Orthopaedic Surgery Cell Biology Laboratory
The cell biology laboratory investigates the interactions between bone cells and orthopaedic implants. Research activities include studies into the role of orthopaedic wear debris in the generation of cytokines by cultured osteoblasts, as well as alterations in bone associated proteins in response to orthopaedic implant materials.
Facilities include equipment for the tissue culture of human and other cells, as well as incubators and hoods. Cytokine and protein assay methods include bioassay and ELISA techniques, and analysis of m-RNA synthesis which is carried out through the use of the polymerase chain reaction after reverse transcription.
Access to spectroscopy, ultracentrifugation, and other techniques is available through the Department of Biochemistry at the Medical College.
The cell biology laboratory in the Department of Orthopaedic Surgery provides a unique environment for collaboration between basic scientists and orthopaedic surgeons.