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     Active Protocols


    Protocol #

    Title

    PI

    Department

    442

    Hepatitis C in Hemophilia

    Gill, J.

    Pediatrics/Hematology

    501

    Effects of Cigarette Smoking and Nicotine on Regional Cerebral Activity as Measured by Functional MRI

    Risinger, R.

    Psychiatry

    503

    Immunologic Mechanism of Inhibitor Antibody Function Formation in Hemophilia and Von Willebrand Disease

    Gill, J.

    Pediatrics/Hematology

    509

    Red Blood Cell Adherence to Vascular Endothelium in Sickle Cell Disease

    Hillery, C.

    Pediatrics/Hematology

    531

    Upper Esophageal Sphincter Opening and Transsphincter Flow

    Shaker, R.

    Medicine/Gastroenterology

    536

    Familial Determinants of Hypertension

    Kotchen, T.

    Medicine/Administration

    537

    Genes of Hypertension in African Americans:  Phase II

    Kotchen, T.

    Medicine/Administration

    553

    Effects of Intravenous cocaine on Regional Cerebral Activity as Measured by Functional MRI

    Risinger, R.

    Psychiatry

    572

    Effect of Delta-9 Tetrahydrocannabinol on Regional Cerebral Activity as Measured by Functional MRI

    Bloom, A.

    Pharmacology

    576

    Clinical Centers for the Clinical Trial and Observational Study of the Women's Health Initiative - East

    Kotchen, J.

    HPI/Epidemiology

    582

    Functional MRI of Human Brain Language Systems

    Binder, J.

    Neurology

    598

    Effects of Nicotine Withdrawal on Regional Cerebral Activity as Measured by Functional MRI

    Risinger, R.

    Psychiatry

    600

    Neurobiology of Cocaine Abuse Detected by Functional MRI

    Li, S.

    Biophysics

    622

    Universal Data and Serum Specimen Collection for Hemophilia and Other Bleeding Disorders

    Gill, J.

    Pediatrics/Hematology

    623

    Genetics of Obesity Related Subphenotypes

    Kissebah, A.

    Medicine/Endocrine

    632

    Functional MRI of Cognitive Processes

    Rao, S.

    Neurology

    635

    Stress Reduction and Cardiovascular Morbidity and Mortality in African Americans

    Kotchen, J.

    Medicine/Administration

    643

    Genetics of Inhibitor Development in Hemophilia

    Gill, J.

    Pediatrics/Hematology

    650

    Wisconsin Pediatric Cardiac Registry:  Consent for Involvement and Participation in Environment and Genetic Studies

    Pelech, A.

    Pediatrics/Cardiology

    669

    Presurgical Applications of Functional MRI in Epilepsy

    Binder, J.

    Neurology

    685

    Functional Mapping of Human Visual Cortex

    DeYoe, E.

    Radiology Research

    686

    Intravenous Ethanol Infusion Study of Airway Protective Reflexes

    Shaker, R.

    Medicine/Gastroenterology

    691

    Definition of Chronic Lung Disease in Cystic Fibrosis through  High Resolution Computed tomography as Related to Diagnosis through Neonatal Screening

    Bandla, H.

    Pediatrics/Pulmonary

    697

    Facilitating Discovery through a Human Prostate Tissues Resource

    Becker, C.

    Pathology

    698

    Comparison of the Unsedated Transnasal Upper GI Endoscopy with Scintigraphy for the Evaluation of Gastric Emptying

    Shaker, R.

    Medicine/Gastroenterology

    702

    Ischemic Heart Disease in Blacks:  Project 2: Genetic Basis of Coronary Artery Collateralization

    Broeckel, U.

    Medicine/Cardiovascular

    704

    Pathophysiological Mechanisms in Type I vWD

    Montgomery, R.

    Pediatrics/Hematology

    705

    Molecular Variants Causing von Willebrand Disease

    Montgomery, R.

    Pediatrics/Hematology

    709

    Selenium and Vitamin E Cancer Prevention Trial (SELECT)

    Donnell, R.

    Urology

    711

    Esophageal Motor Function in Health and Disease

    Shaker, R.

    Medicine/Gastroenterology

    712

    CYP2E1 and ADH in Human TRI Teratogenicity

    McCarver, D

    Pediatrics/Neonatology

    716

    Genetics of Autoimmunity in Type 1 Diabetes

    Ghosh, S.

    Pediatrics/Endocrinology

    719

    The Second Multicenter Hemophilia Cohort Study (MHCS-II)

    Gill, J.

    Pediatrics/Hematology

    721

    Does Exercise-Induced Hypertension in Weight Lifting Reduce Vascular Reactivity?

