (RTOG) Patients With Locally Advanced Non-Small Cell Lung Cancer (LA-NSCLC):  Identification of Five Groups With Different Survival.  INT J RADIAT ONCOL BIOL PHYS, 48 (5): 1475-1482. 2000.
  
• Byhardt, R., Scott, C.  A Palliative Accelerated Irradiation Regimen for Advanced Non-Small Cell Lung Cancer vs, Conventionally Fractionated 60 Gy:  Results of a Randomized Equivalence Study:  Regarding Nestle et al.  INT J RADIAT ONCOL BIOL PHYS.  2000; 48:95-103.
  
• Hammond, M., Ang, K., Byhardt, R., Campbell, B., Chapman, J., Eisenberg, B., Greven, K., Harris, J., Hoffman, J., Lange, C., McCormick, B., Mehta, M., Sandler, H., Trotti, A., Willet, C., Wolfson, A., Furness, A., Jensen, T., Grignon, D., Okunieff, P.  Radiation Therapy Oncology Group.  Research  Plan 2002-2006.  Tumor Utilization Committee.  INT J RADIAT ONCOL BIOL PHYS. 2001; 51(3 Suppl 2): 103-9.
  
• Komaki, R., Chasen, M., Travis, W., Putnam, J., Fossella, F., Byhardt, R., Ro, J.  Oncodiagnosis Panel:  1999.  Cancer of the Lung:  Oncodiagnosis.  RADIOGRAPHICS. 2001 Nov-Dec; 21 (6); 1573-96.
  
• Tester, W., Caplan, R., Heaney, J., Venner, P., Whittington, R., Byhardt, R., True, L., and Shipley, W.:  Neoadjuvant Combined Modality Program With Selective Organ Preservation for Invasive Bladder Cancer:  Results of Radiation Therapy Oncology Group Phase II Trial 88-02.  J Clin Oncol:  Classic Papers & Current Comments, 6 (2): 379-387, 2001.
  
• Firat, S., Bousamra, M., Gore, E., Byhardt, R.  Comorbidity and KPS are Independent Prognostic Factors in Stage I Non-Small Cell Lung Cancer.  INT J RADIAT ONCOL BIOL PHYS. 2002 Mar 15;52 (4): 1047-57.
  
• Firat, S., Byhardt, R., Gore, E.  Comorbidity and Karnofksy  Performance Score are Independent Prognostic Factors in Stage III Non-Small Cell Lung Cancer:  an Institutional Analysis of Patients Treated on Four RTOG Studies.  INT J RADIAT ONCOL BIOL PHYS.  2002 Oct 1;54 (2): 357.
  
• Johnston, D., Byhardt, R., Ettinger, D., Scott, C.  Phase III Study Comparing Chemotherapy and Radiotherapy with Preoperative Chemotherapy and Surgical Resection in Patients with Non-Small Cell Lung Cancer with Spread to Mediastinal Lymph Nodes (N2); Final Report of RTOG 89-01.  INT J RADIAT ONCOL BIOL PHYS. 2002 Oct 1;54 (2): 365.