Neurology

Paul E. Barkhaus, MD

Professor of Neurology
Director, Neuromuscular Diseases, Milwaukee Veterans Administration Medical Center
Director, Amyotrophic Lateral Sclerosis Program (ALS Association Certified Center 2006- )
Director, Clinical Neurophysiology Residency

Specialty: Adult Neurology

Sub-Specialty:

• Amyotrophic Lateral Sclerosis
• Electromyography
• Neuromuscular Disease

Education:

• Doctor of Medicine, Wayne State University School of Medicine, Detroit, MI, 1975

Training:

• Resident, Department of Neurology, Wayne State University, Detroit, Michigan, 1975-1978
• Electromyography Fellowship, Department of Neurology, University of Minnesota, Minneapolis, Minnesota, 1978-1979
• Clinical Neuromuscular Diseases Fellowship, Department of Neurology, University of Arizona, Tucson, Arizona, 1979-1980
• Single Fiber Electromyography, Uppsala University, Uppsala, Sweden, 1980
• Visiting Scientist, November, Department of Clinical Neurophysiology Uppsala University, Uppsala, Sweden, 1985-1986
• Senior Research Fellowship in Electromyography, Duke University Medical Center, Durham, North Carolina, 1986-1987

Societies:

• American Academy of Neurology (Fellow)
• American Neurological Association
• American Association of Electromyography and Electrodiagnosis (Active Member by Examination)
• Wisconsin Neurological Society (President, 2000-2001)

Awards/Honors:

• Distinguished Service Award, Wayne State University School of Medicine, 1975
• Trainee Award, Federation of Western Societies of Neurological Sciences, 1980
• Special Commendation, Minnesota Chapter, Myasthenia Gravis Foundation, 1983
• Special Commendation, Cincinnati Chapter, Muscular Dystrophy Association, 1983
• Alumnus Hall of Fame, Allen Park High School, Allen Park, Michigan, 1987
• Distinguished Visitor to USS Theodore Roosevelt, by invitation of Commander, U.S. 2nd Fleet, 2000
• Clinical Neurophysiology Teacher of The Year, Department of Neurology, Medical College of Wisconsin, 2001
• Selected for inclusion to "America's Top Physicians", Consumers' Research Council of America, 2006
• Elected to Active Membership, American Neurological Association
• Selected for inclusion in "Best Doctors^®" (2005- )

Brief Clinical/Research Interest Statement:

Clinical Interests:

• Amyotrophic Lateral Sclerosis
• Quantitative Electromyography

Research Interests:

• Phase III Clinical Trial of IGF - 1 in Patients with ALS
• Serial quantitative EMG studies in inclusion body myositis
• Analysis of F waves

Publications:

Original Publications

1. Barkhaus PE, Periquet MI, Nandedkar SD: Quantitative electromyography studies in sporadic inclusion body myositis.  Muscle Nerve 22:480-87,1999.
2. Nandedkar SD, Barkhaus PE, Sanders DB, Stalberg EV: Some observations on fibrillations and positive sharp waves. Muscle Nerve 23:888-894, 2000.
3. Zucca C, Binda S, Borgatti R, Triulzi F, Radice L, Botte C, Barkhaus PE, Barbi M: Congenital Cytomegalovirus Infection and Cortical Maldevelopment: A Retrospective Diagnosis. Neurology 61(11):710-712, 2003.
4. Nandedkar SD, Nandedkar, D, Stalberg EV, Barkhaus PE: Motor Unit Indexing (MUI): A new method to study the number of MUs. IEEE Transactions in Biomedical Engineering, 2004; 51(12):2209-2211.
5. Barkhaus PE, Collins MI, Nandedkar SD: Influence of the surface EMG electrode on the compound muscle action potential. Electromyography & Clinical Neurophysiology, 2006; 46:235-239.
6. Barkhaus PE, Roberts, MM, Nandedkar SD: "Facial" and standard concentric needle electrodes are not interchangeable. Electromyography & Clinical Neurophysiology, 2006; 46:259-261.
7. Barkhaus PE, Nandedkar SD: Serial quantitative electrophysiologic studies in sporadic inclusion body myositis. Electromyography & Clinical Neurophysiology, 2006; 47: 97-104.
8. Barkhaus PE, Nandedkar SD: Slow myotonia. Muscle Nerve, 2006; 34: 532-533.
9. Nandedkar SD, Barkhaus PE: Contribution of reference electrode to the compound muscle action potential. Muscle Nerve, 2007; 36:87-92.

Books, Chapters and Reviews:

1. Nandedkar SD, Barkhaus PE: Quantitative EMG Analysis, in Katirji B, Kaminski HJ, Preston DC, Ruff RL, Shapiro BE: Neuromuscular Disorders in Clinical Practice. Boston, Butterworth-Heinnemann, 2000.
2. Barkhaus PE: Kennedy's Disease. .  In Lorenzo NY, Lutsep  HL (senior eds): eMedicine: Neurology. St. Petersberg, eMedicine Corp, 2001.
3. Barkhaus PE: Motor Unit Action Potential Quantitation. Workshop Handout. Rocester, MN, American Association of Electrodiagnostic Medicine, 2001, 2nd Edition.
4. Barkhaus PE, Nandedkar SD: EMG Evaluation of the Motor Unit: "The Electrophysiologic biopsy": Remodeling of the motor unit in neuromuscular  disorders.  In Lorenzo NY, Lutsep HL (senior eds): eMedicine: Neurology. St. Petersberg, eMedicine Corp, 2001.
5. Barkhaus PE: Motor unit action potential quantitation. Workshop Handout: & REVIEWS: American Association of Electrodiagnostic Medicine, Rochester, MN, 2001, 2nd Edition.
6. Nandedkar SD, Barkhaus PE: Quantitative Analysis: Objective & Interactive Assessment in EMG, in Bertorini (ed) Evaluation and Diagnostic Tests in Neuromuscular Disorders. Boston, Butterworth-Heinneman, 2002.
7. Barkhaus PE: The Electronic Myoanatomic Atlas for Clinical Electromyography. Hopewell Junction, NY, CASA Engineering, 2005, 2nd ed. (Book on multi-media DVD).
8. Collins MI, Collins MP, Barkhaus PE: Inclusion Body Myositis. In Quan D, Lorenzo NY, Lutsep HL (senior eds): eMedicine Journal (Neurology) [serial online]. 2005. Available at http://www.emedicine.com/neuro/topic422.htm.
9. Nandedkar SD, Barkhaus PE: Quantitative Analysis: Objective and Interactive Assessment in EMG, in Bertorini T (ed): Evaluation and Tests in Neuromuscular Disorders. Boston, Butterworth Heinnemann, 2002.
10. Nandedkar SD, Nandedkar, D, Stalberg EV, Barkhaus PE: Motor Unit Number Indexing (MUNIX): A pilot study. In Bromberg M: Motor Unit Number Estimation (MUNE): Supplements to Clinical Neurophysiology, Volume 55. New York, Elsevier, 2003, p 133-140.
11. Barkhaus PE: Motor Nerve Conductions, Late Responses, and Reflexes. Hopewell Junction, NY, CASA Engineering, 2007, (Book on multi-media DVD).