Medical trainees need professional development training as they care for patients and their families during serious illness and end of life. Supervision is a professional activity in which trainees develop understanding and awareness of influences such as beliefs and culturally embedded values that contribute to clinical practice. It involves observation, evaluation, feedback and facilitation of self-assessment. It provides opportunities to discuss difficult or emotionally charged encounters with patient and families, which promotes the development of a self-reflective and self-respectful approach to clinical practice. This study examines the effects of bi-weekly supervision with a licensed psychologist, Jo Weiss, PhD, on the professional development of medical doctors working with the seriously ill through quantitative and qualitative methods.