Research Interests
Medicinal Chemistry
Natural Products Isolation and Identification
Organometalics
Synthetic Methodology
Total Synthesis
Selected Publications
Tunctan, B., Korkmaz, B., Butaralioglu, C.K., Firat, S.S., Anjaiah, S., Falck, J.R., Roman, R.J., and K.U. Malik: A 20-Hydroxyeicosatetraenoic Acid Agonist, N-[20-Hydroxyeicosa-5(Z),14-(Z)-Dienoyl]Glycine, Opposes the Fall in Blood Pressure and Vascular Reactivity in Endotoxin-Treated Rats. Shock 2008; (30):329-335
Li, D-R., Murugan, A., and J.R. Falck: Enantioselective, Organocatalytic Oxy-Michael Addition to γ/δ-Hydroxy-α,β-enones: Boronate-Amine Complexes as Chiral Hydroxide Synthons.
J. Am. Chem. Soc., 2008; (130):46-48
Illies, C., Gromada, J., Fiume, R., Leibiger, B., Yu, J., Juhl, K., Yang, S-N., Barma, D., Falck, J.R., Saiardi, A., Barker, C.J., and P-O Berggren: Requirement of Inositol Pyrophosphates for Full Exocytotic Capacity in Pancreatic β Cells.
Science 2007; (318):1299-1302
Falck, J.R., He, A., Fukui, H., Tsutsui, H., and A. Radha: Synthesis and Sterochemical Assignment of FR252921, a Promising Immunosuppressant
. Angew.
Chem. Int. Ed. 2007; (46):4527-4529
Baati, R., Mioskowski, C., Kashinath, D., Kodepelly, S., Lu, B., and J.R. Falck: Steroselective Synthesis of Methyl (Z)-α-Methoxyacrylates via Two-Carbon Homologation of Aldehydes. Tetrahedron Lett. 2009; (50):402-405
Rasko, D.A., Moriera, C.G., Li, D.R., Readings, N.C., Ritchie, J.M., Waldor, M.K., William, N., Taussig, R., Wei, S., Roth, M., Hughes, D.T., Huntley, J.F., Fina, M.W., Falck, J.R., and V. Sperandio:
Targeting QseC Signaling and Virulence for Antibiotic Development. Science 2008; (321):1078-1080