Pharmacology and Toxicology

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Johnathan Ebben

3rd Year MSTP Student
Graduate Student
Department of Pharmacology and Toxicology

B.S., Marquette University

Faculty Advisor:  Dr. Ming You
Email: jebben@mcw.edu
Phone: (414) 955-2803


Research Interest

I am interested in examining the role of key developmental genes and regulators of pluripotency in lung tumor development.  Mounting evidence suggests that many of these genes may have multifaceted roles in both the development and attenuation of tumorigenesis.  I am also interested in exploring the potential role of tumor vaccines in the context of lung cancer.


Publications

Liu P,Morrison C,Wang L,Xiong D,Vedell P,Cui P,Hua X,Ding F,Lu Y,James M,Ebben JD,Xu H,Adjei AA,Head K,Andrae JW,Tschannen MR,Jacob H,Pan J,Zhang Q,Van den Bergh F,Xiao H,Lo KC,Patel J,Richmond T,Watt MA,Albert T,Selzer R,Anderson M,Wang J,Wang Y,Starnes S,Yang P,You M Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis.2012 Jul;33(7):1270-6.

Ebben JD, Zorniak M, Clark PA, Kuo JS.  Introduction to induced pluripotent stem cells: advancing the potential for personalized medicine.  World Neurosurg. 2011 Sep-Oct;76(3-4):270-5.

Ebben JD, Treisman DM, Zorniak M, Kutty RG, Clark PA, Kuo JS. The Cancer Stem Cell Paradigm: A New Understanding of Tumor Development and Treatment. Expert Opin Biol Ther 14(6): 621-632 (2010).

Ebben JD, Rocque BG, Kuo JS.  Tumour vaccine approaches for CNS malignancies: progress to date. Drugs 69 (3):241-9 (2009).

Clark PA, Treisman DM, Ebben, JD, Kuo JS.  Developmental Signaling pathways in brain tumor-derived stem-like cells.  Developmental Dynamics 236 (12): 3297-308 (2007).

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