Radiation Oncology

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X. Allen Li, PhD

                             

 X. Allen Li, PhD
Chief of Physics and Professor

Department of Radiation Oncology
8701 Watertown Plank Road
Milwaukee, WI 53226
(414) 805-4362 phone
(414) 805-4354 fax
ali@mcw.edu

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   Additional Information (curriculum vitae)
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Research Interests

  • Biological modeling for radiation treatment planning
  • Anatomical/biological/functional imaging guided radiotherapy planning and delivery
  • Monte Carlo application to radiotherapy dosimetry

Education

  • PhD, Electron Paramagnetic Resonance  Department of Physics, Concordia University, Montreal, Quebec, Canada (1989-1992).
  • MS, Electron Optics and Electron Microscopy Department of Physics, Yunnan University, Kunming, China (1983-1986).
  • BS, Electron Physics Department of Physics, Yunnan University, Kunming, China (1979-1983).

Training

  • Clinical Physics Resident, Ottawa Regional Cancer Centre, Ottawa, Canada (1993-1994).
  • Postdoctor, Ionizing Radiation, National Research Council Canada, Ottawa, Canada (1992-1993).

Recent Publications

  • LI, X.A., O'Neill, M., Suntharalingam, M.: Improving patient specific dosimetry for intravascular brachytherapy. J Brachytherapy 4, 291-297, 2005.

  • Wang, J.Z., LI, X.A.: Impact of Tumor Proliferation on Radiotherapy Treatment Planning, Int J Radiat Oncol Biol Phys. 61, 220-227, 2005.

  • Guerrero, G., LI, X.A., Ma, L., Linder, J., DeYoung, C., Erickson, B.: Simultaneous integrated IMRT boost for locally advanced gynecological cancers: radiobiological and dosimetric considerations.  Int J Radiat Oncol Biol Phys. 62, 933-939, 2005.

  • LI, X.A., Wang, J.Z., Jursinic, P., Lawton, C., Wang, D.: Dosimetric advantages of IMRT simultaneous integrated boost for high-risk prostate cancer.  Int J Radiat Oncol Biol Phys. 61, 1251-1257, 2005.

  • Cheng, C-W, Mitra, R., LI, X.A., Das, I.J.: Dose perturbations due to contrast medium and air in MammoSite treatment: An experimental and Monte Carlo study: Med. Phys. 32, 2279-2287, 2005.

  • Naqvi, S.A., D'Souza, W.D., Earl, M.A., Ye, S.J., Shih, R., LI, X.A. : Using a photon phase-space source for convolution/superposition dose calculations in radiation therapy. Phys Med Biol. 50, 4111-24, 2005. 

  • Qi, X.R., Schultz, C.J., LI, X.A.: An estimation of radiobiological parameters from clinical outcomes for radiation treatment planning of brain tumors. Int J Radiat Oncol Biol Phys. 64, 1570-1580, 2006.

  • Wang, J. Z., LI, X.A., Mayr, N.A.: Dose escalation to combat hypoxia in prostate cancer, a radiobiological analysis of clinical data. Br. J. Radiol.  79, 905-911, 2006.

  • Wang, D., Schultz, C.J., Jursinic, P.A., Bialkowski, M., Zhu, R., Brown, W.D., Rand, S.D., Campbell, B.H., Wong, S., LI, X.A., Wilson, J.F.: FDG-PET/CT guided intensity modulated radiation treatment for head and neck carcinoma. Int J Radiat Oncol Biol Phys. 65, 143-151, 2006.

  • LI, X.A., Stepaniak, C., Gore, E.: Technical and dosimetric aspects of respiratory gating using a pressure-sensor motion tracking system. Med. Phys. 33, 145-154, 2006.

  • Guerrero, M., LI, X.A.:  Halftime for repair of sublethal damage in normal bladder and rectum: an analysis of clinical data from cervix brachytherapy.  Phys. Med. Biol. 51, 4063-4071, 2006.

  • LI, X.A., Hendee R.W.:  Radiation Oncology physicists will need to better understand medical imaging. J. Am Coll Radiol., 4, 40-44, 2007.

  • Qi, X.S., Schultz, C. J., LI, X.A.: Possible fractionation regimens for treatment of large size arteriovenous malformation using IG-IMRT. Int J Radiat Oncol Biol Phys. Submitted, 2006.

  • LI, X.A., Wang, J.Z., Stewart, R.J., DiBiase, S.J., Wang, D., Lawton, C.: Designing equivalent treatment regimens for prostate radiotherapy using equivalent uniform dose. Br. J. Radiol. In press, 2007.

