Medical Scientist Training Program

Max Cayo

3rd Year Graduate Student
5th Year MSTP Student

mcayo@mcw.edu

Research Interests

• Functional Genomics, Biostatistics, Regenerative Medicine.

Education

• B.S. 2007, University of Wisconsin – Madison
  • Major: Molecular Biology

Research Experience

• University of Wisconsin - Madison, 2006-2008
  • Advisor: Dr. Herbert Chen
  • Trewartha Undergraduate Honors Research Grant. Thesis title: Valproic Acid: A Novel Therapy for Medullary Thyroid Cancer.
  • Hilldale Undergraduate/Faculty Research Fellowship, University of Wisconsin – Madison
  • NIH T35 National Research Service Award Short-Term Training Grant, University of Wisconsin – Madison
• Northwestern University, Feinberg School of Medicine, 2008-2009
  • Advisor: Dr. S. David Stulberg, Dr. Ronak Patel
  • Topic: Long-term clinical study of hip implants of varying femoral component lengths.

Publications

Journal Articles/Book Chapters

• Haymart MR, Cayo M, Chen H. Thyroid Hormone Replacement in Women of Reproductive Age: Is Surgeon Knowledge Related to Operative Volume? Thyroid. 2010 Jun; 20(6):627-31
• Greenblatt DY, Cayo MA, Jaskula-Sztul R, Haymart M, Kunnimalaiyaan M, Chen H. Suberoyl Bishydroxamic Acid Inhibits Cellular Proliferation by Inducing Cell Cycle Arrest in Carcinoid Cancer Cells. Journal of Gastrointestinal Surgery. 2007 Nov. 11. (11):1515-20; discussion 1520.
• Cayo M, Greentblatt DY, Kunnimalaiyaan M, Chen H. RAF1 (v-raf-1 murine leukemia viral oncogene homolog 1). Atlas of Genetics and Cytogenetics in Oncology and Haematology. March 2007. URL: http://AtlasGeneticsOncology.org/Genes/RAF1ID42032ch3p25.html
• Cayo M, Greenblatt DY, Kunnimalaiyaan M, Chen H . NOTCH1 (Notch homolog 1, translocation-associated (Drosophila)). Atlas of Genetics and Cytogenetics in Oncology and Haematology. August 2007. URL: http://AtlasGeneticsOncology.org/Genes/NOTCH1ID30ch9q34.html
• David Yu Greenblatt, MD, Max A. Cayo, BS, Li Ning, MD, Muthusamy Kunnimalaiyaan, PhD, and Herbert Chen, MD, FACS. Valproic Acid Activates Notch1 Signaling and Induces Apoptosis in Medullary Thyroid Cancer Cells. Annals of Surgery. 2008 Jun; 247(6):1036-40.
• Max A. Cayo, Ashley K. Cayo, Sarah M. Jarjour, Herbert Chen. Sodium Butyrate Activates Notch1 Signaling, Reduces Tumor Markers, and Induces Cell Cycle Arrest and Apoptosis in Pheochromocytoma. American Journal of Translational Research. 1(2): 178-183; 2009.
• Haymart MR, Cayo M, Chen H. Papillary Thyroid Microcarcinomas: Big Decisions for a Small Tumor. Annals of Surgical Oncology. 2009 Nov; 16(11):3132-9.

