Gastroenterology & Hepatology

Daniel Stein, MD
Assistant Professor
Doctor of Medicine (MD)
2003: Creighton University School of Medicine
Residency
2003-2006: University of Arizona, Tucson, AZ
Visiting Inflammatory Bowel Disease Fellowship
2009: Gastroenterology, University of Chicago, Chicago, IL
Fellowship
2007-2010: Gastroenterology & Hepatology, Medical College of Wisconsin, Milwaukee, WI 

 Clinical Interests & Patient Appointments

PUBLICATIONS (To view complete Curriculum Vitae, click here)

Manuscripts

1. Stein DJ, Ashwin N. Ananthakrishnan, Mazen Issa, John B. Williams, Dawn B. Beaulieu, Yelena Zadvornova, Anita Ward, Kathryn Lemke, Josh F. Knox, Sue Skaros, David G. Binion. Impact of prior episodic dosing on performance of long-term infliximab maintenance therapy in Crohn’s disease. Inflamm Bowel Dis. 2010 Jul;16(7):1173-9.
    
2. Rafiee P, Stein DJ, Nelson VM, Otterson MF, Shaker R, Binion DG. Thalidomide Inhibits Inflammatory and Angiogenic Activation of Human Intestinal Microvascular Endothelial Cells (HIMEC).  Am J Physiol Gastrointest Liver Physiol. Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G167-76.
3. Nguyen DM, El-Serag HB, Henderson L, Stein DJ, Bhattacharyya A, Sampliner RE. Medication usage and the risk of neoplasia in patients with Barrett's esophagus. Clin Gastroenterol Hepatol. 2009 Dec;7(12):1299-304.
    
4. Stein DJ, Hashem B. El-Serag, M.D., M.P.H., John Kuczynski, M.D., Jennifer R. Kramer Ph.D., M.P.H., Richard E. Sampliner, M.D. The Association of Barrett’s Esophagus and Body Mass Index. Alimentary Pharmacology & Therapeutics. 2005 Nov 15;22(10):1005-10.

Abstracts

1. Daniel J. Stein, Benson T. Massey, Thangam Venkatesan, Richard Komorowski and Walter J. Hogan.  Chronic Idiopathic Enterocolitis (CIE): Maintaining a Corticosteroid Free Response with Immunosuppressive Therapy.  Digestive Disease Week, New Orleans, May 2010.
    
2. Kwiatt, James T., Stein, Daniel J., Naik, Amar S., Ananthakrishnan, Ashwin N., Perera, Lilani P. The 2009 Influenza Pandemic: Seasonal and H1N1 Influenza Vaccination Rates are Increasing in an IBD Population in 2009. Digestive Disease Week, New Orleans, May 2010.
    
3. Zadvornova Y, Ashwin N Ananthakrishnan, Stein DJ, Skaros S, Johnson K, Naik AS, Perera LP, Issa M. Infliximab monotherapy vs. combined infliximab-immunomodulator therapy in ulcerative colitis. Digestive Disease Week, New Orleans, May 2010.
    
4. Naik AS, Zadvornova Y, Issa M, Skaros S, Ward S, Ward A, Johnson K, Tyler K, Stein DJ, Perera LP, Ashwin N Ananthakrishnan. Tubular adenoma and low grade dysplasia in inflammatory bowel disease: Who is at risk? Digestive Disease Week, New Orleans, May 2010.
    
5. Daniel J. Stein, Ashwin Ananthakrishnan, Alex Ulitsky, Amar Naik, Charles Marn, Gary Sudakoff,  Mary F Otterson, Lilani Perera, David G Binion, Mazen Issa, Pre-operative small bowel follow through detects more strictures on a per stricture analysis than CT enterography when compared to intra-operative findings in patients with Crohn’s disease. American College of Gastroenterology annual meeting, San Diego, October 2009.
    
