Gastroenterology & Hepatology

Gastroenterology & Hepatology

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Ivan M. Lang, PhD, DVM
Professor
Doctor of Philosophy (PhD)
Temple University, Philadelphia, Pennsylvania, 1980
Doctor of Veterinary Medicine (DVM)
University of Wisconsin School of Veterinary Medicine, 1996
Research Fellowship
Texas Tech University School of Medicine, Lubbock, Texas, 1979-1982

 

 

 

PUBLICATIONS
 

  1. Innes, DL, JS  Martin, IM  Lang, and  MF  Tansy. Evidence for the nonsymmetrical orientation of vagal efferent fibers. Iranian J. Med. Sci. 10: 1-17, 1979.

  2. Lang, IM,  DL Innes, and  MF Tansy. Areas in the amygdala necessary to the operation of the vagosympathetic pressor reflex. Experentia 35: 57-59, 1979.

  3. Lang, IM, JC Strahlendorf, HK Strahlendorf, and CD  Barnes. The effects of chronic  administration of naltrexone on appetite and water exchange in rats. Pharmacol. Biochem. Behav. 16: 909-913, 1982.

  4. Lang, IM, and MF Tansy. Minireview:  Neural and hormonal control of Brunner's gland secretion. Life Sciences 30: 409-417, 1982.

  5. Lang, IM, JD Strahlendorf, HK Strahlendorf, and CD  Barnes. Investigations of the preferential reduction in drinking behavior by opiate antagonists. Proc. West Pharmacol. Soc. 25: 293-297, 1982.

  6. Lang, IM, and CD  Barnes. The effects of cyclobenzaprine on locus coeruleus cells in vitro. Proc. West Pharmacol. Soc. 25: 361 - 363, 1982.

  7. Lang, IM, and CD  Barnes. Cyclobenzaprine effects on locus coeruleus cells in tissue slice. Neuropharmacology 22: 249 - 252, 1983.

  8. Lang, IM, and MF  Tansy. Mechanisms of the secretory and motor responses of the Brunner's gland region of the intestine to duodenal acidification. Pflugers Arch. 396: 115-120, 1983.

  9. Strahlendorf JC, HK Strahlendorf, R  McKowan-Pullian, M  Hughes, and IM  Lang. Chronic administration of naltrexone alters central catecholamine levels but not the development of hypertension in spontaneously hypertensive rats. Neuropharmacology 21: 1195-1998, 1983.

  10. Sarna, SK, and IM  Lang. The dose-and-time dependent biphasic response of morphine on  migrating myoelectric complex cycling. J. Pharmacol. &  Exp. Ther. 234: 814-820, 1985.

  11. Lang IM, SK  Sarna, and RE  Condon. Gastrointestinal motor correlates of vomiting in the dog:Quantification and identification as an independent phenomenon. Gastroenterology 90: 40-47, 1986.

  12. Lang, IM, SK  Sarna, and RE  Condon. The  myoelectric and contractile effects of motilin on the dog small intestine in vivo. Dig. Dis. Sci. 31: 1062-1072, 1986.

  13. Lang ,  IM, SK  Sarna, and RE  Condon. The generation of phases I and II of the migrating  myoelectric complex in the dog. Am. J. Physiol. 251: G201-G207, 1986.

  14. Lang,  IM, SK  Sarna, and RE  Condon. The gastrointestinal myoelectrical correlates of vomiting in the dog. Am. J. Physiol.  251: G630 - G838, 1986.

  15. Frantzides CT, SK  Sarna, T  Matsumoto, IM  Lang, and RE  Condon. An intrinsic neural pathway for long intestino-intestinal inhibitory reflexes. Gastroenterology 92: 594-603, 1987.

  16. Lang,  IM, J  Marvig, and SK  Sarna. Comparison of the gastrointestinal responses to CCK-8 and associated  with vomiting. Am. J. Physiol. 254: G254-G263, 1988.

  17. Karaus  M, KR  Prasad, SK  Sarna, and IM  Lang. Differential effect of GLN4-neurotensin on circular and longitudinal  muscle of dog ileum in vitro. Am. J. Physiol.  253: G566-G572,1987.

  18. Sarna SK, KR  Prasad, and IM  Lang. Giant migrating contractions of the canine cecum. Am. J. Physiol. 254: G595-G601, 1988.    

  19. Groner JI, R  Schumann, IM  Lang, and GL  Telford. Fentanyl and alfentanyl initiate the migrating myoelectric complex but not the vomiting response in canine small intestine. Current Surgery 45: 209-212, 1988.

  20. Lang,  IM, and J  Marvig. Functional localization of specific receptors  mediating the GI motor correlates of vomiting. Am . J. Physiol. 256: G92-G99, 1989.

  21. Sarna SK, and IM  Lang. Colonic  motor response to a  meal in the dog. Am. J. Physiol. 20: G830- G835, 1989.

  22. Cook IJ, WJ  Dodds, B  Massey, IM  Lang, M  Kern, and J Brasseur. Opening  mechanisms of the human upper esophageal sphincter. Am. J. Physiol. 20: G748-G759, 1989.

  23. Lang,  IM.  Digestive tract motor correlates of vomiting and  nausea. Can. J. Physiol. Pharmacol.  68: 242-253, 1990.

  24. Dantas RO, IJ  Cook, WJ  Dodds, MK  Kern, IM  Lang, and JG  Brasseur. Biomechanics of cricopharyngeal bars. Gastroenterology 99: !269 - 1274, 1990.