Abstracts and Meetings

• Max A. Cayo, BS, Ronak M. Patel, MD, S. David Stulberg, MD. Metaphyseal Engaging Short-Stem Femoral Implants. Poster: 123rd Annual Meeting of The American Orthopaedic Association, San Diego, California, June 2010.
• Michelle Boockmeier B.S., Max Cayo, Joel Adler B.A., Sarah Jarjour, Muthusamy Kunnimalaiyaan Ph.D., Herbert Chen M.D. Raf-1 Mediated Skp2 Oncogene Suppression in Medullary Thyroid Cancer. 2006 Wisconsin Surgical Society Meeting.
• David Yu Greenblatt, Abram Vaccaro, Mary Ndiaye, Renata Jaskula-Sztul, Christopher Platta, Michelle Boockmeier, Joel Adler, Max Cayo, Yi Wei Zhang, Catherine McManus, Sarah Jarjour, Muthusamy Kunnimalaiyaan, and Herbert Chen. Identification of a Compound that Activates Notch1 Signaling and Inhibits the Neuroendocrine Phenotype in Carcinoid Cells. 1st Annual Meeting of the North American Neuroendocrine Tumor Society, Portland, Oregon, September 2006.
• Muthusamy Kunnimalaiyaan, Abram Vaccaro, Mary Ndiaye, David Greenblatt, Renata Jaskula-Sztul, Yi Wei Zhang, Catherine McManus, Molly Kloosterboer, Max Anthony Cayo, Michelle Boockmeier, Joel T. Adler, Chris Platta, Sarah Jarjour and Herbert Chen. Targeting Notch1 Signaling as a Therapy for Neuroendocrine Tumors. 1st Annual Meeting of the North American Neuroendocrine Tumor Society, Portland, Oregon, September 2006. Award for best poster.
• David Yu Greenblatt, MD, Max A. Cayo, BS, Li Ning, MD, Muthusamy Kunnimalaiyaan, PhD, and Herbert Chen, MD, FACS. Valproic Acid Activates Notch1 Signaling and Inhibits Growth in Medullary Thyroid Cancer Cells. 2007 Meeting of the American Association for Endocrine Surgeons, Tucson, Arizona, April 2007. Award for best poster.
• Max Cayo and Herbert Chen. Valproic Acid: A Novel Therapy for Medullary Thyroid Cancer Poster presentation at 2007 UW-Madison Undergraduate Research Symposium.
• Greenblatt DY, Cayo MA, Jaskula-Sztul R, Haymart M, Kunnimalaiyaan M, Chen H. Suberoyl Bishydroxamic Acid Activates Notch1 Signaling and Inhibits Proliferation by Inducing Cell Cycle Arrest in Carcinoid Tumor Cells. 48th Annual Meeting of the Society for Surgery of the Alimentary Tract, Washington, DC, May 2007. Presented at the SSAT Residents & Fellows Conference and the SSAT Meeting Plenary Session.
• Greenblatt DY, Cayo MA, Vaccaro A, Jaskula-Sztul R, Ning L, Haymart M,Kunnimalaiyaan M, Chen H. Valproic Acid Activates Notch1 Signaling and Suppresses Growth in Carcinoid Tumor Cells. 2007 Meeting of the Wisconsin Surgical Society, Kohler, Wisconsin, October 2007. Winner of award for best basic science resident research presentation.
• Greenblatt DY, Cayo MA, Jaskula-Sztul R, Ning L, Haymart M, Kunnimalaiyaan M, Chen H. Anti-Proliferative Effects of Histone Deacetylase Inhibitors in Carcinoid Cancer Cells. 1st Annual Symposium of the North American Neuroendocrine Tumor Society, Bermuda, February 2008.
• Max Cayo, BS, Ashley Cayo, MD, Sarah Jarjour, Herbert Chen, MD, FACS. Sodium Butyrate Inhibits Cellular Proliferation and Reduces Aberrant Hormone Secretion in Pheochromocytoma. Poster session: Annual Meeting of the Wisconsin Surgical Society, Kohler, Wisconsin, November 2008.
• Max Cayo, BS, Sarah Jarjour, Ashley Cayo, MD, Herbert Chen, MD, FACS. Sodium Butyrate Inhibits Cellular Proliferation and Reduces Aberrant Hormone Secretion in Pheochromocytoma. Oral presentation: Academic Surgical Congress, Fort Meyers, Florida, February 2009.
• Max Cayo, BS, Ashley Cayo, MD, Sarah Jarjour, Herbert Chen, MD, FACS. Resveratrol Activates Notch1 Signaling, Inhibits Cellular Proliferation, and Diminishes Neuroendocrine Markers in Pheochromocytoma. Oral presentation: Society for Surgical Oncology Cancer Symposium, Phoenix, Arizona, March 2009.
• MA Cayo, H Chen, MR Haymart. Papillary Thyroid Microcarcinomas: Big Decisions for a Small Tumor. Poster session: ENDO 09, 91^st annual meeting of The Endocrine Society, Washington, DC, June 2009.

Interests

• Spending time with my wife Ashley and our dog. Road bike racing with the Brazen Dropouts cycling team. Snowboarding. Triathlon. Economics and politics.