    Gutterman, D.

    Medicine/Cardiovascular

    722

    Neural Substrates of Human Cocaine Self-administration

    Risinger, R.

    Psychiatry

    724

    Genetics of Pediatric-Onset Systemic Lupus Erythematosus

    Nocton, J.

    Pediatrics/Rheumatology

    725

    The Role of Executive Functions in Cocaine Abuse

    Garavan, H.

    Psychiatry

    738

    Neuroimaging Tools for Assessing Visual System Pathology

    DeYoe, E.

    Radiology Research

    739

    Cerebral Cortical Representation of Gut Sensory Motor Function

    Shaker, R.

    Medicine/Gastroenterology

    740

    Functional Neuroanatomy of Human Fear Conditioning

    Rao, S.

    Neurology

    741

    Neurocognitive Functioning and Brain Activation in Acute MTBI: A Neuropsychological and Functional MRI Study

    Hammeke, T.

    Neurology

    746

    Serum Neuron Specific Enolase and S 100 B Rapid ELISA for Identification of Parenchymal Brain Injury Associated with Non-Accidental Head Trauma in Young Children

    Hennes, H.

    Pediatrics/Emergency Med.

    747

    fMRI of the Person Identity Network: Aging and APOE

    Rao, S.

    Neurology

    748

    Molecular Pathogenesis of P. Aeruginosa in CF

    Barbieri, J

    Microbiology

    749

    Functional MRI Alterations During Cerebral Vasospasm

    Sinson, G.

    Neurosurgery

    750

    Genotype/Phenotype Correlation in New Onset Pediatric IBD Patients

    Kugathasan, S.

    Pediatrics/Gastroenterology

    751

    Alzheimer's Disease by Functional MR Imaging

    Li, S.

    Biophysics

    752

    Determinants of Early Pancreatic Injury in Cystic Fibrosis

    Gershan, W.

    Pediatrics/Pulmonary

    753

    Multi-Mutational Analysis for Cystic Fibrosis (CF) Mutant Alleles

    Gershan, W.

    Pediatrics/Pulmonary

    756

    Female Athlete Triad Characteristics in High School Athletes

    Hoch, A.

    Orthopaedic

    757

    Functional MRI alterations after traumatic brain injury

    Sinson, G.

    Neurosurgery

    762

    MRI Contrast Agent Methods to Assess Tumor Angiogenesis

    Schmainda, K.

    Radiology Research

    763

    MRI  Upper Airway Evaluation with Waking Controlled Ventilation

    Woodson, BT

    Otolaryngology

    764

    Effects of intravenous dobutamine and cocaine on regional cerebral activity as measured by functional MRI

    Rainey, C.

    Psychiatry

    769

    Differential Cerebral Response to Psychometric Testing in Patients with Minimal Hepatic Encephalopathy as Compared to Health Individuals on Functional MRI Scanning

    Saeian, K

    Medicine/Gastroenterology

    770

    Neurophysiological Basis of Speech Perception

    Liebenthal, E.

    Neurology

    773

    Functional Neuroimaging and Cognition in Pre-symptomatic Huntington's Disease

    Rao, S.

    Neurology

    777

    Milwaukee Healthy Homes Demonstration Project:  A Randomized Controlled Study to Improve Qualityof Life and Reduce Home Environment Triggers for Children with Asthma

    Meurer, J

    Pediatrics/Community

    778

    Biofeedback Pretreatment Baseline for Pediatric Headache

    Franklin, S

    Pediatrics/Child Dev.

    779

    Genetic Modifiers of Cystic Fibrosis:Sibling Study

    Gershan, W.

    Pediatrics/Pulmonary

    780

    Managing Diabetes: Use of a Digital Intercom System

    Burns, E.

    Medicine/Geriatrics

    781

    An Open Trial of Ziprasidone, Early in the Course of Pediatric Psychotic Illness, Phase IV

    Scheffer, R.

    Pediatrics/Psychiatry

    783

    Cirrhosis, Liver Fibrosis and Peripheral Vascular Reactivity

    Saeian, K

    Medicine/Gastroenterology

    784

    Focal Segmental Glomerulosclerosis Clinical Trial

    Pan, C.

    Pediatrics/Nephrology

    785

    A Preclinical Risk Marker for AlzheimerÕs Disease by FMRI

    Antuono, P.

    Neurology

    786

    FMRI of Phonetic Perception in Children

    Conant, L.

    Neurology

    787

    A Double-Blind, Crossover Trial of Aricept in Memory-impaired Patients with Multiple Sclerosis: A Phase IV Demonstration of Functional MRI (fMRI) as a Surrogate Marker of Brain Activity Associated with Improvement in Memory Functioning

    Jaradeh, S.