  25. Dantas RD, Kern  MR, Massey BT, Dodds  WJ, Kahrilas PJ, Brasseur JG, Cook IJ and Lang  I M. Effect of swallowed bolus variables on oral and pharyngeal phases of swallowing. Am. J. Physiol. 258: G675-G681, 1990.

  26. Lang,  IM, and SK Sarna. The role of adrenergic receptors in the initiation of vomiting and its gastrointestinal motor correlates. J. Pharmacol. Exp. Ther. 263: 395-403, 1992.

  27. Lang,  IM,  RO Dantas, IJ Cook, and WJ Dodds. Videoradiographic, manometric and electromyographic assessment of upper esophageal sphincter function in the dog. Am. J. Physiol. 260: G911-G919, 1991.

  28. Lang,  IM,  WJ Dodds, SK Sarna.  The pharyngeal, esophageal, and gastric responses associated with vomiting. Am. J. Physiol. 265: G963-G972, 1993.

  29. Shaker, J Ren, B  Medda, IM  Lang, V  Cowles, S Jaradeh. Identification and characterization of the esophagoglottal closure reflex in cat. Am. J. Physiol. 266: G147-G153, 1993.

  30. Lang, IM  and R  Shaker. An update on the physiology of the components of the upper esophageal sphincter.  Dysphagia 9:229-232, 1994.

  31. Shaker, R and IM  Lang. The effect of aging on pharyngeal  motor function. Dysphagia 9:233-240, 1994.

  32. Medda B, IM  Lang,  R  Layman, WJ  Dodds, WJ  Hogan, and R  Shaker. Characterization and quantification of a pharyngo-UES contractile reflex in the cat. Am. J. Physiol. 267: G972-G983, 1994.

  33. Kusano, M., WJ  Hogan, IM  Lang, J.L. Bonnevier, B.T. Massey, and R  Shaker.  Initiation of esophageal secondary peristalsis by slow fluid infusion in the opossum: effect of hydrochloric acid. Am. J. Physiol.  270:G927-G931, 1996.

  34. Daisaku, O., S.K. Sarna, R.E. Condon, and IM  Lang.  Inhibition of nitric oxide synthase in the brain suppresses colonic motor activity.  Am. J. Physiol. 270: G717- G724, 1996.

  35. Ohta, D., C. Lee, S.K. Sarna, R.E. Condon, and I.M. Lang.  Central inhibition of nitric oxide synthase modulates upper gastrointestinal motor activity. Am. J Physiol. . 272:G417-G424, 1997.

  36. Shaker, R., J. Ren, P. Xie, I.M. Lang, E. Bardan, Z. Sui.  Characterization of the pharyngo-UES contractile reflex in humans. Am. J. Physiol. 273: G854-G858, 1997.

  37. Lang, I.M. and R. Shaker.  Anatomy and physiology of the upper esophageal sphincter. Am. J. Med Suppl. 24: 50S-55S, 1997.

  38. Shaker, R. and I.M. Lang. Reflex mediated airway protective mechanisms against retrograde aspiration. Am. J. Med Suppl. 24: 64S- 73S, 1997.

  39. Medda, B., IM Lang,  M. Kusano, WJ  Hogan, R  Shaker. Correlation of the electrical and  mechanical activities of the cricopharyngeus  muscle. Am. J. Physiol. 273:G470-G479, 1997.

  40. Lang, I.M., B.K. Medda, P. Xie, and R. Shaker. Characterization and mechanisms of the pharyngoesophageal inhibitory reflex. Am J. Physiol. 275: G1127-G1136, 1998.

  41. Shaker, R., B.K. Medda, J. Ren, S. Jaradeh, P. Xie and I.M. Lang. Pharyngoglottal closure reflex: identification and characterization in a feline model. Am. J. Physiol. 275: G521-G525, 1998.

  42. Medda, B.K., R. Shaker, I.M. Lang, M. Kern. Role of pharyngeal and laryngeal muscles  in the airway protective of the cat. Am. J. Physiol. (In preparation).

  43. Lang, I.M. , S.K. Sarna, and R. Shaker. Gastrointestinal motor and myoelectrical correlates of motion sickness. Am. J. Physiol. 277: G642-G652, 1999.

  44. Lang, I.M.  Noxious stimulation of emesis. Dig Dis Sci 44: 58S-63S, 1999.

  45. Easterling, C., M. Bousarma, I.M. Lang, M. Kern, T. Nitschke, E Bardan, and R. Shaker. Pharyngeal dysphagia in posttranshiatal esophagectomy patients: correlation with deglutitive biomechanics. Ann Thoracic Surg. 69:989-992, 2000

  46. Lang, IM and R. Shaker. An overview of the upper esophageal sphincter. Current Gastroenterol 2:2000.

  47. Ren, J , P. Xie, I.M. Lang, E Bardan, Z. Sui, and R Shaker. Deterioration of the pharyngo-UES contractile reflex in the elderly. The Laryngoscope 110: 1563-1566, 2000.

  48. Dua, K.S., R. Kozarek, J. Kim, J. Evans, B.K. Medda, I. M. Lang, W.J. Hogan, and R. Shaker. Self-expanding metal esophageal stent with anti-reflux mechanism. Gastrointestinal Endoscopy 53: 603-613, 2001.

  49. I.M. Lang, B.K. Medda, and R. Shaker. Mechanisms of reflexes induced by esophageal distension. Am J. Physiol. (in press).

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