Study investigated whether arterial inflammation is a biomarker for cardiovascular disease in patients with HIV
July 25, 2012 College News - Sharath Subramanian, MD, cardiology fellow at the Medical College of Wisconsin, is first author on a paper published in the July 25 online issue of JAMA, the Journal of the American Medical Association. The paper, Arterial Inflammation in Patients with HIV, investigated the role of arterial inflammation leading to increased cardiovascular disease in patients with human immunodeficiency virus (HIV).
Coronary artery disease is increased in patients with HIV, but the specific reasons for that are unknown. Dr. Subramanian and his team tested whether arterial wall inflammation is increased in patients with HIV and could be used as a biomarker. His study showed that the participants infected with HIV had increased arterial inflammation, when compared to non-infected control participants with similar traditional cardiac risk factors using noninvasive Positron Emission Tomography (PET) imaging.
Dr. Subramanian, who started his MCW fellowship July 2011, was affiliated with Harvard Medical School and Massachusetts General Hospital when the study was conducted.
Online version of Arterial Inflammation in Patients with HIV