    Neurology

    788

    fMRI Evaluation of Parkinson's Disease

    Rao, S.

    Neurology

    789

    The Effect of Amiodarone on Coronary Blood Flow in Patients Presenting with an Acute Coronary Syndrome Undergoing Percutaneous Coronary Interventions

    Marks, D.

    Medicine/Cardiovascular

    790

    Epidemiology and Genetics of Female Breast Cancer

    Broeckel, U.

    Medicine/Cardiovascular

    791

    Validity of Serum Markers to Assess the Effect of CPAP Treatment in Patients with Obstructive sleep Apnea Hypopnea Syndrome

    Franco, R.

    Medicine/Pulmonary

    792

    Genetic Studies of Human Development Disorders

    Semina, E.

    Pediatrics/Genetics

    793

    The Effects of a Low Fat Diet Compared to a Low Carbohydrate Diet on Endothelial Function

    Gutterman, D.

    Medicine/Cardiovascular

    794

    Is Vascular Reactivity Reduced During Exacerbations of Inflammatory Bowel Disease?

    Gutterman, D.

    Medicine/Cardiovascular

    795

    Evaluation of the use of contrast-enhanced cardiac magnetic resonance imaging in the diagnosis of cardiac amyloidosis (pilot study)

    Migrino, R.

    Medicine/Cardiovascular

    796

    Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression Trial - EXTended criteria donors (BENEFIT-EXT) Clinical Protocol IM103027

    Hariharan, S.

    Medicine/Nephrology

    797

    The Assessment of Knowledge in Patients with End-State Renal Disease (ESRD) Treated with Hemodialysis

    Kleinman, J.

    Medicine/Nephrology

    799

    Does Endurance Exercise Protect Against Exercise Induced Endothelial Dysfunction?

    Gutterman, D.

    Medicine/Cardiovascular

    800

    Folic Acid and L-Arginine Supplementation in Amenorrheic and Eumenorrheic Women Runners

    Hoch, A.

    Orthopaedic

    801

    Chronic Kidney Disease in Children (CkiD)

    Pan, C.

    Pediatrics/Nephrology

    802

    Role of Leukotriene B4 Metabolism in Severe Asthma

    Jacobs, E.

    Medicine/Pulmonary

    803

    Establishing a Link Between Numeracy and Health

    Schapira, M.

    Medicine/Internal

    804

    Effects of Cigarette Smoking and Smoking Cessation on Brain Activity

    Bloom, A.

    Pharmacology

    805

    Silent Infarct Transfusion Trial (SITT)

    Panepinto, J.

    Pediatrics/Hematology

    806

    Esophageal Motor Function in Health and Disease: Sensory Implications

    Shaker, R.

    Medicine/Gastroenterology

    807

    A Family Study to Assess Genetic and Environmental Risk Factors in Inflammatory Bowel Disease

    Kugathasan, S.

    Pediatrics/Gastroenterology

    808

    Functional MRI to Document Recovery Followoing Pediatric Traumatic Brain Injury: A Pilot Study

    Tieves, K.

    Pediatrics/Critical Care

    809

    Simultaneous fMRI/ERP of Auditory Change Detection

    Liebenthal, E.

    Neurology

    810

    Effect of Yogurt Supplementation on Liver Inflammatory Markers and Psychometric Test Performance in Cirrhotic Patients with Minimal Hepatic Encephalopathy

    Bajaj, J.

    Medicine/Gastroenterology

    811

    Assessment of the Benefits, Risks, and Costs of Neonatal Screening for Cystic Fibrosis

    Gershan, W.

    Pediatrics/Pulmonary

    814

    Novel Therapies for Resistant Focal Segmental Glomerulosclerosis

    Greenbaum, L.

    Pediatrics/Nephrology

    815

    Determination of the optimal prophylactic platelet dose strategy to prevent bleeding in thrombocytopenic patients

    Punzalan, R.

    Pediatrics/Hematology

    816

    Functional Magnetic Resonance Imaging of the Anterior Temporal Lobe

    Binder, J.

    Neurology

    817

    Effects of Hormone Therapy on Subclinical Neurological Pathology

    Kotchen, J.

    HPI/Epidemiology

    818

    Health-Related Quality of Life in Children with Sickle Cell Disease: A Comparison of the Child Health Questionnaire and the PedsQL, Assessment of Parent's Well Being, and Determination of Family Factors Impacting a Child's Health-Related Quality of Life

    Panepinto, J.

