Shailendra Patel, MD, PhD

Shailendra Patel, MD, PhD

Professor of Medicine
Director of Clinical, Research and Education Efforts
Division of Endocrinology, Department of Medicine

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Dr. Shailesh B. Patel is a Professor of Medicine at the Medical College of Wisconsin, Division of Endocrinology, Metabolism and Clinical Nutrition, Milwaukee, WI. Dr. Patel attended Oxford University, UK for his undergraduate (BA Physiological Sciences), medical (BM, ChB) and post-graduate training (DPhil). He completed internship in Medicine at Torbay General Hospital, Torquay, England, and in Neurosurgery at Western General Hospital, Edinburgh, Scotland, a residency at the Freeman and Newcastle General Hospitals, England, postgraduate training in Metabolic and Molecular Medicine (Endocrinology) at Northwick Park Hospital, London, as well as completing a fellowship in Endocrinology at UT Southwestern Medical School, Dallas, TX. Dr. Patel is board certified in Internal Medicine and Endocrinology. He is an elected fellow of both the Royal College of Medicine and of the American Society for Clinical Investigation. He is a member of the American Diabetes Association, the Endocrine Society and the American Society of Human Genetics. Dr. Patel has authored more than 50 scientific papers in peer-reviewed journals in topics ranging from genetics of lipid disorders and obesity, to lipoprotein research and molecular biology. His current research involves the role of cholesterol in embryonic development, the role of ABCG5 and ABCG8 in cholesterol and xenosterol protection in humans and animal models and the study of rare sterol genetic disorders.

Dr. Patel was elected recently as Fellow of the National Lipid Association in 2011 and Fellow of the American College of Physicians in 2013. He was also elected as President of the American Diabetes Association-Wisconsin Chapter for 2013.

Care Emphasis

  • Cholesterol/Lipid Disorders
  • Diabetes Type 1 & 2
  • Insulin Pump Management
  • Endocrine Disorders
  • Transgender Endocrinology
  • Thyroid Disorders
  • Genetic Disorders of Metabolism
  • Metabolic Disorders
  • Cardiovascular Risk Factor Management

Joined Medical College of Wisconsin

  • 2005


  • Doctor of Medicine - Oxford University - , United Kingdom (1985)
  • Fellowship in Metabolic and Molecular Medicine - Royal College of Physicians - London, United Kingdom (1992-1993)
  • Fellowship in Endocrinology - University of Texas Southwestern Medical School - Dallas (1995-1997)
  • Internship in House Surgeon-Department of Neurosurgery - Western General Hospital - Edinburgh, Scotland (1985-1986)
  • Internship in Internal Medicine-House Physician - Torbay Hospital - Torquay, UK (1986)
  • Residency in Internal Medicine - Freeman and Newcastle General Hospitals - Newcastle upon Tyne, UK (1986-1988)
  • Fellowship in Endocrinology and Internal Medicine - Northwick Park Hospital - Harrow, En, UK (1989-1992)

Board Certifications

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism


  • English
  • Hindi
  • Gujarati

Investigative Interests

  • Genetics
  • Physiology and Pathophysiology of Cholesterol Disorders
  • Embryonic Development

The major interests are focused around rare human disorders of sterol metabolism and how these allow us greater insight into normal processes. My laboratory is currently studying the pathophysiology of the Smith-Lemli-Opitz syndrome (role of cholesterol in embryonic development) and Sitosterolemia (how our bodies regulate dietary sterols, including cholesterol). This research is funded by the National Institutes of Health. The current work relates to genetic investigations in humans, as well as developing and studying animal models of these rare diseases to better understand the pathophysiology.

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