Emergency Medicine

Emergency Medicine

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What kind of research will potentially be conducted?

Relevant clinical trials conducted by ROC may include, but are not limited to, the following scientific needs and considerations:

 

  • Evaluation of pharmacologic interventions to address a three-phase (electrical, circulatory, and metabolic) approach to resuscitation from cardiac arrest.
  • Evaluation of optimal strategies of fluid resuscitation including permissive hypotension, timing of initiation of infusion, and use of alternative fluids particularly after traumatic injury.
  • ROC Hypertonic Saline Trial
  • Use of immune modulators in improving clinical outcomes by altering systemic and/or regional inflammatory responses accompanying shock or shock-like states.
  • Evaluation of novel hemorrhage control strategies.
  • Use of cerebral protection and neurologic preservation, with an emphasis on functional outcome.
  • Evaluation of metabolically directed therapies, such as a rapid induction of moderate systemic hypothermia and other novel methods to reduce metabolic demands in the immediate post-arrest/resuscitation interval.
  • Evaluation of alternative CPR approaches including device-assisted CPR including defibrillators.
  • Evaluation of optimal ventilation and oxygen delivery systems and methods for airway protection.
  • ROC PRIMED Trial
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