    Pediatrics/Hematology

    819

    A Multicenter, Randomized, Controlled Trial of Fresh Frozen Plasma or No Therapy Prior to Invasive Hepatobiliary Procedures  SHIP: Study of Hemostasis and Invasive Procedures

    Hohenwalter, E.

    Radiology

    820

    Neurobiological Predictors of Responses to Medications in Pediatric Bipolar Disorder

    Scheffer, R.

    Psychiatry

    821

    Role of Phosphatidylserine in Immune Evasion by Neuroblastoma

    Shilyansky, J.

    Pediatric Surgery

    822

    Genetic Analysis of Aortic Valve Disease

    Pelech, A.

    Pediatrics/Cardiology

    823

    Arginine Supplementation in Sickle Cell Anemia: Physiological and Prophylactic Effects

    Scott, JP

    Pediatrics/Hematology

    825

    Stroke with transfusions changing to hydroxyurea (SWiTCH): a phase III randomized clinical trial to compare standard therapy (erythrocyte transfusions with iron chelation) with alternative therapy (hydroxyurea with phlebotomy) for the prevention of second

    Scott, JP

    Pediatrics/Hematology

    827

    Controlled Trial of Valproate and Risperidone in Young Children with Bipolar Disorders

    Scheffer, R.

    Psychiatry

    828

    Indication of Attention and Executive Impairment in Early Neurological Injury

    Heffelfinger, A.

    Neurology

    2002

    Prevalence of Low von Willebrand Factor in Women with Menorrhagia

    Gill, J.

    Pediatrics/Hematology

    2009

    Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)

    Cronin, M.

    Medicine/Rheumatology

    2019

    Wisconsin Registry for Alzheimer's Prevention (WRAP-Milwaukee)

    Kerwin, D.

    Medicine/Geriatrics

    2056

    Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosupression Trial (BENEFIT) Clinical Protocol: IM1O3008

    Bresnahan, B.

    Medicine/Nephrology

    2082

    Segmental myocardial strain measurement using tissue tracking 2D echocardiography and cardiac magnetic imaging in the assessment of myocardial viability

    Migrino, R.

    Medicine/Cardiovascular

    2098

    Learning Novel Auditory Categories

    Liebenthal, E.

    Neurology

    2205

    fMRI Database and Registry

    Rao, S.

    Neurology

    2225

    Functional MRI of Recovery in Fluent Aphasia

    Medler, D.

    Neurology

    2282

    Comparison of 1 H MR Spectroscopy: 1.5T vs 3T

    Prost, R.

    Radiology Research

    2285

    Assessment of Carotid Plaque Regression with High Dose Atorvastatin Using High Field Magnetic Resonance Imaging (Pilot Study)

    Migrino, R.

    Medicine/Cardiovascular

    2321

    Echocardiographic Discrimination of Transient Apical Cardiomyopathy (TAC), Anterior Wall Myocardial Infarction, and Normal LV Systolic Function

    Woods, T.

    Medicine/Cardiovascular

    2341

    Evaluation of Driving Skills in Cirrhotic Patients Using a Driving Simulator

    Bajaj, J.

    Medicine/Gastroenterology

    2346

    Does Exercise Exert a Protective Effect Against Acute Hypertension-induced Endothelial dysfunction in Microcirculation?

    Gutterman, D.

    Medicine/Cardiovascular

    2364

    Women's Intervention Nutrition Extension Study (WINS)

    Schectman, G.

    Medicine/Internal

    2368

    A Phase I, Randomized, Double-blind, Placebo controlled, Dose-escalation Study to Evaluate Safety and Tolerability of a Single IV Dose of MEDI-545, a Fully Human Monoclonal Antibody Directed Against Interferon Alpha Subtypes, in Patients w/mild SLE

    Cronin, M.

    Medicine/Rheumatology

    2416

    Effectiveness of Tailored Intervention for Osteoporosis Prevention

    Csuka, M.

    Medicine/Rheumatology

    2449

    Differentiating between causes of dysphagia: role of biomechanical and anatomic esophageal wall characteristics determined by intraluminal esophageal ultrasonography

    Tipnis, N.

    Pediatrics/Gastroenterology

    2485

    Effect of Diabetes Mellitus on Cholesterol Absorption, Synthesis and Statin Efficacy

    Patel, S.

    Medicine/Endocrine

    2565

    Effect of Exercise against Vascular Endothelial Dysfunction during Oral Glucose and High Fat Load

    Gutterman, D.

    Medicine/Cardiovascular

    2569

    Assessment of Cognition among Breast Cancer Survivors

    Nattinger, A.

    Medicine/Internal