Basic and Translational Science
Doctor of Philosophy
Direct entrance into Basic and Translational Science Program not available. Enrolled Basic Science PhD seekers may apply to this program in their third year of study.
The program builds on a strong foundation of core basic science knowledge and develops competencies associated with successful scientific innovation and research in a multidisciplinary collaborative learning environment. In this program, students are trained to think broadly about the clinical applications of the basic sciences and to carry out research bridging the gap between basic science and clinical practice. Students will come into graduate school through the Interdisciplinary Program in Biomedical Sciences, Interdisciplinary Program in Neuroscience, Physiology Graduate Program or Biophysics Graduate Program in Imaging.
Program Admissions Requirements
In addition to the general Graduate School admission requirements, this program has additional specific requirements.
Basic Science PhD seekers who are in good academic standing may express interest in the program near the end of the first year when a basic science advisor is chosen. If the advisor chosen is willing to help you pursue the translation component you will later apply to the BTS Program.
Program Degree Requirements
Students will satisfy the PhD requirements of their Basic Science Department and those of the Translational Science portion of the program.
Six credits of advance coursework to be determined by the basic science department, counted toward both the departmental requirements and the BTS requirements.
Six credits of coursework selected from a menu of Clinical Translational Courses. “Boundaries of Science and Medical Practice” is required, as is a Biostatistics course.
Within the 12-credit requirement, a pathophysiological component must be present.
21150 Boundaries of Science and Medical Practice. 1 credit.
Translational Science will be explored through term-based learning with class discussion of assigned cases. At the end of the course, the students will describe and analyze the use of appropriate clinical and translational research techniques, evidence-based medicine and outcomes research methods; identify gaps between basic science knowledge and clinical practice for specific clinical questions pertinent to their area of research; propose the steps needed to apply basic science knowledge to outline possible experiments that are feasible and compliant with regulatory and ethical issues; and identify significant clinical questions/hypotheses that would benefit from translational research programs.
Biostatistics Course Requirement
(at least 1 credit) See course description within specific program.
04200 Biostatistics I. 3 credits. (see Biostatistics program listing)
04202 Principles of Biostatistics. 1 credit. (see Biostatistics program listing)
18204 Introduction to Biostatistics. 3 credits. (see Public Health program listing)
Pathophysiology Component Requirement
(at least 1 credit)
12206 Integrated Graduate Neuroscience—4 Credits
03251 Free Radicals in Biology—3 Credits
01152 Human Development—1 Credit
01153 Cell and Tissue Biology—4 Credits
01205 Integrated Neuroscience—6 Credits
01207 Introduction to Neuroscience—2 Credits
01210 Advanced Clinical Human Anatomy—1-3 Credits
01212 Developmental and Stem Cell Biology—3 Credits
01257 Biology of Vision—3 Credits
05259 Mucosal Immunity—1 Credit
05260 Mucosal Pathogenesis—1 Credit
05261 Bacterial Toxin-Mucosal Cell Interactions—1 Credit
05262 Tumor Immunology—1 Credit
05263 Signaling in the Immune System—1 Credit
05264 Developmental Immunology—1 Credit
05265 Immunological Tolerance—1 Credit
05266 Clinical Immunology—1 Credit
07202 Survey of Pharmacology—3 Credits
08210 Endocrine Regulation and Common Disease—1 Credit
08212 Critical Reading in Respiratory Physiology—1 Credit
08253 Advanced Renal Physiology—1 Credit
08273 Special Topics in Neuroscience—1 Credit
All elective courses for the Clinical and Translational Science MS
will be available to students in the Basic and Translational Science PhD Program.
Six credits of coursework to be selected.