  • LI, X.A., Qi, X.S., Pitterle M., Kalakota K., Mueller, K., Jursinic, P.A., Erickson, B.A., Wang, D., Schultz, C.J.,   Firat, S.Y., Wilson, J.F.:  Inter-fractional variations in patient setup and anatomic change assessed by daily CT from helical tomotherapy.  Int J Radiat Oncol Biol Phys.  68, 581-591, 2007.

  • Chen, G.P., Ahunbay, E., Schultz, C.J., LI, X.A.: Development of an inverse optimization package to plan non-uniform dose distributions based on spatially inhomogeneous radiosensitivity extracted from biological images, Med. Phys. 34, 1198-1405, 2007.

  • Hsiao, Y., Stewart, R.D., LI, X.A.: A Monte-Carlo derived dual-source model for helical Tomotherapy treatment planning. Phys. Med. Biol. Submitted, 2007.

  • Bovi, J., Qi, S.X., White, J., LI, X.A.: Comparison of three partial breast irradiation techniques: treatment effectiveness based upon biological models. Radiother. & Oncol. In press  2007.

  • Ahunbay, E., Chen, G.P., Jursinic, P., White, J., Thatcher, S., Albano, K., LI, X.A.,:  Direct aperture optimization based IMRT for whole breast irradiation.  Int J Radiat Oncol Biol Phys. 67, 1248-1258, 2007.

  • Zhu, T.C., Ahnesjö, A., Lam, K.L., LI, X.A., Ma, C.M., Palta, J.R., Sharpe, M.B., Thomadsen, B., Tailor, R.C.:  Report of AAPM Radiation Therapy Committee Task Group 74: in-air output ratio for megavoltage photon beams. Med. Phys. Submitted, 2007.

  • Yang, Q., Feng, Y., Qi, X.S., Schultz, C.J., LI, X.A., Wilson, J.F., Wang, D.: Synergistic effect of 15-lipoxygenase 2 and radiation on carcinoma cells of head and neck. Int J Radiat Oncol Biol Phys, Submitted, 2007.

  • Morrow, N.V., Stepaniak, C., White, J., Wilson, J.F., LI, X.A.:  Inter- and intra-fractional uncertainties for prone breast irradiation. Int J Radiat Oncol Biol Phys, In press, 2007.

  • Ahunbay, E., LI, X.A.: Investigation of the reliability, accuracy and efficiency of gated IMRT delivery with a commercial linear accelerator. Med. Phys., 34, 2928-2938, 2007.

  • Cohen, E.P., Fish, B.L., Sharma, M., LI, X.A., Moulder, J.E.:  Angiotensin II blockade in radiation nephropathy: the role of the AT2 receptor.  Experi Biol. Med. In press, 2007.

  • Das, I.J.,Cheng, C.W.,Ahnesjö, A.Gibbons, J., LI, X.A., Lowenstein, J., Mitra, R.K., Simon, W.E., Watts, R.J., Zhu, T.C.:  Report of AAPM Radiation Therapy Committee Task Group 106: Accelerator beam data commissioning equipment and procedures. Med. Phys. Submitted, 2007.

  • Qi, X.S., Yang, Q., LI, X.A.,Feng, Y.,Wang, D.:  Radiobiology consideration in optimazation of radiation treatment outcome for head and neck carcinoma.  Int J Radiat Oncol Biol Phys, Submitted, 2007.

  • Kainz K., Stepaniak C, Gore E., Li X.A.: Variation of total lung DVH during Respiration. Int J Radiat Oncol Biol Phys, submitted, 2007.

  • Tai A, Erickson B, Khater K, Li X.A.: Estimate of radiobiological parameters from clinical data for biologically based treatment planning for liver irradiation. Int J Radiat Oncol Biol Phys, submitted, 2007.

  • Kainz K, White J, Herman J, England M, Li XA.: Exploring helical tomotherapy for simultaneously irradiating breast and regional nodes in prone position. Int J Radiat Oncol Biol Phys, submitted. 2007.

  • Qi X.S., White J, Sood A, Bauer A, Tao R, Willson J.F., Li X.A.: Respiratory Organ Motion And Dosimetric Impacts On Breast And Nodal Irradiation. Int J Radiat Oncol Biol Phys, submitted. 2007.

  • Semenenko V.A, Li X.A.: Lyman NTCP Model Parameters for Radiation Pneumonitis and Xerostomia Based on Combined Analysis of Published Clinical Data. Int J Radiat Oncol Biol Phys, submitted. 2007.

  • Peng C, Kainz K, Lawton C, Li X.A.: A comparison of daily megavoltage ct and ultrasound image guided radiation therapy for prostate cancer. Int J Radiat Oncol Biol Phys, submitted, 2007.

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