6. Dawn B. Beaulieu, Ashwin N. Ananthakrishnan,Yelena Zadvornova, Daniel J. Stein, Rachel Mepani, Stephen J. Antonik, Susan Skaros, Kathryn Johnson, Amar S. Naik, Lilani P. Perera, David G. Binion Seasonal Variation in HRQoL and Disease Activity in Patients with Inflammatory Bowel Disease: A Tertiary Care Center Experience,. Digestive Disease Week, Chicago, June 2009
    
7. Dawn B. Beaulieu, Ashwin N. Ananthakrishnan, Yelena Zadvornova, Daniel J. Stein, Rachel Mepani, Stephen J. Antonik, Susan Skaros, Kathryn Johnson, Amar S. Naik1, Lilani P. Perera1, David G. Binion. Does Duration of Disease Impact Health Related Quality of Life (HRQoL) in Inflammatory Bowel Disease? Digestive Disease Week, Chicago, June 2009
    
8. Daniel J. Stein, Mazen Issa, Sue Skaros, Josh F Knox, Kathryn Lemke, Jeanne Emmons, Mary F Otterson, Ashwin N Ananthakrishnan, David G Binion. “History of interrupted infliximab dosing significantly diminishes efficacy during long-term maintenance therapy in Crohn’s Disease.”  Gastroenterology. 134(4), Suppl 1: A-666, 2008.
    
9. Daniel J. Stein, HB El-Serag, J Kuczynski, JR Kramer, and RE Sampliner. “The Association of Barrett’s Esophagus and Body Mass Index.” American College of Gastroenterology 70th Annual Scientific Meeting. October 30 – November 2, 2005. Honolulu, Hawaii. A587
    
10. Daniel J. Stein, W Diaz-Calderon, and GL Woods. “Fibrosing Cholestatic Hepatitis: A Rare Complication After Renal Transplant.” American College of Physicians – Arizona Chapter Annual Meeting. Tucson, AZ. October 1-2, 2005.
     
11. Daniel J. Stein, R Chiou, B Houghton, G Ochuba. “An Unusual Case of Abdominal Pain and Urethritis.”  2003 American College of Physicians Annual Session. San Diego, CA. April 3-5.
     
12. Daniel J. Stein, P Rafiee, A Taras, TH Lamirand, PJ Fisher, H Ogawa, GL Telford, MF Otterson, CP Johnson, Binion DG,: Thalidomide inhibits inflammatory and angiogenic activation of human intestinal microvascular endothelial cells (HIMEC). Gastroenterology, 120: A278, 2001.
     
13. S Kugathasan, A Taras, Daniel J. Stein, PJ Fisher, TH Lamirand, RL Truitt, DG Binion,: Infliximab binds human monocytes, but not mucosal T cells in vitro: no direct anti-T cell mechanism of action. Gastroenterology, 118: A110, 2000.
     
14. S Kugathasan, Daniel J. Stein, RL Truitt, DG Binion,: Distinct mucosal T cell phenotypes in early and late pediatric Crohn's disease (CD): Increased naïve T cells are found in late, but not early CD. Gastroenterology, 118: A347, 2000.
     
15. DG Binion, KS Ramanujam, PJ Fisher, S Fu, MT Rivera, Daniel J. Stein, KT Wilson,: Loss of inducible nitric oxide synthase (iNOS) expression in inflammatory bowel disease (IBD) human intestinal microvascular endothelial cells (HIMEC) underlies leukocyte hyper adhesion. Gastroenterology, 116: A668, 1999.
     
16. S Kugathasan, Daniel J. Stein, MT Rivera, B Seetharam, DG Binion,: Plasma Transcobalamin II (TC II) is elevated in children with established, but not newly diagnosed Crohn's disease (CD): Acquired alteration in microvascular expression. Gastroenterology, 116: A755, 1999.
     
17. P Rafiee, PJ Fisher, Daniel J. Stein, CP Johnson, DG Binion,: ICAM-1, but not VCAM-1 expression is blocked with tyrosine phosphorylation inhibitors in activated human intestinal microvascular endothelial cells (HIMEC): Potential role of ERK and p38 MAPK. Gastroenterology, 116: A920, 1999.
     
18. MT Rivera, PJ Fisher, Daniel J. Stein, T Condon, J Tami, WE Shanahan, CF Bennett, DG Binion,: Antisense oligonucleotides, but not steroids, inhibit human intestinal microvascular endothelial cell (HIMEC) adhesion molecule expression and leukocyte binding: A novel therapeutic strategy in intestinal inflammation. Gastroenterology, 116: A669, 1999.